Results 101 to 110 of about 21,639 (283)

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Hydrological Simulation and Error Correction in Source Area of Yellow River Based on VIC-BJP Model

Renmin Zhujiang
The source area of the Yellow River is an important runoff-producing region throughout the Yellow River Basin. Accurate hydrological simulation results of the source area for evaluating regional water resources can provide valuable support to ensure ...
ZHU Changchang, HUANG Huaping
doaj   +2 more sources

Seasonal precipitation forecasts over China through calibration and combination of multiple CGCMs

Shui kexue jinzhan, 2014
To alleviate systematic deficiencies of two latest seasonal forecast systems in forecasting seasonal precipitation over China,a slightly modified Bayesian joint probability (BJP) modelling approach was employed to calibrate the ensemble means of the raw ...
PENG Zhaoliang, Q. J. WANG, WANG Ziru, WANG Guoli, XU Chao   +4 more
doaj   +1 more source

Emergence of BJP

Following the fall of the Janata Party administration in 1980, the Bharatiya Janata Party (BJP) became a significant political force in India. Its origins can be discovered in the Bharatiya Jana Sangh, an older political group that Shyama Prasad Mukherjee founded in 1951. The Rashtriya Swayamsevak Sangh (RSS) had an ideological effect on the Jana Sangh,
Uma Shankar, Dr. Rakesh Kumar Jaiswal
openaire   +2 more sources

Differential segment‐specific signalling pathways for guanylate cyclase C‐activated anion secretion in murine ileocolon

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Guanylate cyclase‐C (GC‐C) is the receptor for endogenous (uro)guanylin peptides, bacterial toxins and pharmacological analogues. Receptor activation leads to intestinal fluid loss, but also activates an antiproliferative pathway and is a promising target in colorectal cancer therapy.
Renjie Xiu, Johannes Reiner, Franz Hofmann, Azam Salari, Ursula Seidler   +4 more
wiley   +1 more source

PERANAN SEKTOR PERTANIAN DALAM PEMBANGUNAN WILAYAH DI ERA OTONOMI DAERAH KABUPATEN KARANGANYAR

Caraka Tani: Journal of Sustainable Agriculture, 2009
In era regional autonomy which the regional economic development not follow the central development paradigm, but the development base on the initiative and the carrying capacity of region.
Agustono Agustono, Ropingi Ropingi, Catur Tunggal BJP   +2 more
doaj   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source

The Political Economy of Religion and Politics in India [PDF]

, 2016
The paper will examine the dramatic rise of the right-wing Hindu organisations in India, especially since the 1990s. Most prominent among these organisations are RSS, BJP, VHP, Bajang Dal and Shiv Sena.
Siddiqui, Kalim, SIDDIQUI, Kalim; Business School University of Huddersfield UK   +1 more
core   +1 more source

Targeting hexokinase 2 to induce breast cancer cell senescence

British Journal of Pharmacology, EarlyView.
Background and Purpose Hexokinase 2 (HK2) is a key enzyme linked to high tumour cell proliferation. Its inhibitors such as 3‐bromopyruvic acid (3‐BP) induce cancer cell death, highlighting HK2 modulation as potential anti‐cancer treatment. However, standard chemotherapies often cause the emergence of senescent cancer cells, which goes along with cell ...
Helmut Bischof, Katarina Cisarova, Sandra Burgstaller, Mia Schwerer, Markus Absenger‐Novak, Philipp J. Jost, Roland Malli, Wolfgang F. Graier, Robert Lukowski   +8 more
wiley   +1 more source

Circulating Musclin is associated with skeletal muscle function and subclinical cardiac dysfunction in patients with cancer

British Journal of Pharmacology, EarlyView.
Background and Purpose Musclin (osteocrin) is a skeletal muscle‐derived peptide that has been implicated in cardioprotective signalling pathways. Its relevance in cancer patients, who frequently experience muscle wasting and cardiotoxicity, remains unclear. This study aimed to determine whether circulating Musclin levels reflect functional capacity and
Jannek Brauer, Daniel Finke, Sebastian Romann, Norbert Frey, Joerg Heineke, Lorenz H. Lehmann   +5 more
wiley   +1 more source