Results 151 to 160 of about 87,999 (333)
Background and Purpose Maternal hypoxia is a recognised risk factor for neurodevelopmental disorders in offspring. Although rodent models of hypoxia have been reported, the detailed pathogenesis of maternal hypoxia‐induced neurodevelopmental disorders remains unclear.
Kentaro Tokudome +6 more
wiley +1 more source
BJP volume 162 issue 6 Cover and Back matter [PDF]
Jack Gorman +99 more
openalex +1 more source
Abstract Background and Purpose The absence of the protein dystrophin in Duchenne muscular dystrophy (DMD) leads to progressive muscle weakness, failing regeneration and deregulation of nitric oxide (NO) signalling. We focused on L‐citrulline, a precursor of L‐arginine, required for NO production in muscle, which is reduced in dystrophic mdx muscle ...
Lisamaura Tulimiero +14 more
wiley +1 more source
BJP volume 151 issue 1 Cover and Front matter [PDF]
Mander Whirfield +10 more
openalex +1 more source
Background and Purpose The pathogenesis of type 2 diabetes mellitus (T2DM)‐induced cardiomyopathy involves cardiac fibrosis that leads to diastolic dysfunction. We established that replacement of lost substance P (SP) that occurs in T2DM reduces cardiac fibrosis and decreases inflammation in T2DM mice and non‐human primates.
Alexander Widiapradja +11 more
wiley +1 more source
As China’s only non-core K-12 science subject, astronomy education faces resource constraints. Beijing Planetarium (BJP), home to the Chinese Astronomical Society Popularization Committee, addresses this through tiered programs.
Chong Feng +6 more
doaj +1 more source
The metalloproteinase ADAM17 promotes acute lung inflammatory responses during pancreatitis
Background and Purpose Acute pancreatitis (AP) is a multifactorial upper gastrointestinal inflammatory disorder that in severe cases (~20% of all AP) is associated with substantial morbidity and mortality, the latter coincident with multiorgan dysfunction, particularly acute lung injury (ALI).
Shermin Chan +17 more
wiley +1 more source
BJP volume 149 issue 1 Cover and Back matter [PDF]
Richard Winslow +8 more
openalex +1 more source
Background and Purpose Local anaesthetics and class I anti‐arrhythmic drugs block voltage‐gated Na+ channels, but the molecular basis for the isoform differences in drug sensitivity remains unclear. Understanding these mechanisms is essential for optimizing therapeutic efficacy and safety.
Tatsuo Munakata +4 more
wiley +1 more source

