A Phase I/II Study of Ibrutinib Plus Trastuzumab in HER2‐Positive Metastatic Breast Cancer
ABSTRACT Ibrutinib has demonstrated inhibition of ErbB/HER tyrosine kinases in preclinical models. This Phase I/II study investigated the safety, efficacy, and immunomodulatory effects of ibrutinib in combination with trastuzumab in patients with HER2‐positive metastatic breast cancer (MBC) whose disease had progressed on ado‐trastuzumab emtansine ...
Joyce O'Shaughnessy +10 more
wiley +1 more source
Why doesn't neuroimaging work in psychiatry? [PDF]
McCutcheon RA, Jauhar S, Pillinger T.
europepmc +1 more source
ABSTRACT Dyslexia can negatively affect attitudes such as self‐concept, emotions and coping. Prior research has mainly focused on global academic self‐concept and negative emotions, with limited focus on specific reading‐ and spelling‐related self‐concept, positive emotions and coping strategies.
Judi E. Dams +4 more
wiley +1 more source
How language, culture, and geography shape online dialogue: Insights from Koo. [PDF]
Mekacher A, Falkenberg M, Baronchelli A.
europepmc +1 more source
Calibration of Retrospective and Prospective Life Satisfaction Judgments Around the World
ABSTRACT It is both a physical and psychological fact that humans have access to records of the past but not to records of the future. Due to this epistemic asymmetry in time, we hypothesized that retrospection about past psychological states will be better calibrated than prospection about future psychological states.
David R. Mandel +2 more
wiley +1 more source
Endocytic protein AP180 assembly domain regulates synaptic vesicle size and release in Caenorhabditis elegans. [PDF]
Wang Y +6 more
europepmc +1 more source
Precision psychiatry: thinking beyond simple prediction models - enhancing causal predictions: commentary, Seyedsalehi et al. [PDF]
Seyedsalehi A, Scola G, Fazel S.
europepmc +1 more source
Technical Debt Management in Continuous Software Engineering: State of the Art and Research Agenda
ABSTRACT Software companies have streamlined their engineering processes, and continuous development has been key to achieving flexible, market‐driven software solutions. Continuous software engineering (CSE) emerged as an approach to iteratively develop and maintain software, integrating business strategy, development, and operations aligned with ...
Lucas Carvalho +4 more
wiley +1 more source
A novel mitovirus associated with the fungal entomopathogen Zoophthora radicans. [PDF]
Adler MJ +3 more
europepmc +1 more source
Read the free Plain Language Summary for this article on the Journal blog. Abstract Home‐Field Advantage (HFA) theory—positing that litter decomposes faster at its site of origin—allows us to disentangle the respective influences of litter quality, soil biota composition, and microclimate on shifts in litter decomposition following land use conversion.
Marie Sauvadet +8 more
wiley +1 more source

