Results 191 to 200 of about 21,639 (283)

Redox‐Neutral C(sp3)─H Alkenylation via Photocatalyzed Tandem Hydrogen Atom Transfer and Downstream Oxidative Radical Polar Crossover

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 21, 3 November 2026.
Herein, we present a photocatalytic route exploiting a redox‐neutral tandem hydrogen atom transfer and oxidative radical polar crossover manifold. This method enables the synthesis of allylic amides and ethers from feedstock chemicals, showing broad functional group tolerance, mild conditions, and efficient scalability.
Mattia Lepori   +4 more
wiley   +1 more source

From CXR to ultrasound: a multi-framework approach to advancing De-implementation in acute care. [PDF]

open access: yesImplement Sci Commun
Ablordeppey EA   +6 more
europepmc   +1 more source

Clinical, Histologic, and Serological Predictors of Renal Function Loss in Lupus Nephritis

open access: yesArthritis Care &Research, Volume 78, Issue 11, Page 1650-1662, November 2026.
Objective Kidney survival is the ultimate goal in lupus nephritis (LN) management, but long‐term predictors remain inadequately studied, requiring long‐term follow‐up. This study aimed to identify baseline and early longitudinal predictors of kidney survival in the Accelerating Medicines Partnership LN longitudinal cohort.
Shangzhu Zhang   +21 more
wiley   +1 more source

Impact of COVID‐19 Restrictions on Estimating Causal Effects: Fluoroquinolones and Tendon Rupture

open access: yesPharmacoepidemiology and Drug Safety, Volume 35, Issue 11, November 2026.
ABSTRACT Purpose The COVID‐19 pandemic disrupted healthcare services, potentially affecting causal effect estimation using real‐world data. As a case study, we replicated a cohort study using Clinical Practice Research Datalink Aurum to evaluate whether pandemic‐related disruptions influenced the measured association between fluoroquinolone use and ...
Angel Y. S. Wong   +7 more
wiley   +1 more source

Novel Approach to Rule-Out Unnecessary Urine Bence Jones Protein Testing: A Serum Free Light Chain Algorithm. [PDF]

open access: yesDiagnostics (Basel)
García Moreira V   +10 more
europepmc   +1 more source

Direct evidence implicating the asymmetrical dimethylarginine (ADMA)‐dimethylarginine dimethylaminohydrolase 1 (DDAH1) pathway in cerebrovascular dysfunction and stroke pathogenesis in mice

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 21, Page 6422-6443, November 2026.
Abstract Background and Purpose Asymmetrical dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthase (NOS), whereas dimethylaminohydrolase 1 (DDAH1) is primarily responsible for its metabolism. However, the roles of DDAH1 in cerebrovascular regulation are poorly understood. Furthermore, despite evidence that elevated ADMA levels are
Arun Flynn   +10 more
wiley   +1 more source

A covalent peptide engager approach to equip immunotherapeutic monoclonal and pan IgG serum antibodies with new tumour‐targeting function

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 22, Page 6685-6703, November 2026.
Abstract Background and Purpose Site‐specific antibody modification is a useful chemical strategy to elaborate antibody therapeutic function. Conventional lysine‐ or cysteine‐based conjugation methods generate heterogeneous products, while protein engineering approaches are resource‐intensive.
Karolina Krygier   +2 more
wiley   +1 more source

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