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Optimizing the Immunosuppression: Role of Early BK Polyomavirus Surveillance and Evolving a Cost-Effective Strategy. [PDF]
Indian J NephrolSubbiah AK, Mahajan S.
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Comments on: The Second International Consensus Guidelines on the Management of BK Polyomavirus in Kidney Transplantation. [PDF]
TransplantationPham PT, Pham PT.
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BK polyomavirus: emerging pathogen [PDF]
Microbes and Infection, 2012 BK polyomavirus (BKPyV) is a small double-stranded DNA virus that is an emerging pathogen in immunocompromised individuals. BKPyV is widespread in the general population, but primarily causes disease when immune suppression leads to reactivation of latent virus.
Michael Imperiale
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Clinical Infectious Diseases, 2022
To the editor—BK polyomavirus (BKPyV) continues to challenge kidney transplantation (KT) outcomes with premature renal allograft failure, and evidence-based treatment approaches based on randomized clinical trials are sorely lacking. Imlay and coauthors [1] address this unmet need and note that “definitions of proven disease are variable.” The ...
Hirsch, Hans +2 more
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To the editor—BK polyomavirus (BKPyV) continues to challenge kidney transplantation (KT) outcomes with premature renal allograft failure, and evidence-based treatment approaches based on randomized clinical trials are sorely lacking. Imlay and coauthors [1] address this unmet need and note that “definitions of proven disease are variable.” The ...
Hirsch, Hans +2 more
openaire +3 more sources
Antivirals for the treatment of polyomavirus BK replication
Expert Review of Anti-Infective Therapy, 2007Antiviral drugs with specific activity against polyomavirus replication have not been developed in the past. This deficiency has become fully apparent with the emergence of polyomavirus-associated nephropathy in kidney-transplant recipients, with a prevalence rate of up to 10%. In most cases, high BK virus replication in tubular epithelial cells causes
Christine Hanssen Rinaldo, Hans H Hirsch
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The Lancet Infectious Diseases, 2003
Polyomavirus hominis 1, better known as BK virus (BKV), infects up to 90% of the general population. However, significant clinical manifestations are rare and limited to individuals with impaired immune functions. BKV has been associated with diverse entities such as haemorrhagic cystitis, ureteric stenosis, vasculopathy, pneumonitis, encephalitis ...
Hirsch HH, Steiger J
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Polyomavirus hominis 1, better known as BK virus (BKV), infects up to 90% of the general population. However, significant clinical manifestations are rare and limited to individuals with impaired immune functions. BKV has been associated with diverse entities such as haemorrhagic cystitis, ureteric stenosis, vasculopathy, pneumonitis, encephalitis ...
Hirsch HH, Steiger J
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Transplantation Proceedings, 2003
Because it is an important factor affecting renal transplant function, BK infections are significant problem in posttransplant. BK nephropathy develops in 5% of renal allograft recipients, in most cases within the first year after the procedure. The gold standard for BK nephropathy diagnosis is still immunohistochemical staining for large T antigen in ...
B, Matłosz +11 more
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Because it is an important factor affecting renal transplant function, BK infections are significant problem in posttransplant. BK nephropathy develops in 5% of renal allograft recipients, in most cases within the first year after the procedure. The gold standard for BK nephropathy diagnosis is still immunohistochemical staining for large T antigen in ...
B, Matłosz +11 more
openaire +2 more sources
Nephron, 2023
Renal transplant recipients are at increased risk for the development of a malignant neoplasm. Polyomavirus-associated urothelial carcinoma is a rare tumor that occurs in renal transplant recipients, with approximately 41 cases reported since 2002. It accounts for 27–31% of all post-transplant urothelial carcinomas and develops at an average of 8.5 ...
Sari Iwasaki +9 more
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Renal transplant recipients are at increased risk for the development of a malignant neoplasm. Polyomavirus-associated urothelial carcinoma is a rare tumor that occurs in renal transplant recipients, with approximately 41 cases reported since 2002. It accounts for 27–31% of all post-transplant urothelial carcinomas and develops at an average of 8.5 ...
Sari Iwasaki +9 more
openaire +2 more sources