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Human Polyomaviruses in Children Undergoing Transplantation, United States, 2008–2010 [PDF]
Emerging Infectious Diseases, 2012 Immunocompromised patients are at risk for disease caused by infection by some polyomaviruses. To define the prevalence of polyomaviruses in children undergoing transplantation, we collected samples from a longitudinal cohort and tested for the 9 known ...
Erica A. Siebrasse +11 more
doaj +3 more sources
Pathogenicity of Avian Polyomaviruses and Prospect of Vaccine Development
Viruses, 2022 Polyomaviruses are nonenveloped icosahedral viruses with a double-stranded circular DNA containing approximately 5000 bp and 5–6 open reading frames. In contrast to mammalian polyomaviruses (MPVs), avian polyomaviruses (APVs) exhibit high lethality and ...
Chen-Wei Wang +7 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2022 BackgroundBK polyomavirus infection results in renal allograft dysfunction, and it is important to find methods of prediction and treatment. As a regulator of host immunity, changes in the gut microbiota are associated with a variety of infections ...
Jian Zhang +6 more
doaj +1 more source
Natalizumab affects T-cell phenotype in multiple sclerosis: implications for JCV reactivation [PDF]
, 2016 The anti-CD49d monoclonal antibody natalizumab is currently an effective therapy against the relapsing-remitting form of multiple sclerosis (RRMS). Natalizumab therapeutic efficacy is limited by the reactivation of the John Cunningham polyomavirus (JCV ...
A Bellizzi +51 more
core +13 more sources
Serological cross-reactivity between Merkel cell polyomavirus and two closely related chimpanzee polyomaviruses. [PDF]
PLoS ONE, 2014 Phylogenetic analyses based on the major capsid protein sequence indicate that Merkel cell polyomavirus (MCPyV) and chimpanzee polyomaviruses (PtvPyV1, PtvPyV2), and similarly Trichodysplasia spinulosa-associated polyomavirus (TSPyV) and the orangutan ...
Jérôme T J Nicol +6 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2023 IntroductionPolyomaviruses have both structural and functional similarities with papillomaviruses. Accordingly, their role in human papillomavirus (HPV) associated malignancies has been studied with conflicting results.
Hanna K. Laine +8 more
doaj +1 more source
Identification and characterization of a polyomavirus in the thornback skate (Raja clavata)
Virology Journal, 2023 Members of the family Polyomaviridae have a circular double-stranded DNA genome that have been identified in various hosts ranging from mammals to arachnids.
Joana Abrantes +6 more
doaj +1 more source
Different behaviour of BK-virus infection in liver transplant recipients [PDF]
, 2016 Polyomavirus BK (BKV) infects up to 90% of the general population. After primary infection, occurring early during childhood, a state of non-replicative infection is established in the reno-urinary tract, without complications for immunocompetent hosts ...
MITTERHOFER, Anna Paola +3 more
core +3 more sources
Journal of Medical Case Reports, 2017 Background BK polyomavirus-associated nephropathy is an important cause of post-transplantation renal failure. We present two cases of BK polyomavirus-associated nephropathy who were submitted to contrasting strategies of clinical follow-up to BK ...
Ana Luisa Figueira Gouvêa +10 more
doaj +1 more source
PLoS ONE, 2023 BK polyomavirus-associated nephropathy occurs in kidney transplant recipients under immunosuppressive treatment. BK polyomavirus is implicated in cancer development and invasion, and case reports of renal cell carcinoma and urothelial carcinoma possibly ...
Noriaki Sato +8 more
doaj +1 more source