Results 1 to 10 of about 19,446 (161)

Polyomavirus infections and its clinical relevance in cancer patients: A Prospective Study

open access: yesJournal of Infection and Public Health, 2017
Summary: BK and JC polyomaviruses (PyV) have been demonstrated to be associated with the pathogenesis of various human cancers. We aimed to investigate the impact of BK and JC polyomavirus infections on several clinical parameters in different human ...
Samah A. Loutfy   +6 more
doaj   +3 more sources

KI and WU Polyomaviruses and CD4+ Cell Counts in HIV-1–infected Patients, Italy [PDF]

open access: yesEmerging Infectious Diseases, 2010
To investigate an association between KI and WU polyomavirus (KIPyV and WUPyV) infections and CD4+ cell counts, we tested HIV-1–positive patients and blood donors.
Muhammed Babakir-Mina   +7 more
doaj   +7 more sources

Unveiling the mediating role of immune cells in the link between pathogen infections and Hashimoto’s thyroiditis [PDF]

open access: yesJournal of International Medical Research
Background This study employed Mendelian randomization to investigate the relationships between pathogenic infections, immunophenotypes, and Hashimoto’s thyroiditis, providing deeper insights into infection-induced Hashimoto’s thyroiditis development ...
Jie Zhou   +4 more
doaj   +2 more sources

Pathogenicity of Avian Polyomaviruses and Prospect of Vaccine Development

open access: yesViruses, 2022
Polyomaviruses are nonenveloped icosahedral viruses with a double-stranded circular DNA containing approximately 5000 bp and 5–6 open reading frames. In contrast to mammalian polyomaviruses (MPVs), avian polyomaviruses (APVs) exhibit high lethality and ...
Chen-Wei Wang   +7 more
doaj   +1 more source

Modulation of Retinoic Acid Receptor Signaling Pathway via All-Trans Retinoic Acid in Merkel Cell Carcinoma Cells

open access: yesBiology and Life Sciences Forum, 2023
The biological activity of retinoic acid or all-trans retinoic acid (ATRA) is mediated by retinoic receptors, which are ligand-dependent transcription factors that activate genes crucial for cell differentiation.
John Charles Rotondo   +11 more
doaj   +1 more source

Serum Antibodies Against the Oncogenic Merkel Cell Polyomavirus Detected by an Innovative Immunological Assay With Mimotopes in Healthy Subjects

open access: yesFrontiers in Immunology, 2021
Merkel cell polyomavirus (MCPyV), a small DNA tumor virus, has been detected in Merkel cell carcinoma (MCC) and in normal tissues. Since MCPyV infection occurs in both MCC-affected patients and healthy subjects (HS), innovative immunoassays for detecting
Chiara Mazziotta   +12 more
doaj   +1 more source

Gut Microbiota Dysbiosis in BK Polyomavirus-Infected Renal Transplant Recipients: A Case-Control Study

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
BackgroundBK polyomavirus infection results in renal allograft dysfunction, and it is important to find methods of prediction and treatment. As a regulator of host immunity, changes in the gut microbiota are associated with a variety of infections ...
Jian Zhang   +6 more
doaj   +1 more source

A 10-case series of Merkel cell carcinoma in tropical Taiwan: Focusing on clinical outcomes and the interaction of oxidative stress and Merkel cell polyomavirus infections

open access: yesDermatologica Sinica, 2022
Background: There are limited data discussing Merkel cell carcinoma (MCC) clinicopathological characteristics in Asian patients. Furthermore, the association between two key pathogenic factors, ultraviolet (UV) radiation and Merkel cell polyomavirus ...
Chia-Jui Su, Jui Lan, Chih-Hung Lee
doaj   +1 more source

Hamster Polyomavirus Research: Past, Present, and Future

open access: yesViruses, 2021
Hamster polyomavirus (Mesocricetus auratus polyomavirus 1, HaPyV) was discovered as one of the first rodent polyomaviruses at the end of the 1960s in a colony of Syrian hamsters (Mesocricetus auratus) affected by skin tumors.
Burkhard Jandrig   +5 more
doaj   +1 more source

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