Results 1 to 10 of about 15,017 (178)

Polyomavirus infections and its clinical relevance in cancer patients: A Prospective Study

Journal of Infection and Public Health, 2017
Summary: BK and JC polyomaviruses (PyV) have been demonstrated to be associated with the pathogenesis of various human cancers. We aimed to investigate the impact of BK and JC polyomavirus infections on several clinical parameters in different human ...
Samah A. Loutfy, Manar M. Moneer, Salem E. Salem, Emad A. El-Moniem Abada, Entsar A. El-Moniem Ahmed, Lamiaa H. Ibrahim, EL-Chaimaa B. Mohamed   +6 more
doaj   +3 more sources

Evaluation of Trichodysplasia Spinulosa Polyomavirus in Skin Biopsies, United States [PDF]

Emerging Infectious Diseases
Trichodysplasia spinulosa polyomavirus (TSPyV) has been identified in human endothelial cell tumors. We evaluated 25 clinical cases of various inflammatory dermatoses in California, USA, for TSPyV by using RNAscope in situ hybridization.
Ivan M. Espinal, Gregory W. Charville, Lauren Lawrence, Ryanne A. Brown, Kerri E. Rieger, Sebastian Fernandez-Pol   +5 more
doaj   +2 more sources

Unveiling the mediating role of immune cells in the link between pathogen infections and Hashimoto’s thyroiditis [PDF]

Journal of International Medical Research
Background This study employed Mendelian randomization to investigate the relationships between pathogenic infections, immunophenotypes, and Hashimoto’s thyroiditis, providing deeper insights into infection-induced Hashimoto’s thyroiditis development ...
Jie Zhou, Yixin Xu, Haitao Wang, Chao Chen, Kun Wang   +4 more
doaj   +2 more sources

Pathogenicity of Avian Polyomaviruses and Prospect of Vaccine Development

Viruses, 2022
Polyomaviruses are nonenveloped icosahedral viruses with a double-stranded circular DNA containing approximately 5000 bp and 5–6 open reading frames. In contrast to mammalian polyomaviruses (MPVs), avian polyomaviruses (APVs) exhibit high lethality and ...
Chen-Wei Wang, Yung-Liang Chen, Simon J. T. Mao, Tzu-Chieh Lin, Ching-Wen Wu, Duangsuda Thongchan, Chi-Young Wang, Hung-Yi Wu   +7 more
doaj   +1 more source

Modulation of Retinoic Acid Receptor Signaling Pathway via All-Trans Retinoic Acid in Merkel Cell Carcinoma Cells

Biology and Life Sciences Forum, 2023
The biological activity of retinoic acid or all-trans retinoic acid (ATRA) is mediated by retinoic receptors, which are ligand-dependent transcription factors that activate genes crucial for cell differentiation.
John Charles Rotondo, Chiara Mazziotta, Giampaolo Morciano, Christian Felice Cervellera, Giada Badiale, Giulia Tonnini, Giulia Di Mauro, Paolo Pinton, Antoine Touzé, Pauline Gaboriaud, Mauro Tognon, Fernanda Martini   +11 more
doaj   +1 more source

Serum Antibodies Against the Oncogenic Merkel Cell Polyomavirus Detected by an Innovative Immunological Assay With Mimotopes in Healthy Subjects

Frontiers in Immunology, 2021
Merkel cell polyomavirus (MCPyV), a small DNA tumor virus, has been detected in Merkel cell carcinoma (MCC) and in normal tissues. Since MCPyV infection occurs in both MCC-affected patients and healthy subjects (HS), innovative immunoassays for detecting
Chiara Mazziotta, Carmen Lanzillotti, Elena Torreggiani, Lucia Oton-Gonzalez, Maria Rosa Iaquinta, Elisa Mazzoni, Pauline Gaboriaud, Antoine Touzé, Ettore Silvagni, Marcello Govoni, Fernanda Martini, Mauro Tognon, John Charles Rotondo   +12 more
doaj   +1 more source

Gut Microbiota Dysbiosis in BK Polyomavirus-Infected Renal Transplant Recipients: A Case-Control Study

Frontiers in Cellular and Infection Microbiology, 2022
BackgroundBK polyomavirus infection results in renal allograft dysfunction, and it is important to find methods of prediction and treatment. As a regulator of host immunity, changes in the gut microbiota are associated with a variety of infections ...
Jian Zhang, Jian Zhang, Hao Qin, Mingyu Chang, Yang Yang, Jun Lin, Jun Lin   +6 more
doaj   +1 more source

A 10-case series of Merkel cell carcinoma in tropical Taiwan: Focusing on clinical outcomes and the interaction of oxidative stress and Merkel cell polyomavirus infections

Dermatologica Sinica, 2022
Background: There are limited data discussing Merkel cell carcinoma (MCC) clinicopathological characteristics in Asian patients. Furthermore, the association between two key pathogenic factors, ultraviolet (UV) radiation and Merkel cell polyomavirus ...
Chia-Jui Su, Jui Lan, Chih-Hung Lee
doaj   +1 more source

Hamster Polyomavirus Research: Past, Present, and Future

Viruses, 2021
Hamster polyomavirus (Mesocricetus auratus polyomavirus 1, HaPyV) was discovered as one of the first rodent polyomaviruses at the end of the 1960s in a colony of Syrian hamsters (Mesocricetus auratus) affected by skin tumors.
Burkhard Jandrig, Hans Krause, Wolfgang Zimmermann, Emilija Vasiliunaite, Alma Gedvilaite, Rainer G. Ulrich   +5 more
doaj   +1 more source

Viral Genomic Characterization and Replication Pattern of Human Polyomaviruses in Kidney Transplant Recipients

Viruses, 2020
Human Polyomavirus (HPyV) infections are common, ranging from 60% to 100%. In kidney transplant (KTx) recipients, HPyVs have been associated with allograft nephropathy, progressive multifocal leukoencephalopathy, and skin cancer.
Lucia Signorini, Maria Dolci, Evaldo Favi, Caterina Colico, Mariano Ferraresso, Rosalia Ticozzi, Giuseppe Basile, Pasquale Ferrante, Serena Delbue   +8 more
doaj   +1 more source