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BK Polyomavirus—Biology, Genomic Variation and Diagnosis [PDF]
Viruses, 2021 The BK polyomavirus (BKPyV), a representative of the family Polyomaviridae, is widespread in the human population. While the virus does not cause significant clinical symptoms in immunocompetent individuals, it is activated in cases of immune deficiency,
Jacek Furmaga +2 more
exaly +5 more sources
BK polyomavirus-associated nephropathy [PDF]
Childhood Kidney Diseases, 2022 BK polyomavirus (BKPyV) is a ubiquitous virus residing in the kidney tubules and is clinically significant only in immunocompromised patients. In clinical practice, BKPyV is a causative pathogen of BKPyV-associated nephropathy (BKVAN) in kidney allograft
Yo Han Ahn, Hee Gyung Kang
doaj +2 more sources
BK Polyomavirus in Renal Transplantation: Virological Notes for Monitoring and Diagnosis [PDF]
BiomoleculesPolyomavirus-associated nephropathy was first reported over 50 years ago. However, it still represents a cause of renal injury in kidney transplant recipients, particularly in the first two years post-transplantation, with occurrence rates of 1–10%.
Cristina Costa +3 more
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A highly potent human antibody neutralizing all serotypes of BK polyomavirus. [PDF]
PLoS PathogensBK polyomavirus infection poses a significant risk to kidney transplant recipients. Reactivation of dormant virus in the transplanted kidney, triggered by immunosuppression, can lead to BK polyomavirus-associated nephropathy in up to 10% of transplants ...
Marcel Weber +12 more
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BK Polyomavirus-Associated Nephropathy and Hemorrhagic Cystitis in Transplant Recipients—What We Understand and What Remains Unclear [PDF]
VirusesThe reactivation of BK polyomavirus (BKPyV) during severe immunosuppression plays a crucial role in two significant syndromes observed in transplant recipients: BK polyomavirus-associated nephropathy (BKPyVAN) in kidney transplant patients and BK ...
Tang-Her Jaing +2 more
doaj +2 more sources
Development of a droplet digital PCR assay for the detection of BK polyomavirus [PDF]
Microbiology SpectrumThe objective of this study was to establish a more sensitive and specific diagnostic method for detecting plasma BK polyomavirus (BKPyV) DNA load in patients after renal transplantation using droplet digital polymerase chain reaction (ddPCR) and to ...
Lu Ai +9 more
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Frontiers in Cellular and Infection Microbiology, 2022 BackgroundBK polyomavirus infection results in renal allograft dysfunction, and it is important to find methods of prediction and treatment. As a regulator of host immunity, changes in the gut microbiota are associated with a variety of infections ...
Jian Zhang +6 more
doaj +1 more source
PLoS ONE, 2023 BK polyomavirus-associated nephropathy occurs in kidney transplant recipients under immunosuppressive treatment. BK polyomavirus is implicated in cancer development and invasion, and case reports of renal cell carcinoma and urothelial carcinoma possibly ...
Noriaki Sato +8 more
doaj +1 more source
Transplantation Reports, 2021 Introduction: : BK polyoma virus nephropathy represents one of the non-immunological causes of renal graft loss with a cumulative incidence between 5 and 10 percent, and a graft loss rate on BK virus nephropathy patients that ranges from 30 to 90 percent
Rodolfo Torres +7 more
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Native BK Polyomavirus Nephropathy in an Orthotopic Heart Transplant Patient
Journal of Investigative Medicine High Impact Case Reports, 2023 BK polyomavirus nephropathy (BKVN) is a common cause of nephropathy in kidney transplant patients and is typically seen within the first year after transplantation.
Zachary M. Thompson MD +5 more
doaj +1 more source