Results 31 to 40 of about 10,884 (222)
The Potential Role of BK and JC Polyomaviruses in Urothelial Cancer
The Iraqi Journal of Medical SciencesBackground: BK and JC polyomaviruses are perceived as the two most common human polyomaviruses (HPyVs). These two viruses inhabit the epithelial surfaces of the bladder and kidney as the primary site of replication and latency.
Kawther A. AlMalaki +2 more
doaj +3 more sources
Natalizumab affects T-cell phenotype in multiple sclerosis: implications for JCV reactivation [PDF]
, 2016 The anti-CD49d monoclonal antibody natalizumab is currently an effective therapy against the relapsing-remitting form of multiple sclerosis (RRMS). Natalizumab therapeutic efficacy is limited by the reactivation of the John Cunningham polyomavirus (JCV ...
A Bellizzi +51 more
core +8 more sources
Polyomavirus infections and its clinical relevance in cancer patients: A Prospective Study
Journal of Infection and Public Health, 2017 Summary: BK and JC polyomaviruses (PyV) have been demonstrated to be associated with the pathogenesis of various human cancers. We aimed to investigate the impact of BK and JC polyomavirus infections on several clinical parameters in different human ...
Samah A. Loutfy +6 more
doaj +1 more source
A Cell Culture Model of BK Polyomavirus Persistence, Genome Recombination, and Reactivation
mBio, 2021 BK polyomavirus (BKPyV) generally establishes a persistent subclinical infection in healthy individuals but can cause severe disease in transplant recipients.
Linbo Zhao, Michael J. Imperiale
doaj +1 more source
No Evidence of Human Polyomavirus 9, WU and KI DNA in Kidney and Urinary Bladder Tumour Tissue Samples [PDF]
, 2016 KAL
Bidiga, László +3 more
core +1 more source
Frontiers in Medicine, 2023 BackgroundBK polyomavirus replication leads to progressive tubulointerstitial nephritis and ureteral stenosis, with a considerable risk of subsequent graft failure in kidney transplant recipients. Since specific antiviral therapies are lacking, new tools
Kenza Zoubir +14 more
doaj +1 more source
Posoleucel for BK Polyomavirus in Kidney Transplant Recipients. [PDF]
J Am Soc NephrolWilhelm M, Geng A, Schaub S, Hirsch HH.
europepmc +3 more sources
BK polyomavirus—pathogen, paradigm and puzzle
Nephrology Dialysis Transplantation, 2019 AbstractBK virus is a polyomavirus with seroprevalence rates of 80% in adults. Infection is usually acquired during childhood, and the virus is benign or pathologic depending on immune status. The virus reactivates in immunodeficiency states, mostly among transplant (either kidney or bone marrow) recipients.
Suman Krishna Kotla +3 more
openaire +2 more sources
BK polyomavirus: latency, reactivation, diseases and tumorigenesis
Frontiers in Cellular and Infection Microbiology, 2023 The identification of the first human polyomavirus BK (BKV) has been over half century, The previous epidemiological and phylogenetic studies suggest that BKV prevailed and co-evolved with humans, leading to high seroprevalence all over the world. In general, BKV stays latent and symptomless reactivation in healthy individuals.
Xianfeng Zhou +4 more
openaire +3 more sources
Kaohsiung Journal of Medical Sciences, 2016 Previous studies regarding the prevention of BK viremia following renal transplantation with fluoroquinolone have yielded conflicting results. The purpose of this systematic review was to examine the evidence regarding the efficacy of fluoroquinolone in ...
Tu-Run Song +6 more
doaj +1 more source