Results 31 to 40 of about 81,224 (208)

BKV Agnoprotein Interacts with α-Soluble N-Ethylmaleimide-Sensitive Fusion Attachment Protein, and Negatively Influences Transport of VSVG-EGFP [PDF]

, 2011
Background: The human polyomavirus BK (BKV) infects humans worldwide and establishes a persistent infection in the kidney. The BK virus genome encodes three regulatory proteins, large and small tumor-antigen and the agnoprotein, as well as the capsid ...
Johannessen, M., Mona Johannessen, Walquist, Mari, Moens, Ugo, Walquist Mari, Spang Anne, Mari Walquist, Moens Ugo, Anne Spang, Gerits, N., Spang, Anne, Johannessen, Mona, Marte Dragset, Gerits Nancy, Johannessen Mona, Nancy Gerits, Ugo Moens, Dragset Marte, Walquist, M., Gerits, Nancy, Dragset, Marte Singsås, Dragset, M., Spang, A., Moens, U.   +23 more
core   +1 more source

Should SVGp12 Be Used for JC Polyomavirus Studies? Comment on Prezioso et al. COS-7 and SVGp12 Cellular Models to Study JCPyV Replication and MicroRNA Expression after Infection with Archetypal and Rearranged-NCCR Viral Strains. Viruses 2022, 14, 2070

Viruses, 2022
A recent paper in Viruses investigates the impact of the JC polyomavirus (JCPyV) microRNA on the replication of different JCPyV strains. Unfortunately, one of the cell lines used, the human fetal glial cell line SVGp12, is productively infected by the ...
Stian Henriksen, Christine Hanssen Rinaldo   +1 more
doaj   +1 more source

BK Polyomavirus and the Transplanted Kidney [PDF]

Transplantation, 2016
BK polyomavirus is ubiquitous, with a seropositivity rate of over 75% in the adult population. Primary infection is thought to occur in the respiratory tract, but asymptomatic BK virus latency is established in the urothelium. In immunocompromised host, the virus can reactivate but rarely compromises kidney function except in renal grafts, where it ...
Lamarche, Caroline, Orio, Julie, Collette, Suzon, Senécal, Lynne, Hébert, Marie-Josée, Renoult, Édith, Tibbles, Lee Anne, Delisle, Jean-Sébastien   +7 more
openaire   +2 more sources

Persistently high-level polyomavirus BK replication in the absence of renal function abnormalities in a kidney transplant recipient

Microbiologia Medica, 2016
Polyomavirus-associated nephropathy is an important cause of allograft dysfunction and graft loss after kidney transplantation. Even if histological evaluation is the gold standard for graft study and diagnosis of polyomavirus-associated nephropathy, K ...
Antonio Curtoni, Cristina Costa, Maria Messina, Francesca Sidoti, Andrea Piceghello, Gabriele Bianco, Luigi Biancone, Giuseppe Paolo Segoloni, Rossana Cavallo   +8 more
doaj   +1 more source

Research progress in BK polyomavirus nephropathy [PDF]

Jichu yixue yu linchuang
BK polyomavirus (BKPyV) typically enters host cells through caveolin-mediated endocytosis or clathrin-independent vesicle encapsulation, maintaining clinical latency without symptomatic manifestations.
YANG Dan, YANG Feng
doaj   +1 more source

The Potential Role of BK and JC Polyomaviruses in Urothelial Cancer

The Iraqi Journal of Medical Sciences
Background:    BK and JC polyomaviruses are perceived as the two most common human polyomaviruses (HPyVs). These two viruses inhabit the epithelial surfaces of the bladder and kidney as the primary site of replication and latency.
Kawther A. AlMalaki, Asmaa' B. Al-Obaidi, Haider F. Ghazi   +2 more
doaj   +3 more sources

Polyomavirus infections and its clinical relevance in cancer patients: A Prospective Study

Journal of Infection and Public Health, 2017
Summary: BK and JC polyomaviruses (PyV) have been demonstrated to be associated with the pathogenesis of various human cancers. We aimed to investigate the impact of BK and JC polyomavirus infections on several clinical parameters in different human ...
Samah A. Loutfy, Manar M. Moneer, Salem E. Salem, Emad A. El-Moniem Abada, Entsar A. El-Moniem Ahmed, Lamiaa H. Ibrahim, EL-Chaimaa B. Mohamed   +6 more
doaj   +1 more source

A Cell Culture Model of BK Polyomavirus Persistence, Genome Recombination, and Reactivation

mBio, 2021
BK polyomavirus (BKPyV) generally establishes a persistent subclinical infection in healthy individuals but can cause severe disease in transplant recipients.
Linbo Zhao, Michael J. Imperiale
doaj   +1 more source

Molecular Evaluation of BK Polyomavirus Nephropathy

American Journal of Transplantation, 2005
Understanding at a molecular level, the immunologic response of polyomavirus nephropathy (PVN), a critical cause of kidney graft loss, could lead to new targets for treatment and diagnosis. We undertook a transcriptional evaluation of kidney allograft biopsies from recipients with PVN or acute rejection (AR), as well as from recipients with stable ...
R B, Mannon, S C, Hoffmann, R L, Kampen, O C, Cheng, D E, Kleiner, C, Ryschkewitsch, B, Curfman, E, Major, D A, Hale, A D, Kirk   +9 more
openaire   +2 more sources

The potential therapeutic usefulness of targeting bk polyomavirus in prostate cancer [PDF]

, 2015
Prostate cancer (PCa) is a slow-growing, organ-confined tumor usually accompanied with a favorable overall prognosis. Current standard-of-care chemotherapy, and recently immunotherapies, for patients suffering from this disease may prolong overall ...
Keller, Etienne Xavier, Provenzano, Maurizio; https://orcid.org/   +1 more
core   +1 more source