Results 51 to 60 of about 10,884 (222)
Exposing the Molecular Machinery of BK Polyomavirus [PDF]
Structure, 2016 BK polyomavirus (BKV) is an opportunistic pathogen that poses a serious threat to organ transplant recipients. In this issue of Structure, Hurdiss and colleagues' (Hurdiss et al., 2016) beautiful new high-resolution cryo-EM reconstruction of BKV provides a structural roadmap for the ongoing development of therapeutic antibodies and vaccines targeting ...
openaire +2 more sources
Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?
Medicinal Research Reviews, EarlyView.ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca +6 more
wiley +1 more source
Identification of the novel KI polyomavirus in paranasal and lung tissues [PDF]
, 2009 KI is a novel polyomavirus identified in the respiratory secretions of children with acute respiratory symptoms. Whether this reflects a causal role of the virus in the human respiratory disease remains to be established.
Aquaro, S +5 more
core +1 more source
Organ Medicine, EarlyView.This review evaluates how machine learning, multimodal integration, and generative AI optimize kidney transplant outcomes. These tools enable superior prediction and personalized therapy but face hurdles in data volume, generalizability, and ethics. Future clinical adoption depends on continued innovation and multidisciplinary collaboration to overcome
Maoxin Liao, Cheng Yang
wiley +1 more source
BK viremia in critically ill surgical patients with hemorrhagic or septic shock [PDF]
, 2012 Background Infections with polyomavirus BK virus (BKV) are a common cause of renal dysfunction after renal transplantation and may also be harmful in surgical patients with shock.
Benedikt Weissbrich +4 more
core +2 more sources
Paediatric renal transplantation: Paediatric surgeons' perspective
Surgical Practice, EarlyView.Abstract Renal transplantation is the most effective treatment for paediatric end‐stage renal disease (ESRD), offering advantages in survival, growth and neurocognitive development that surpass other renal replacement therapies (RRT). The paediatric setting, however, introduces distinct complexities that distinguish it from adult practice.
Adrian Chi‐heng Fung +3 more
wiley +1 more source
Annals of Hepatology, 2015 Renal dysfunction frequently occurs in liver transplant recipients and is associated with increased morbidity and mortality. BK virus is a human polyoma virus that reactivates during immunocompromised states and is a known cause of renal allograft ...
Yangmin Zeng +6 more
doaj +1 more source
Absence of DNA viruses in ameloblastomas
European Journal of Oral Sciences, EarlyView.Abstract Ameloblastomas (ABs) are rare odontogenic benign tumors. Although studies of the molecular pathogenesis have revealed the presence of mutations and altered gene expression, the etiology is unresolved. Viruses cause 10%–15 % of cancers, but their potential role within benign tumors is less studied.
Maria K. Jauhiainen +5 more
wiley +1 more source
Viruses, 2021 Over-immunosuppressed kidney transplant recipients are susceptible to malignancies and BK polyomavirus (BKPyV)-associated nephropathy (BKPyVAN). This study aimed to verify the association between BKPyV infection and urinary tract cancers (UTC).
Yi-Jung Li +8 more
doaj +1 more source
BK virus infection, replication, and diseases in pediatric kidney transplantation [PDF]
, 2018 Polyomavirus-associated nephropathy is diagnosed in 2-8% of pediatric renal transplants and often precedes renal allograft dysfunction. Without intervention, however, significant graft dysfunction is observed in more than 50% of cases, although ...
Acott, Philip, Hirsch, Hans
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