Efficacy and Safety of Ciprofloxacin for Prophylaxis of Polyomavirus BK Virus–Associated Hemorrhagic Cystitis in Allogeneic Hematopoietic Stem Cell Transplantation Recipients [PDF]
Polyoma virus BK–induced hemorrhagic cystitis is an important cause of morbidity after hematopoietic stem cell transplantation (HSCT). Fluoroquinolones have been shown in vitro to inhibit BK viral replication by direct inhibition of the BK-encoded DNA ...
Bowd, Kathryn +9 more
core +2 more sources
The human polyomavirus BK: Potential role in cancer [PDF]
AbstractIn human cancer, a role has been suggested for the human polyomavirus BK, primarily associated with tubulointerstitial nephritis and ureteric stenosis in renal transplant recipients, and with hemorrhagic cystitis in bone marrow transplant (BMT) recipients.
FIORITI, DANIELA +6 more
openaire +5 more sources
Beyond Human Papillomavirus (HPV): Detection of EBV and Polyomaviruses in Cervical and Anal Samples
ABSTRACT Colorectal and cervical cancers represent an important public health problem worldwide, particularly in Brazil. Colorectal cancer is one of the most frequently diagnosed malignancies worldwide and the most common cancer in both men and woman in Brazil.
Ana Carolina Silva Guimarães +11 more
wiley +1 more source
BK POLYOMAVIRUS-INFECTED DECOY CELLS IN URINE CYTOLOGY SPECIMENS OF RENAL TRANSPLANT RECIPIENTS
Background:BK polyomavirus is one of the common post-transplant viral infections, affecting ?15% of renal transplantation recipients (RTR), leading to graft loss in more than half of cases.
Asmaa B. Al-Obaidi +6 more
doaj +4 more sources
In pursuit of therapeutics for human polyomaviruses, we identified a peptide derived from the BK polyomavirus (BKV) minor structural proteins VP2/3 that is a potent inhibitor of BKV infection with no observable cellular toxicity.
Joshua R Kane +12 more
doaj +1 more source
Ureteral stent placement increases the risk for developing BK viremia after kidney transplantation. [PDF]
The placement of ureteral stent (UrSt) at kidney transplantation reduces major urological complications but increases the risk for developing nephropathy from the BK virus.
Dharnidharka, Vikas R +3 more
core +4 more sources
BK virus‐associated urothelial carcinoma—A supra‐regional cohort of kidney transplant recipients
Abstract Objectives This study aims to study the clinical features, pathological findings, and outcomes of BK virus‐associated urothelial carcinoma (UC) in kidney transplant recipients (KTRs). Patients and Methods The study was conducted in a retrospective cohort of KTRs with histologically confirmed UC managed at a UK supra‐regional transplant urology
Noah Beetge +4 more
wiley +1 more source
Cytomegalovirus and polyomavirus BK posttransplant [PDF]
Virus replication and progression to disease in transplant patients is determined by patient-, graft- and virus-specific factors. This complex interaction is modulated by the net state of immunosuppression and its impact on virus-specific cellular ...
Binggeli, Simone +8 more
core
Production of recombinant VP1-derived virus-like particles from novel human polyomaviruses in yeast [PDF]
Background: Eleven new human polyomaviruses (HPyVs) have been identified in the last decade. Serological studies show that these novel HPyVs sub-clinically infect humans at an early age.
Alma Gedvilaite +5 more
core +1 more source
Control of Archetype BK Polyomavirus MicroRNA Expression
The BK polyomavirus (BKPyV) miRNA plays an important role in regulating viral large-T-antigen expression and limiting the replication of archetype BKPyV, suggesting that the miRNA regulates BKPyV persistence. However, how miRNA expression is regulated is poorly understood.
Wei Zou +5 more
openaire +3 more sources

