Results 61 to 70 of about 81,224 (208)

Polyomavirus Drives Cerebellar Lesions in AIDS Monkeys With Ataxia

MedComm, Volume 7, Issue 11, November 2026.
Chronic SIV‐infected macaques with ataxia develop severe cerebellar lesions driven by simian polyomavirus 40 (SV40) infection. SV40 preferentially infects cerebellar granule cells, inducing pyroptosis and an aberrant proliferative state. Pyroptotic neuronal injury promotes microglial recruitment and activation, amplifying local neuroinflammation and ...
Tian‐Zhang Song, Li‐Rong Zhang, Yun‐Mei Wang, Yan Hu, Qing Li, Ren‐Rong Tian, Liu‐Meng Yang, Si‐Dong Xiong, Dong‐Dong Wu, Yong‐Tang Zheng   +9 more
wiley   +1 more source

High Incidence and Early Onset of Urinary Tract Cancers in Patients with BK Polyomavirus Associated Nephropathy

Viruses, 2021
Over-immunosuppressed kidney transplant recipients are susceptible to malignancies and BK polyomavirus (BKPyV)-associated nephropathy (BKPyVAN). This study aimed to verify the association between BKPyV infection and urinary tract cancers (UTC).
Yi-Jung Li, Hsin-Hsu Wu, Cheng-Hsu Chen, Hsu-Han Wang, Yang-Jen Chiang, Hsiang-Hao Hsu, See-Tong Pang, Robert Y. L. Wang, Ya-Chung Tian   +8 more
doaj   +1 more source

T‐Cell Remodeling in Renal Fibrosis: From Acute Injury to Chronic Kidney Disease

Advanced Science, Volume 13, Issue 58, 19 October 2026.
This Review presents renal fibrosis as a sequence of overlapping T‐cell programs, from chemokine‐guided recruitment and metabolic activation to maladaptive polarization, tertiary lymphoid structure formation, tissue residency, exhaustion, and senescence.
Qianhui Li, Junting Guan, Yifan Song, Hongxia Yang, Guangtao Li, Xiaodong Zhao, Jiaxin Liu, Bin Liu, Yang Tan, Honglan Zhou, Yang‐He Zhang, Yishu Wang   +11 more
wiley   +1 more source

Cross‐Neutralizing and Broadly Neutralizing Human Antibodies Against Nonenveloped Viruses

European Journal of Immunology, Volume 56, Issue 10, October 2026.
In this review article, Marchand et al. compare cross ‐ and broadly ‐neutralizing human antibodies against non ‐ enveloped viruses from several major families, discussing their structural characteristics, neutralization mechanisms and relevance for the development of antiviral vaccines and therapeutics.
Sarah Marchand, Samy Taouli, Dorian McIlroy   +2 more
wiley   +1 more source

BK Polyomavirus in Renal Transplantation [PDF]

General Medicine: Open Access, 2014
BK virus is a human polyomavirus that rarely causes disease, except in immune-compromised patients. Evidence of prior BK Virus (BKV) infection is highly prevalent in the general population, and although it rarely causes significant morbidity at primary infection, reactivation of BKV after kidney transplantation is recognized as a cause of BKV ...
openaire   +1 more source

Frequency of Polyomavirus BK Infection in Kidney Transplant Patients Suspected to Nephropathy

International Journal of Organ Transplantation Medicine, 2015
Background: Polyomavirus BK is a major cause of nephropathy in immunosuppressed transplanted patients. Non-invasive diagnostic protocols such as molecular detection of polyomavirus BK replication are a useful strategy to predict BK virus-associated ...
M Pakfetrat, R Yaghobi, Z Salmanpoor, J Roozbeh, S Torabinezhad, S Kadkhodaei   +5 more
doaj  

Conversion from mycophenolate mofetil to mizoribine in the early stages of BK polyomavirus infection could improve kidney allograft prognosis: a single-center study from China

BMC Nephrology, 2021
Background Some studies have suggested mizoribine (MZR) could inhibit the replication of BK polyomavirus (BKPyV). The purpose of this study was to explore whether conversion from mycophenolate mofetil (MMF) to MZR in the early stages of BKPyV infection ...
Ping Li, Dongrui Cheng, Jiqiu Wen, Xuefeng Ni, Kenan Xie, Xue Li, Jinsong Chen   +6 more
doaj   +1 more source

Belatacept Conversion in Simultaneous Pancreas‐Kidney and Liver‐Kidney Transplant Recipients: A Single‐Center Feasibility Cohort and Narrative Review

Clinical Transplantation, Volume 40, Issue 10, October 2026.
ABSTRACT Background Calcineurin inhibitor (CNI) nephrotoxicity drives long‐term kidney‐function decline after simultaneous pancreas‐kidney (SPK) and liver‐kidney (LK) transplantation, but belatacept conversion, as an alternative strategy, is poorly studied in these recipients, whose non‐kidney allograft rejection risk differs.
Dusan Harmacek, Elena Rho, Seraina von Moos, Severin Simmler, Thomas Welte, Fabian Rössler, Thomas Schachtner, Lukas Weidmann   +7 more
wiley   +1 more source

Desenvolvimento e aplicação de um sistema celular repórter para herpes simplex virus e padronização de uma PCR quantitativa para poliomavírus BK [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Biotecnologia e Biociências, Florianópolis, 2014.Pacientes imunodeprimidos podem apresentar infecções virais com evolução rápida,
Feltrin, Clarissa
core  

Agnoprotein Is an Essential Egress Factor during BK Polyomavirus Infection [PDF]

, 2018
BK polyomavirus (BKPyV; hereafter referred to as BK) causes a lifelong chronic infection and is associated with debilitating disease in kidney transplant recipients. Despite its importance, aspects of the virus life cycle remain poorly understood.
Hollinshead, M, Panou, M-M, Colin Crump, Andrew Macdonald, Louisa Carlisle, Laura Caller, Ethan Morgan, Gemma Swinscoe, Hurdiss, DL, Crump, CM, Caller, LG, Kealy, D, Daniel Hurdiss, Macdonald, A, Swinscoe, G, Marietta Müller, Antoni, M, Morgan, EL, Carlisle, L, Neil Ranson, Müller, M, Michelle Antoni, Prescott, EL, Ranson, NA, Michael Hollinshead, Emma Prescott, Margarita-Maria Panou, David Kealy   +27 more
core   +3 more sources