Results 1 to 10 of about 2,684 (148)

High Incidence and Early Onset of Urinary Tract Cancers in Patients with BK Polyomavirus Associated Nephropathy [PDF]

Viruses, 2021
Over-immunosuppressed kidney transplant recipients are susceptible to malignancies and BK polyomavirus (BKPyV)-associated nephropathy (BKPyVAN). This study aimed to verify the association between BKPyV infection and urinary tract cancers (UTC).
Hsiang-Hao Hsu, Hsin Hsu Wu, Ya-Chung Tian   +2 more
exaly   +7 more sources

Exploring the mechanism of BK polyomavirus-associated nephropathy through consensus gene network approach. [PDF]

PLoS ONE, 2023
BK polyomavirus-associated nephropathy occurs in kidney transplant recipients under immunosuppressive treatment. BK polyomavirus is implicated in cancer development and invasion, and case reports of renal cell carcinoma and urothelial carcinoma possibly ...
Noriaki Sato, Keita P Mori, Kaoru Sakai, Hitomi Miyata, Shinya Yamamoto, Takashi Kobayashi, Hironori Haga, Motoko Yanagita, Yasushi Okuno   +8 more
doaj   +4 more sources

Incidence, Risk Factors, and Outcomes of Kidney Transplant Recipients With BK Polyomavirus-Associated Nephropathy [PDF]

Kidney International Reports, 2023
BK polyomavirus-associated nephropathy (BKPyVAN) is associated with graft dysfunction and loss; however, knowledge of immunosuppression reduction strategies and long-term graft, and patient outcomes across the disease spectrum is lacking.This cohort study included 14,697 kidney transplant recipients in Australia and New Zealand (2005-2019), followed ...
David Johnson, Germaine Wong, Philip Clayton   +2 more
exaly   +6 more sources

Development of BK polyomavirus-associated nephropathy risk prediction in kidney transplant recipients [PDF]

Renal Failure
Background With the development of potential prevention therapies for BK polyomavirus (BKPyV)-associated nephropathy (BKPyVAN), risk prediction models are needed to identify kidney transplant recipients at high risk for BKPyVAN.Methods This single-center
Junji Yamauchi, Katalin Fornadi, Divya Raghavan, Duha Jweehan, Suayp Oygen, Silviana Marineci, Michelle Buff, Michael Fenlon, Motaz Selim, Michael Zimmerman, Miklos Z. Molnar   +10 more
doaj   +4 more sources

Innate Immunity Response to BK Virus Infection in Polyomavirus-Associated Nephropathy in Kidney Transplant Recipients [PDF]

Transplantology, 2022
BK polyomavirus (BKV) mainly causes infection in uroepithelial and renal tubular epithelial cells of either immunocompetent or immunocompromised hosts.
Wiwat Chancharoenthana, Asada Leelahavanichkul, Leelahavanichkul Asada   +2 more
exaly   +4 more sources

BK Polyomavirus-specific T cell immune responses in kidney transplant recipients diagnosed with BK Polyomavirus-associated nephropathy [PDF]

BMC Infectious Diseases, 2019
Background Adjustment of immunosuppression is the main therapy for BK polyomavirus (BKPyV)-associated nephropathy (BKPyVAN) after kidney transplantation (KT). Studies of BKPyV-specific T cell immune response are scarce.
Jackrapong Bruminhent, Supranart Srisala, Chompunut Klinmalai, Subencha Pinsai, Siriorn P. Watcharananan, Surasak Kantachuvesiri, Suradej Hongeng, Nopporn Apiwattanakul   +7 more
doaj   +5 more sources

Urine Donor–Derived Cell-Free DNA Helps Discriminate BK Polyomavirus-Associated Nephropathy in Kidney Transplant Recipients With BK Polyomavirus Infection [PDF]

Frontiers in Immunology, 2020
Background: Studies have shown that plasma donor–derived cell-free DNA (dd-cfDNA) can predict renal allograft antibody-mediated rejection. This study was performed to evaluate the value of urine dd-cfDNA concentration and dd-cfDNA fraction (%) for ...
Gang Huang, Changxi Wang, Shi-Cong Yang   +2 more
exaly   +4 more sources

Clinical Efficacy of Intravenous Immunoglobulin for BK Polyomavirus-Associated Nephropathy After Living Kidney Transplantation [PDF]

Therapeutics and Clinical Risk Management, 2020
Soichi Matsumura,1 Taigo Kato,1,2 Ayumu Taniguchi,1 Masataka Kawamura,1 Shigeaki Nakazawa,1 Tomoko Namba-Hamano,3 Toyofumi Abe,1 Norio Nonomura,1 Ryoichi Imamura1 1Department of Urology, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan;
Matsumura S, Kato T, Taniguchi A, Kawamura M, Nakazawa S, Namba-Hamano T, Abe T, Nonomura N, Imamura R   +8 more
doaj   +5 more sources

BK Polyomavirus-Associated Nephropathy and Hemorrhagic Cystitis in Transplant Recipients—What We Understand and What Remains Unclear [PDF]

Viruses
The reactivation of BK polyomavirus (BKPyV) during severe immunosuppression plays a crucial role in two significant syndromes observed in transplant recipients: BK polyomavirus-associated nephropathy (BKPyVAN) in kidney transplant patients and BK ...
Tang-Her Jaing, Yi-Lun Wang, Tsung-Yen Chang   +2 more
doaj   +4 more sources

BK polyomavirus-associated nephropathy [PDF]

Childhood Kidney Diseases, 2022
BK polyomavirus (BKPyV) is a ubiquitous virus residing in the kidney tubules and is clinically significant only in immunocompromised patients. In clinical practice, BKPyV is a causative pathogen of BKPyV-associated nephropathy (BKVAN) in kidney allograft
Yo Han Ahn, Hee Gyung Kang
doaj   +2 more sources