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High Incidence and Early Onset of Urinary Tract Cancers in Patients with BK Polyomavirus Associated Nephropathy [PDF]

open access: yesViruses, 2021
Over-immunosuppressed kidney transplant recipients are susceptible to malignancies and BK polyomavirus (BKPyV)-associated nephropathy (BKPyVAN). This study aimed to verify the association between BKPyV infection and urinary tract cancers (UTC).
Hsiang-Hao Hsu   +2 more
exaly   +7 more sources

Exploring the mechanism of BK polyomavirus-associated nephropathy through consensus gene network approach. [PDF]

open access: yesPLoS ONE, 2023
BK polyomavirus-associated nephropathy occurs in kidney transplant recipients under immunosuppressive treatment. BK polyomavirus is implicated in cancer development and invasion, and case reports of renal cell carcinoma and urothelial carcinoma possibly ...
Noriaki Sato   +8 more
doaj   +4 more sources

Development of BK polyomavirus-associated nephropathy risk prediction in kidney transplant recipients [PDF]

open access: yesRenal Failure
Background With the development of potential prevention therapies for BK polyomavirus (BKPyV)-associated nephropathy (BKPyVAN), risk prediction models are needed to identify kidney transplant recipients at high risk for BKPyVAN.Methods This single-center
Junji Yamauchi   +10 more
doaj   +4 more sources

Clinical Efficacy of Intravenous Immunoglobulin for BK Polyomavirus-Associated Nephropathy After Living Kidney Transplantation [PDF]

open access: yesTherapeutics and Clinical Risk Management, 2020
Soichi Matsumura,1 Taigo Kato,1,2 Ayumu Taniguchi,1 Masataka Kawamura,1 Shigeaki Nakazawa,1 Tomoko Namba-Hamano,3 Toyofumi Abe,1 Norio Nonomura,1 Ryoichi Imamura1 1Department of Urology, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan;
Matsumura S   +8 more
doaj   +5 more sources

BK Polyomavirus-specific T cell immune responses in kidney transplant recipients diagnosed with BK Polyomavirus-associated nephropathy [PDF]

open access: yesBMC Infectious Diseases, 2019
Background Adjustment of immunosuppression is the main therapy for BK polyomavirus (BKPyV)-associated nephropathy (BKPyVAN) after kidney transplantation (KT). Studies of BKPyV-specific T cell immune response are scarce.
Jackrapong Bruminhent   +7 more
doaj   +5 more sources

BK Polyomavirus-Associated Nephropathy and Hemorrhagic Cystitis in Transplant Recipients—What We Understand and What Remains Unclear [PDF]

open access: yesViruses
The reactivation of BK polyomavirus (BKPyV) during severe immunosuppression plays a crucial role in two significant syndromes observed in transplant recipients: BK polyomavirus-associated nephropathy (BKPyVAN) in kidney transplant patients and BK ...
Tang-Her Jaing   +2 more
doaj   +4 more sources

Native BK Polyomavirus Nephropathy in an Orthotopic Heart Transplant Patient

open access: yesJournal of Investigative Medicine High Impact Case Reports, 2023
BK polyomavirus nephropathy (BKVN) is a common cause of nephropathy in kidney transplant patients and is typically seen within the first year after transplantation.
Zachary M Thompson   +2 more
exaly   +2 more sources

Case Report: Late-onset BK polyomavirus-associated nephropathy in kidney transplant recipients: two cases and insights into underlying mechanisms [PDF]

open access: yesFrontiers in Medicine
BK polyomavirus–associated nephropathy (BKPyVAN) results from primary infection or reactivation of BK polyomavirus (BKPyV) and remains a significant complication in kidney transplant recipients, contributing to allograft dysfunction and premature ...
Tanja Belčič Mikič   +5 more
doaj   +2 more sources

Urine Donor–Derived Cell-Free DNA Helps Discriminate BK Polyomavirus-Associated Nephropathy in Kidney Transplant Recipients With BK Polyomavirus Infection [PDF]

open access: yesFrontiers in Immunology, 2020
Background: Studies have shown that plasma donor–derived cell-free DNA (dd-cfDNA) can predict renal allograft antibody-mediated rejection. This study was performed to evaluate the value of urine dd-cfDNA concentration and dd-cfDNA fraction (%) for ...
Xu-Tao Chen   +28 more
doaj   +2 more sources

Incidence of BK Virus in HIV-positive Kidney Transplant Recipients: Case Series From South Africa [PDF]

open access: yesTransplantation Direct
Background. BK virus-associated nephropathy (BKVN) is a viral complication after kidney transplantation and an important cause of graft dysfunction and loss.
Laurie Bertels, MBChB, FCS(SA)   +4 more
doaj   +2 more sources

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