Results 41 to 50 of about 2,798 (150)

Molecular Networks Involved in the Immune Control of BK Polyomavirus

Clinical and Developmental Immunology, 2012
BK polyomavirus infection is the important cause of virus-related nephropathy following kidney transplantation. BK virus reactivates in 30%–80% of kidney transplant recipients resulting in BK virus-related nephropathy in 1%–10% of cases.
Eva Girmanova, Irena Brabcova, Jiri Klema, Petra Hribova, Mariana Wohlfartova, Jelena Skibova, Ondrej Viklicky   +6 more
doaj   +1 more source

Simultaneous pancreas/kidney transplant recipients present with late-onset BK polyomavirus-associated nephropathy [PDF]

Nephrology Dialysis Transplantation, 2016
Infections have increased in simultaneous pancreas/kidney transplant recipients (SPKTRs) with BK polyomavirus (BKV)-associated nephropathy (BKVN) being the most important infectious cause of allograft loss. Comparisons of BKVN with kidney transplant recipients (KTRs), however, are lacking.We studied all SPKTRs and KTRs at our transplant centre between ...
Thomas, Schachtner, Marina, Zaks, Andreas, Kahl, Petra, Reinke   +3 more
openaire   +2 more sources

Complications post renal transplantation: literature focus on BK virus nephropathy and diagnostic tools actually available

Virology Journal, 2008
Clinical diagnosis of kidney transplants related illnesses is not a simple task. Several studies were conducted to define diseases and complications after renal transplantation, but there are no comprehensive guidelines about diagnostic tools for their ...
Miglio Umberto, Boldorini Renzo, Fioriti Daniela, Anzivino Elena, Bellizzi Anna, Mischitelli Monica, Chiarini Fernanda, Di Monaco Franco, Pietropaolo Valeria   +8 more
doaj   +1 more source

Cross‐Neutralizing and Broadly Neutralizing Human Antibodies Against Nonenveloped Viruses

European Journal of Immunology, Volume 56, Issue 10, October 2026.
In this review article, Marchand et al. compare cross ‐ and broadly ‐neutralizing human antibodies against non ‐ enveloped viruses from several major families, discussing their structural characteristics, neutralization mechanisms and relevance for the development of antiviral vaccines and therapeutics.
Sarah Marchand, Samy Taouli, Dorian McIlroy   +2 more
wiley   +1 more source

BK Polyomavirus in Renal Transplantation: Virological Notes for Monitoring and Diagnosis

Biomolecules
Polyomavirus-associated nephropathy was first reported over 50 years ago. However, it still represents a cause of renal injury in kidney transplant recipients, particularly in the first two years post-transplantation, with occurrence rates of 1–10%.
Cristina Costa, Francesca Sidoti, Alessandro Bondi, Antonio Curtoni   +3 more
doaj   +1 more source

A highly potent human antibody neutralizing all serotypes of BK polyomavirus.

PLoS Pathogens
BK polyomavirus infection poses a significant risk to kidney transplant recipients. Reactivation of dormant virus in the transplanted kidney, triggered by immunosuppression, can lead to BK polyomavirus-associated nephropathy in up to 10% of transplants ...
Marcel Weber, Simone Schmitt, Barbara Eicher, Jemima Seidenberg, Justina Rutkauskaite, Benedikt Stöckli, Catherine Townsend, Uyen Huynh-Do, Thomas Schachtner, Serena Delbue, Armin Mäder, Christoph Esslinger, Matthias Hillenbrand   +12 more
doaj   +1 more source

Evaluation of polyomavirus BK reactivation in lupus patients who underwent kidney transplantation

Microbiologia Medica, 2012
Background. A pathogenic role for polyomavirus BK in systemic lupus erythematosus (SLE) has been proposed, however no study evaluated the occurrence of BK replication in renal transplant recipients according to the underlying disease leading to ...
Cristina Costa, Giovanni Antonio Touscoz, Francesca Sidoti, Franca Sinesi, Daniela Re, Cinzia Balloco, Elsa Piasentin Alessio, Maria Messina, Giuseppe Paolo Segoloni, Rossana Cavallo   +9 more
doaj   +1 more source

From Data to Decisions: How Machine Learning and Generative Artificial Intelligence Are Redefining Precision Medicine in Kidney Transplantation

Organ Medicine, Volume 3, Issue 2, Page 102-118, June 2026.
This review evaluates how machine learning, multimodal integration, and generative AI optimize kidney transplant outcomes. These tools enable superior prediction and personalized therapy but face hurdles in data volume, generalizability, and ethics. Future clinical adoption depends on continued innovation and multidisciplinary collaboration to overcome
Maoxin Liao, Cheng Yang
wiley   +1 more source

Development of a droplet digital PCR assay for the detection of BK polyomavirus

Microbiology Spectrum
The objective of this study was to establish a more sensitive and specific diagnostic method for detecting plasma BK polyomavirus (BKPyV) DNA load in patients after renal transplantation using droplet digital polymerase chain reaction (ddPCR) and to ...
Lu Ai, Yating Zhao, Chianru Tan, Lu Bai, Gang Huang, Ruizhi Wang, Hao Huang, Xuegao Yu, Yong Guo, Peisong Chen   +9 more
doaj   +1 more source

BKTyper: Free Online Tool for Polyoma BK Virus VP1 and NCCR Typing

Viruses, 2020
Human BK polyomavirus (BKPyV) prevalence has been increasing due to the introduction of more potent immunosuppressive agents in transplant recipients, and its clinical interest. BKPyV has been linked mostly to polyomavirus-associated hemorrhagic cystitis,
Joan Martí-Carreras, Olga Mineeva-Sangwo, Dimitrios Topalis, Robert Snoeck, Graciela Andrei, Piet Maes   +5 more
doaj   +1 more source