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Frontiers in Immunology, 2015 In renal transplantation, BK-virus-associated nephropathy has emerged as a major complication, with a prevalence of 5–10% and graft loss in >50% of cases. BK-virus is a member of the Polyomavirus family and rarely induces apparent clinical disease in the
manon edekeyser +3 more
doaj +1 more source
The prevalence of the most important viral infections in renal transplant recipients in Serbia [PDF]
, 2012 Viruses are the main cause of opportunistic infections after kidney transplantation. The aim of this study was to determine the prevalence of cytomegalovirus (CMV), Epstein-Barr virus (EBV), B. K. virus (BKV) and John Cunningham virus (JCV) infections
Banko Ana +7 more
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Comparison of Immunohistochemical Staining for Large T Antigen and Capsid Protein VP1 in BK Polyomavirus-Associated Nephropathy [PDF]
Nephron, 2020 Aim: Most transplant centres use SV40 large T antigen (TAg) staining for the diagnosis and assessment of BK polyomavirus-associated nephropathy (BKPyVAN). This study was performed to evaluate the significance of capsid protein VP1 expression in BKPyVAN. Methods: We performed immunohistochemical staining using anti-SV40 TAg and anti-BKPyV VP1 antibodies
Kosuke Masutani +9 more
openaire +2 more sources
Transplantation, 2019 Background. With current immunosuppressive regimens, BK polyomavirus-associated nephropathy (BKPyVAN) is still a matter of concern. Stratification of patients at risk for allograft loss is of uttermost importance to guide treatment choice and assess prognosis.
Bouatou, Yassine +7 more
openaire +5 more sources
Surveillance of polyomavirus BK in relation to immunosuppressive therapy in kidney transplantation
Microbiologia Medica, 2012 Introduction. Reactivation of polyomavirus BK in kidney transplant recipients has been associated to the development of nephropathy (polyomavirus-associated nephropathy, PVAN), possibly leading to the loss of the transplanted organ.
Cristina Costa +8 more
doaj +1 more source
Kaohsiung Journal of Medical Sciences, 2016 Previous studies regarding the prevention of BK viremia following renal transplantation with fluoroquinolone have yielded conflicting results. The purpose of this systematic review was to examine the evidence regarding the efficacy of fluoroquinolone in ...
Tu-Run Song +6 more
doaj +1 more source
Molecular Networks Involved in the Immune Control of BK Polyomavirus
Clinical and Developmental Immunology, 2012 BK polyomavirus infection is the important cause of virus-related nephropathy following kidney transplantation. BK virus reactivates in 30%–80% of kidney transplant recipients resulting in BK virus-related nephropathy in 1%–10% of cases.
Eva Girmanova +6 more
doaj +1 more source
Simultaneous pancreas/kidney transplant recipients present with late-onset BK polyomavirus-associated nephropathy [PDF]
Nephrology Dialysis Transplantation, 2016 Infections have increased in simultaneous pancreas/kidney transplant recipients (SPKTRs) with BK polyomavirus (BKV)-associated nephropathy (BKVN) being the most important infectious cause of allograft loss. Comparisons of BKVN with kidney transplant recipients (KTRs), however, are lacking.We studied all SPKTRs and KTRs at our transplant centre between ...
Thomas, Schachtner +3 more
openaire +2 more sources
Possible antiviral effect of ciprofloxacin treatment on polyomavirus BK replication and analysis of non-coding control region sequences [PDF]
, 2013 Acute renal dysfunction (ARD) is a common complication in renal transplant recipients. Multiple factors contribute to ARD development, including acute rejection and microbial infections.
Anna Bellizzi +8 more
core +1 more source
Virology Journal, 2008 Clinical diagnosis of kidney transplants related illnesses is not a simple task. Several studies were conducted to define diseases and complications after renal transplantation, but there are no comprehensive guidelines about diagnostic tools for their ...
Miglio Umberto +8 more
doaj +1 more source