Results 21 to 30 of about 2,684 (148)

First confirmed case of native Polyomavirus BK nephropathy in a liver transplant recipient seven years post-transplant

Annals of Hepatology, 2015
Renal dysfunction frequently occurs in liver transplant recipients and is associated with increased morbidity and mortality. BK virus is a human polyoma virus that reactivates during immunocompromised states and is a known cause of renal allograft ...
Trana Hussaini
exaly   +3 more sources

Non-invasive urinary sediment double-immunostaining predicts BK polyomavirus associated-nephropathy in kidney transplant recipients. [PDF]

Ann Transl Med, 2020
The positive predictive value (PPV) of urinary decoy cells for diagnosing BK polyomavirus associated-nephropathy (BKPyVAN) is low. This study was designed to increase the PPV of urinary decoy cells for diagnosing BKPyVAN in kidney transplant recipients.A total of 105 urine sediment samples from 105 patients with positive BK viruria and decoy cells were
Chen XT, Chen WF, Hou XT, Yang SC, Yang HF, Li J, Deng RH, Huang Y, Nuertai Y, Wang CX, Qiu J, Huang G.   +11 more
europepmc   +4 more sources

Cell-Free Mitochondrial DNA: An Upcoming Non-Invasive Tool for Diagnosis of BK Polyomavirus-Associated Nephropathy. [PDF]

Biomolecules
Mitochondria are essential organelles that possess their own DNA. Mitochondrial dysfunction has been revealed in many kidney diseases, including BK polyomavirus-associated nephropathy (BKPyVAN). In this study, we introduce an innovative approach for non-invasive monitoring of mitochondrial impairment through urinary donor-derived cell-free ...
Guo L, Luo S, Wang X, Zhang N, Cheng Y, Shen J, Chen J, Wang R.   +7 more
europepmc   +4 more sources

BK and JC polyomavirus co-infection resulting in polyomavirus nephropathy and progressive multifocal leukoencephalopathy at the same time, a case report [PDF]

Brazilian Journal of Infectious Diseases
John Cunningham Virus (JCV) and BK Virus (BKV) are the most extensively studied Human Polyomaviruses (HPyVs), primarily associated with Progressive Multifocal Leukoencephalopathy (PML) and BKV Nephropathy (BKVN), respectively.
Sébastien Briol, Laura Labriola, Arnaud Devresse, Benoit Kabamba, Valeria Onofrj, Leïla Belkhir   +5 more
doaj   +2 more sources

Low 25-Hydroxyvitamin D Post-Kidney Transplant Is Associated with Increased Risk of BK Polyomavirus-Associated Nephropathy. [PDF]

Microorganisms
BK viremia (BKPyV-DNAemia) and nephropathy (BKPyVAN) are significant causes of morbidity and mortality in kidney transplant recipients (KTRs). Vitamin D supports immune function, yet low 25-hydroxyvitamin D [25(OH)D] is common among KTRs. The association between serum 25(OH)D, measured 61 days to 2 years post-transplant, and subsequent incident BKPyV ...
Raj SA, Zhou AL, Fedorova E, Yuan Z, Mandelbrot DA, Astor BC, Parajuli S.   +6 more
europepmc   +4 more sources

Incidence of BK Virus in HIV-positive Kidney Transplant Recipients: Case Series From South Africa [PDF]

Transplantation Direct
Background. BK virus-associated nephropathy (BKVN) is a viral complication after kidney transplantation and an important cause of graft dysfunction and loss.
Laurie Bertels, MBChB, FCS(SA), Kathryn Manning, MSc (Med), MPH, Andrew D. Redd, PhD, Zunaid Barday, MBChB, FCP(SA), Elmi Muller, MBChB, FCS(SA), PHD, MBA   +4 more
doaj   +2 more sources

Single-cell profiling reveals epithelial and immune responses in BK polyomavirus–infected human kidney biopsies [PDF]

JCI Insight
INTRODUCTION BK polyomavirus (BKV) infection is associated with injury and subsequent graft loss due to the extent of injury or rejection. However, the molecular mechanisms driving injury and subsequent adverse outcomes remain poorly understood.METHODS ...
Tess Marvin, Rachel Sealfon, Phillip J. McCown, Fadhl AlAkwaa, Evan A. Farkash, Edgar A. Otto, Felix Eichinger, Paul G. Cantalupo, Ping An, Rajasree Menon, Celine C. Berthier, Tavis J. Reed, Paula Arrowsmith, Lalita Subramanian, Kelly J. Shaffer, Silas P. Norman, Ramnika Gumber, Michael J. Imperiale, James M. Pipas, Olga G. Troyanskaya, Matthias Kretzler, Chandra L. Theesfeld, Abhijit S. Naik   +22 more
doaj   +2 more sources

Urothelial Carcinoma of the Bladder Following BK Virus Infection in a Pediatric Kidney Transplant Recipient. [PDF]

Pediatr Transplant
ABSTRACT Background Urothelial bladder carcinoma is extremely rare in children and its association with BK virus infection remains unclear. Methods We describe the case of an 11‐year‐old girl who developed a urothelial carcinoma of the bladder four years after receiving her first kidney transplant.
Ichas M, Allard L, Harper L, Yacoub M, Madden I, Vérité C, Godron-Dubrasquet A, Harambat J.   +7 more
europepmc   +2 more sources

Native BK Polyomavirus Nephropathy in an Orthotopic Heart Transplant Patient

Journal of Investigative Medicine High Impact Case Reports, 2023
BK polyomavirus nephropathy (BKVN) is a common cause of nephropathy in kidney transplant patients and is typically seen within the first year after transplantation.
Zachary M. Thompson MD, George Ajene DO, Prathit A. Kulkarni MD, Nidhi Aggarwal MD, Savitri Fedson MD, Maulin K. Shah MD   +5 more
doaj   +1 more source

Histologic versus Molecular Diagnosis of BK Polyomavirus–Associated Nephropathy [PDF]

Clinical Journal of the American Society of Nephrology, 2006
Although discovered in 1970 the BK virus infections had no significant clinical impact until the emergence of BK virus-associated allograft nephropathy (BKPVAN). Escalating clinical challenges required better diagnostic tools and delineation of uniform criteria for diagnosis.
Cinthia B, Drachenberg, John C, Papadimitriou, Emilio, Ramos   +2 more
openaire   +2 more sources