Results 31 to 40 of about 2,798 (150)

First confirmed case of native Polyomavirus BK nephropathy in a liver transplant recipient seven years post-transplant

Annals of Hepatology, 2015
Renal dysfunction frequently occurs in liver transplant recipients and is associated with increased morbidity and mortality. BK virus is a human polyoma virus that reactivates during immunocompromised states and is a known cause of renal allograft ...
Yangmin Zeng, Alex Magil, Trana Hussaini, C. Kit Yeung, Siegfried R. Erb, Vladimir Marquez-Alazagara, Eric M. Yoshida, MD, MHSc, FRCP(C), FACP, FACG, FCAHS, FAASLD   +6 more
doaj   +1 more source

BK polyomavirus microRNA expression and sequence variation in polyomavirus-associated nephropathy

Journal of Clinical Virology, 2018
BK polyomavirus (BKPyV) infection is a common asymptomatic viral infection in the general population. Severe complications are seen in immunocompromised individuals, such as polyomavirus-associated nephropathy (PyVAN) in renal transplant recipients. Information on BKPyV microRNA expressions is scarce, although polyomavirus-encoded microRNAs have been ...
Virtanen, Elina, Seppälä, Hanna, Helanterä, Ilkka, Laine, Pia, Lautenschlager, Irmeli, Paulin, Lars, Mannonen, Laura, Auvinen, Petri, Auvinen, Eeva   +8 more
openaire   +3 more sources

Polyomavirus specific cellular immunity: from BK-virus-specific cellular immunity to BK-virus-associated nephropathy ?

Frontiers in Immunology, 2015
In renal transplantation, BK-virus-associated nephropathy has emerged as a major complication, with a prevalence of 5–10% and graft loss in >50% of cases. BK-virus is a member of the Polyomavirus family and rarely induces apparent clinical disease in the
manon edekeyser, helene efrancois, severine ebeaudreuil, Antoine eDurrbach   +3 more
doaj   +1 more source

Cell-Free Mitochondrial DNA: An Upcoming Non-Invasive Tool for Diagnosis of BK Polyomavirus-Associated Nephropathy. [PDF]

Biomolecules
Mitochondria are essential organelles that possess their own DNA. Mitochondrial dysfunction has been revealed in many kidney diseases, including BK polyomavirus-associated nephropathy (BKPyVAN). In this study, we introduce an innovative approach for non-invasive monitoring of mitochondrial impairment through urinary donor-derived cell-free ...
Guo L, Luo S, Wang X, Zhang N, Cheng Y, Shen J, Chen J, Wang R.   +7 more
europepmc   +4 more sources

Comparison of Immunohistochemical Staining for Large T Antigen and Capsid Protein VP1 in BK Polyomavirus-Associated Nephropathy [PDF]

Nephron, 2020
Aim: Most transplant centres use SV40 large T antigen (TAg) staining for the diagnosis and assessment of BK polyomavirus-associated nephropathy (BKPyVAN). This study was performed to evaluate the significance of capsid protein VP1 expression in BKPyVAN. Methods: We performed immunohistochemical staining using anti-SV40 TAg and anti-BKPyV VP1 antibodies
Kosuke Masutani, Yuta Matsukuma, Akihiro Tsuchimoto, Yasuhiro Okabe, Atsushi Doi, Keizo Kaku, Masafumi Nakamura, Toshiaki Nakano, Kazuhiko Tsuruya, Takanari Kitazono   +9 more
openaire   +2 more sources

Low 25-Hydroxyvitamin D Post-Kidney Transplant Is Associated with Increased Risk of BK Polyomavirus-Associated Nephropathy. [PDF]

Microorganisms
BK viremia (BKPyV-DNAemia) and nephropathy (BKPyVAN) are significant causes of morbidity and mortality in kidney transplant recipients (KTRs). Vitamin D supports immune function, yet low 25-hydroxyvitamin D [25(OH)D] is common among KTRs. The association between serum 25(OH)D, measured 61 days to 2 years post-transplant, and subsequent incident BKPyV ...
Raj SA, Zhou AL, Fedorova E, Yuan Z, Mandelbrot DA, Astor BC, Parajuli S.   +6 more
europepmc   +4 more sources

Belatacept and the Risk of Cytomegalovirus, BK Polyomavirus, and Epstein-Barr Virus Post-transplant Lymphoproliferative Disease After Kidney Transplantation: A Meta-Analysis and Systematic Review. [PDF]

J Transplant
Background The long‐term risk of cytomegalovirus (CMV), Epstein–Barr virus (EBV)‐associated post‐transplant lymphoproliferative disorder (PTLD), and BK viral infections from belatacept is unclear. This review aimed to evaluate these outcomes. Methods Several databases were reviewed from inception through September 2025 using the keywords “belatacept ...
Abad CLR, Razonable RR.
europepmc   +2 more sources

Surveillance of polyomavirus BK in relation to immunosuppressive therapy in kidney transplantation

Microbiologia Medica, 2012
Introduction. Reactivation of polyomavirus BK in kidney transplant recipients has been associated to the development of nephropathy (polyomavirus-associated nephropathy, PVAN), possibly leading to the loss of the transplanted organ.
Cristina Costa, Francesca Sidoti, Cinzia Balloco, Salvatore Simeone, Elsa Piasentin Alessio, Giovanni Antonio Touscoz, Maria Messina, Giuseppe Paolo Segoloni, Rossana Cavallo   +8 more
doaj   +1 more source

A Multicenter Application of the 2018 Banff Classification for BK Polyomavirus-associated Nephropathy in Renal Transplantation

Transplantation, 2019
Background. With current immunosuppressive regimens, BK polyomavirus-associated nephropathy (BKPyVAN) is still a matter of concern. Stratification of patients at risk for allograft loss is of uttermost importance to guide treatment choice and assess prognosis.
Bouatou, Yassine, Nguyen, Tri Q., Roelofs, Joris J. T. H., Bemelman, Frederike J., Michielsen, Laura, Goldschmeding, Roel, Kers, Jesper, Florquin, Sandrine   +7 more
openaire   +4 more sources

Fluoroquinolone prophylaxis in preventing BK polyomavirus infection after renal transplant: A systematic review and meta-analysis

Kaohsiung Journal of Medical Sciences, 2016
Previous studies regarding the prevention of BK viremia following renal transplantation with fluoroquinolone have yielded conflicting results. The purpose of this systematic review was to examine the evidence regarding the efficacy of fluoroquinolone in ...
Tu-Run Song, Zheng-Sheng Rao, Yang Qiu, Jin-Peng Liu, Zhong-Li Huang, Xian-Ding Wang, Tao Lin   +6 more
doaj   +1 more source