Results 31 to 40 of about 2,684 (148)

Conversion from mycophenolate mofetil to mizoribine in the early stages of BK polyomavirus infection could improve kidney allograft prognosis: a single-center study from China

BMC Nephrology, 2021
Background Some studies have suggested mizoribine (MZR) could inhibit the replication of BK polyomavirus (BKPyV). The purpose of this study was to explore whether conversion from mycophenolate mofetil (MMF) to MZR in the early stages of BKPyV infection ...
Ping Li, Dongrui Cheng, Jiqiu Wen, Xuefeng Ni, Kenan Xie, Xue Li, Jinsong Chen   +6 more
doaj   +1 more source

BK virus nephropathy in a heart transplant recipient

Brazilian Journal of Nephrology, 2021
BK virus nephropathy in kidney transplantation is widely recognized as an important cause of graft dysfunction and loss. In the case of transplants of organs other than kidney, BK virus nephropathy in native kidneys has been recognized as a cause of ...
John Fredy Nieto-Ríos, Diego Armando Benavides-Henao, Arbey Aristizabal-Alzate, Carol Morales-Contreras, Diana Carolina Chacón-Jaimes, Gustavo Zuluaga-Valencia, Lina María Serna-Higuita   +6 more
doaj   +2 more sources

BK polyomavirus nephropathy in two kidney transplant patients with distinct diagnostic strategies for BK virus and similar clinical outcomes: two case reports

Journal of Medical Case Reports, 2017
Background BK polyomavirus-associated nephropathy is an important cause of post-transplantation renal failure. We present two cases of BK polyomavirus-associated nephropathy who were submitted to contrasting strategies of clinical follow-up to BK ...
Ana Luisa Figueira Gouvêa, Rachel Ingrid Juliboni Cosendey, Ana Lucia Rosa Nascimento, Fabiana Rabe Carvalho, Andrea Alice Silva, Heleno Pinto de Moraes, Mayra Carrijo Rochael, Rafael Brandão Varella, Stephanie Gomes Almeida, Jorge Reis Almeida, Jocemir Ronaldo Lugon   +10 more
doaj   +1 more source

Persistently high-level polyomavirus BK replication in the absence of renal function abnormalities in a kidney transplant recipient

Microbiologia Medica, 2016
Polyomavirus-associated nephropathy is an important cause of allograft dysfunction and graft loss after kidney transplantation. Even if histological evaluation is the gold standard for graft study and diagnosis of polyomavirus-associated nephropathy, K ...
Antonio Curtoni, Cristina Costa, Maria Messina, Francesca Sidoti, Andrea Piceghello, Gabriele Bianco, Luigi Biancone, Giuseppe Paolo Segoloni, Rossana Cavallo   +8 more
doaj   +1 more source

Role of BK Virus CTLs in the Treatment of BK Virus-Associated Nephropathy in Kidney-Transplant and Hematopoietic Cell Transplant Recipients. [PDF]

Transpl Infect Dis
Third‐party, BK virus‐specific cytotoxic T lymphocytes (CTLs) were safe and effective in reducing viremia in kidney and stem cell transplant recipients with BK virus nephropathy. However, they did not improve kidney function. Earlier administration may be more beneficial before nephropathy and irreversible damage occur.
Olson A, Li YE, Basar R, Banerjee P, Kaur I, Abueg G, Sylejmani M, Uprety N, Shrestha R, Silva FR, Page V, Champlin RE, Kontoyiannis DP, Chemaly RF, Shpall EJ, Moore L, Gaber OA, Rezvani K, Abudayyeh A.   +18 more
europepmc   +2 more sources

BK polyomavirus microRNA expression and sequence variation in polyomavirus-associated nephropathy

Journal of Clinical Virology, 2018
BK polyomavirus (BKPyV) infection is a common asymptomatic viral infection in the general population. Severe complications are seen in immunocompromised individuals, such as polyomavirus-associated nephropathy (PyVAN) in renal transplant recipients. Information on BKPyV microRNA expressions is scarce, although polyomavirus-encoded microRNAs have been ...
Virtanen, Elina, Seppälä, Hanna, Helanterä, Ilkka, Laine, Pia, Lautenschlager, Irmeli, Paulin, Lars, Mannonen, Laura, Auvinen, Petri, Auvinen, Eeva   +8 more
openaire   +3 more sources

Polyomavirus specific cellular immunity: from BK-virus-specific cellular immunity to BK-virus-associated nephropathy ?

Frontiers in Immunology, 2015
In renal transplantation, BK-virus-associated nephropathy has emerged as a major complication, with a prevalence of 5–10% and graft loss in >50% of cases. BK-virus is a member of the Polyomavirus family and rarely induces apparent clinical disease in the
manon edekeyser, helene efrancois, severine ebeaudreuil, Antoine eDurrbach   +3 more
doaj   +1 more source

A Multicenter Application of the 2018 Banff Classification for BK Polyomavirus-associated Nephropathy in Renal Transplantation

Transplantation, 2019
Background. With current immunosuppressive regimens, BK polyomavirus-associated nephropathy (BKPyVAN) is still a matter of concern. Stratification of patients at risk for allograft loss is of uttermost importance to guide treatment choice and assess prognosis.
Bouatou, Yassine, Nguyen, Tri Q., Roelofs, Joris J. T. H., Bemelman, Frederike J., Michielsen, Laura, Goldschmeding, Roel, Kers, Jesper, Florquin, Sandrine   +7 more
openaire   +4 more sources

Comparison of Immunohistochemical Staining for Large T Antigen and Capsid Protein VP1 in BK Polyomavirus-Associated Nephropathy [PDF]

Nephron, 2020
Aim: Most transplant centres use SV40 large T antigen (TAg) staining for the diagnosis and assessment of BK polyomavirus-associated nephropathy (BKPyVAN). This study was performed to evaluate the significance of capsid protein VP1 expression in BKPyVAN. Methods: We performed immunohistochemical staining using anti-SV40 TAg and anti-BKPyV VP1 antibodies
Kosuke Masutani, Yuta Matsukuma, Akihiro Tsuchimoto, Yasuhiro Okabe, Atsushi Doi, Keizo Kaku, Masafumi Nakamura, Toshiaki Nakano, Kazuhiko Tsuruya, Takanari Kitazono   +9 more
openaire   +2 more sources

Surveillance of polyomavirus BK in relation to immunosuppressive therapy in kidney transplantation

Microbiologia Medica, 2012
Introduction. Reactivation of polyomavirus BK in kidney transplant recipients has been associated to the development of nephropathy (polyomavirus-associated nephropathy, PVAN), possibly leading to the loss of the transplanted organ.
Cristina Costa, Francesca Sidoti, Cinzia Balloco, Salvatore Simeone, Elsa Piasentin Alessio, Giovanni Antonio Touscoz, Maria Messina, Giuseppe Paolo Segoloni, Rossana Cavallo   +8 more
doaj   +1 more source