Results 31 to 40 of about 3,946 (192)

Role of BK Virus CTLs in the Treatment of BK Virus-Associated Nephropathy in Kidney-Transplant and Hematopoietic Cell Transplant Recipients. [PDF]

Transpl Infect Dis
Third‐party, BK virus‐specific cytotoxic T lymphocytes (CTLs) were safe and effective in reducing viremia in kidney and stem cell transplant recipients with BK virus nephropathy. However, they did not improve kidney function. Earlier administration may be more beneficial before nephropathy and irreversible damage occur.
Olson A, Li YE, Basar R, Banerjee P, Kaur I, Abueg G, Sylejmani M, Uprety N, Shrestha R, Silva FR, Page V, Champlin RE, Kontoyiannis DP, Chemaly RF, Shpall EJ, Moore L, Gaber OA, Rezvani K, Abudayyeh A.   +18 more
europepmc   +2 more sources

BK polyomavirus nephropathy in two kidney transplant patients with distinct diagnostic strategies for BK virus and similar clinical outcomes: two case reports

Journal of Medical Case Reports, 2017
Background BK polyomavirus-associated nephropathy is an important cause of post-transplantation renal failure. We present two cases of BK polyomavirus-associated nephropathy who were submitted to contrasting strategies of clinical follow-up to BK ...
Ana Luisa Figueira Gouvêa, Rachel Ingrid Juliboni Cosendey, Ana Lucia Rosa Nascimento, Fabiana Rabe Carvalho, Andrea Alice Silva, Heleno Pinto de Moraes, Mayra Carrijo Rochael, Rafael Brandão Varella, Stephanie Gomes Almeida, Jorge Reis Almeida, Jocemir Ronaldo Lugon   +10 more
doaj   +1 more source

Different behaviour of BK-virus infection in liver transplant recipients [PDF]

, 2016
Polyomavirus BK (BKV) infects up to 90% of the general population. After primary infection, occurring early during childhood, a state of non-replicative infection is established in the reno-urinary tract, without complications for immunocompetent hosts ...
MITTERHOFER, Anna Paola, Muiesan, Paolo, TINTI, FRANCESCA, UMBRO, ILARIA   +3 more
core   +3 more sources

Complete genome sequence of BK polyomavirus subtype Ib-1 detected in a kidney transplant patient with BK viremia using shotgun sequencing [PDF]

, 2017
We report here the complete genome sequence of polyomavirus BK subtype Ib-1, isolate AR11, identified in urine from a human kidney transplant recipient with a clinical diagnosis of BK viremia. The AR11 isolate is closely related to reference strain human
Brennan, Daniel C, Finn, Patricia W, Perkins, David L, Rani, Asha, Ranjan, Ravi   +4 more
core   +2 more sources

Unraveling the Role of Allo-Antibodies and Transplant Injury. [PDF]

, 2016
Alloimmunity driving rejection in the context of solid organ transplantation can be grossly divided into mechanisms predominantly driven by either T cell-mediated rejection (TCMR) and antibody-mediated rejection (ABMR), though the co-existence of both ...
Matsuda, Yoshiko, Sarwal, Minnie M
core   +2 more sources

Persistently high-level polyomavirus BK replication in the absence of renal function abnormalities in a kidney transplant recipient

Microbiologia Medica, 2016
Polyomavirus-associated nephropathy is an important cause of allograft dysfunction and graft loss after kidney transplantation. Even if histological evaluation is the gold standard for graft study and diagnosis of polyomavirus-associated nephropathy, K ...
Antonio Curtoni, Cristina Costa, Maria Messina, Francesca Sidoti, Andrea Piceghello, Gabriele Bianco, Luigi Biancone, Giuseppe Paolo Segoloni, Rossana Cavallo   +8 more
doaj   +1 more source

Cell-Free Mitochondrial DNA: An Upcoming Non-Invasive Tool for Diagnosis of BK Polyomavirus-Associated Nephropathy. [PDF]

Biomolecules
Mitochondria are essential organelles that possess their own DNA. Mitochondrial dysfunction has been revealed in many kidney diseases, including BK polyomavirus-associated nephropathy (BKPyVAN). In this study, we introduce an innovative approach for non-invasive monitoring of mitochondrial impairment through urinary donor-derived cell-free ...
Guo L, Luo S, Wang X, Zhang N, Cheng Y, Shen J, Chen J, Wang R.   +7 more
europepmc   +4 more sources

First confirmed case of native Polyomavirus BK nephropathy in a liver transplant recipient seven years post-transplant

Annals of Hepatology, 2015
Renal dysfunction frequently occurs in liver transplant recipients and is associated with increased morbidity and mortality. BK virus is a human polyoma virus that reactivates during immunocompromised states and is a known cause of renal allograft ...
Yangmin Zeng, Alex Magil, Trana Hussaini, C. Kit Yeung, Siegfried R. Erb, Vladimir Marquez-Alazagara, Eric M. Yoshida, MD, MHSc, FRCP(C), FACP, FACG, FCAHS, FAASLD   +6 more
doaj   +1 more source

Low 25-Hydroxyvitamin D Post-Kidney Transplant Is Associated with Increased Risk of BK Polyomavirus-Associated Nephropathy. [PDF]

Microorganisms
BK viremia (BKPyV-DNAemia) and nephropathy (BKPyVAN) are significant causes of morbidity and mortality in kidney transplant recipients (KTRs). Vitamin D supports immune function, yet low 25-hydroxyvitamin D [25(OH)D] is common among KTRs. The association between serum 25(OH)D, measured 61 days to 2 years post-transplant, and subsequent incident BKPyV ...
Raj SA, Zhou AL, Fedorova E, Yuan Z, Mandelbrot DA, Astor BC, Parajuli S.   +6 more
europepmc   +4 more sources

Ureteral stent placement increases the risk for developing BK viremia after kidney transplantation. [PDF]

, 2014
The placement of ureteral stent (UrSt) at kidney transplantation reduces major urological complications but increases the risk for developing nephropathy from the BK virus.
Dharnidharka, Vikas R, Gregg, Jon A, Hashim, Faris, Rehman, Shehzad   +3 more
core   +4 more sources