Development of a droplet digital PCR assay for the detection of BK polyomavirus
Microbiology SpectrumThe objective of this study was to establish a more sensitive and specific diagnostic method for detecting plasma BK polyomavirus (BKPyV) DNA load in patients after renal transplantation using droplet digital polymerase chain reaction (ddPCR) and to ...
Lu Ai +9 more
doaj +1 more source
Risk factors for polyoma virus nephropathy [PDF]
, 2017 Background. Polyoma virus-associated nephropathy (PVN) is a common cause of renal transplant failure. The risk factors for the development of PVN have not yet been studied in large cohorts of patients for periods of 20 years. Methods.
Bubendorf, Lukas +5 more
core
BK Virus Nephropathy: Prevalence, Impact and Management Strategies
International Journal of Nephrology and Renovascular Disease, 2020 Rajeev Sharma,1,2 Mareena Zachariah3 1School of Medicine, University of Nevada Las Vegas, Las Vegas, NV, USA; 2Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA; 3Department of Nephrology, Wayne State University ...
Sharma R, Zachariah M
doaj
Polyomavirus BK Nephropathy-Associated Transcriptomic Signatures: A Critical Reevaluation
Transplantation Direct, 2018 Background. Recent work using DNA microarrays has suggested that genes related to DNA replication, RNA polymerase assembly, and pathogen recognition receptors can serve as surrogate tissue biomarkers for polyomavirus BK nephropathy (BKPyVN). Methods.
Ling Pan, MD +7 more
doaj +1 more source
BK virus infection, replication, and diseases in pediatric kidney transplantation [PDF]
, 2018 Polyomavirus-associated nephropathy is diagnosed in 2-8% of pediatric renal transplants and often precedes renal allograft dysfunction. Without intervention, however, significant graft dysfunction is observed in more than 50% of cases, although ...
Acott, Philip, Hirsch, Hans
core
Efficacy and Safety of Ciprofloxacin for Prophylaxis of Polyomavirus BK Virus–Associated Hemorrhagic Cystitis in Allogeneic Hematopoietic Stem Cell Transplantation Recipients [PDF]
, 2010 Polyoma virus BK–induced hemorrhagic cystitis is an important cause of morbidity after hematopoietic stem cell transplantation (HSCT). Fluoroquinolones have been shown in vitro to inhibit BK viral replication by direct inhibition of the BK-encoded DNA ...
Bowd, Kathryn +9 more
core +2 more sources
Clinical Case Reports, Volume 14, Issue 1, January 2026.ABSTRACT Kidney transplantation increases the survival rate of end‐stage renal disease patients; however, acute rejection and glomerulonephritis, such as the uncommon non‐lupus full‐house nephropathy (NLFHN), can lead to graft dysfunction. NLFHN exhibits a characteristic lupus immunofluorescence pattern in the absence of systemic lupus features, which ...
Tala Pourlak, Farahnoosh Farnood
wiley +1 more source
Renal Allograft Biopsies with Polyomavirus BK Nephropathy: Turin Transplant Center, 2015–19
Viruses, 2020 Background: In kidney transplant patients, polyomavirus-associated nephropathy (PVAN) represents a serious complication; the key factor for the development of PVAN is immunosuppression level and modulation of anti-rejection treatment represents the first
Elisa Zanotto +10 more
doaj +1 more source
Polyomavirus Bk Infection in Renal Transplant Recipients [PDF]
, 2005 peer reviewedBeside acute rejection or immunosuppressive therapy toxicity, infection by Polyomavirus BK, usually not aggressive in immunoactive patients, has emerged as an important factor affecting graft function in renal transplant recipients.
Bonvoisin, Catherine +1 more
core
Detection of Malawi polyomavirus sequences in secondary lymphoid tissues from Italian healthy children: a transient site of infection [PDF]
, 2016 BACKGROUND: The novel Malawi polyomavirus (MWPyV) was initially detected in stool specimens from healthy children and children with gastrointestinal symptoms, mostly diarrhea, indicating that MWPyV might play a role in human gastroenteric diseases ...
Comar, M +4 more
core +2 more sources