Results 81 to 90 of about 3,946 (192)

Long‐Term Outcomes of BK Viremia in Kidney Transplant Recipients

Clinical Transplantation, Volume 39, Issue 10, October 2025.
ABSTRACT Background BK viremia is associated with worse kidney transplant function and de novo donor‐specific antibodies (DSA), but mortality and graft survival are not impacted in the short‐ and intermediate‐term. The long‐term impact of BK viremia remains unclear.
Srijan Tandukar, Qufei Wu, Sneha Chandrashekar, Divyash Shah, Chienhui Chiang, Kathryn Couch, Jennifer Trofe, Elizabeth M. Sonnenberg, Peter Abt, Mary Ann Lim, Vishnu Potluri, Roy Bloom   +11 more
wiley   +1 more source

JC Polyomavirus-Associated Nephropathy Case Report: Clinical and Laboratory Learning

British Journal of Biomedical Science
IntroductionJohn Cunningham (JC) virus is commonly associated with progressive multifocal leukoencephalopathy. However, this polyomavirus can also be a rare etiological agent of nephropathy in renal transplant recipients.
Rachael M. Tomb, Siobhan K. McManus, David Kipgen, Sawsan Yaqub, Sally Taylor, Rory N. Gunson   +5 more
doaj   +1 more source

Identification of a novel human polyomavirus in organs of the gastrointestinal tract [PDF]

, 2013
Peer reviewedPublisher ...
Calvignac-Spencer, Sebastien, Ehlers, Bernhard, Hofmann, Jorg, Korup, Sarah, Moens, Ugo, Rietscher, Janita, Sauer, Igor, Schmuck, Rosa, Trusch, Franziska, Voigt, Sebastian   +9 more
core   +4 more sources

Similarities and Differences Between Allogeneic Hematopoietic Cell and Organ Transplantation and What We Can Learn From Each Other to Guide Global Health Strategy

Clinical Transplantation, Volume 39, Issue 10, October 2025.
ABSTRACT Background Allogeneic hematopoietic cell transplantation (HCT) and solid organ transplantation (SOT) have evolved into successful, curative treatments for many severe congenital and acquired diseases. Both use medical products of human origin and should therefore have overarching regulatory frameworks.
Hildegard T. Greinix, Arthur Matas, Mickey B. C. Koh, Lydia Foeken, Nina Worel, Amanda Vinson, Hassan Ibrahim, Deirdre Sawinski, Adriana Seber, Maryam Valapour, Yoshiko Atsuta, Thilo Mengling, John Lake, Thomas Wekerle, Daniel Weisdorf   +14 more
wiley   +1 more source

Regulation of Polyomavirus Transcription by Viral and Cellular Factors

Viruses, 2020
Polyomavirus infection is widespread in the human population. This family of viruses normally maintains latent infection within the host cell but can cause a range of human pathologies, especially in immunocompromised individuals.
June F. Yang, Jianxin You
doaj   +1 more source

Risk factors for BK viremia in kidney transplant recipients [PDF]

, 2015
Background. In the past 20 years, BK virus has emerged as a cause of early graft dysfunction after kidney transplantation. In the setting of chronic immunosuppression (IS), the latent virus can reactivate, leading to BK viremia (10-20%) and in 1-10% of ...
HABISREUTINGER, F.
core  

The DNA damage response promotes Polyomavirus JC infection by nucleus to cytoplasm NF-Kappa B activation. [PDF]

, 2017
Background: Infection of glial cells by human neurotropic polyomavirus JC (JCV), the causative agent of the CNS demyelinating disease progressive multifocal leukoencephalopathy (PML), rapidly inflicts damage to cellular DNA.
Bellizzi, Anna, Ibba, Gabriele, Palamara, Anna T., Pietropaolo, Valeria, White, Martyn K., Wollebo, Hassen, Wollebo|   +6 more
core   +1 more source

Manufacturing and clinical applications of non‐CAR‐T immune effector cells

Transfusion, EarlyView.
Thane Kubik, Theodros Mamo, David H. McKenna   +2 more
wiley   +1 more source

First‐In‐Human, Randomized, Placebo‐Controlled, SAD and MAD Trial to Evaluate Safety, Tolerability, and PK/PD Modeling of Potravitug in Healthy Adults

Clinical and Translational Science, Volume 18, Issue 8, August 2025.
ABSTRACT BK polyomavirus (BKPyV) affects 10%–30% of kidney‐transplant recipients receiving immunosuppressive therapy, potentially leading to nephropathy, graft dysfunction, graft loss, and increased mortality. Despite the medical need, no targeted therapies exist.
Marcus May, Julia K. Bialek‐Waldmann, Andrew Wright, Scott Gruver, Joshuaine Grant, Barbara Eicher, Jemima Seidenberg, Gerald P. Parzmair, Juergen Beck   +8 more
wiley   +1 more source

Prevalence of Polyomavirus BK and JC Infection and Replication in 400 Healthy Blood Donors [PDF]

, 2017
BackgroundThe replication of BK virus (BKV) and JC virus (JCV) is linked to polyomavirus-associated nephropathy, hemorrhagic cystitis, and multifocal leukoencephalopathy in immunodeficient patients, but the behavior of these viruses in immunocompetent ...
Buser, Andreas, Dumoulin, Alexis, Egli, Adrian, Gosert, Rainer, Hirsch, Hans H., Infanti, Laura, Samaridis, Jacqueline, Stebler, Christine   +7 more
core