Results 41 to 50 of about 10,884 (222)
Purpose: Hemorrhagic cystitis (HC) which occurs in 9%–31% of recipients after hematopoietic stem cell transplantation (HSCT) is an important cause of morbidity and mortality.
Ayça Koca Yozgat +7 more
doaj +1 more source
Detection and differentiation of human polyomaviruses JC and BK by LightCycler PCR [PDF]
Human polyomaviruses JC and BK may cause several clinical manifestations in immunocompromised hosts, including progressive multifocal leukoencephalopathy and hemorrhagic cystitis.
Whiley, David M. +2 more
core +1 more source
BK Virus in Cancer Development
Polyomavirus (PyV) was discovered by accident in 1950 in the course of describing an infectious factor causing multiple tumours in rodents. The term is derived from two Greek words: poly (many) and oma (tumour).
Pasternak Justyna +2 more
doaj +1 more source
Detection of Bk Polyomavirus Antigen in Patients with Acute Lymphoblastic Leukemia
Background: BK polyomavirus that is acquired in early childhood as BKPyV is near ubiquitous in adults with a seroprevalence of >80%, it has been found as the main cause of hemorrhagic cystitis in hematopoietic stem cell transplantation patients, due to
Safa H Ali , +3 more
doaj +1 more source
Human polyomaviruses in children undergoing transplantation, United States, 2008-2010 [PDF]
Immunocompromised patients are at risk for disease caused by infection by some polyomaviruses. To define the prevalence of polyomaviruses in children undergoing transplantation, we collected samples from a longitudinal cohort and tested for the 9 known ...
Bauer, Irma +11 more
core +2 more sources
Molecular Evaluation of BK Polyomavirus Nephropathy
Understanding at a molecular level, the immunologic response of polyomavirus nephropathy (PVN), a critical cause of kidney graft loss, could lead to new targets for treatment and diagnosis. We undertook a transcriptional evaluation of kidney allograft biopsies from recipients with PVN or acute rejection (AR), as well as from recipients with stable ...
R B, Mannon +9 more
openaire +2 more sources
BK Polyomavirus-Induced Nephropathy in Native Kidney
BK polyomavirus has been well-studied as an opportunistic infection in immunocompromised kidney transplant patients. In the majority of the population, BK polyomavirus establishes a lifelong infection in renal tubular and uroepithelial cells; however, in an immunocompromised state, the virus can reactivate and can lead to BK polyomavirus-associated ...
Munjal, Ripudaman S +3 more
openaire +2 more sources
Taking the Scenic Route: Polyomaviruses Utilize Multiple Pathways to Reach the Same Destination
Members of the Polyomaviridae family differ in their host range, pathogenesis, and disease severity. To date, some of the most studied polyomaviruses include human JC, BK, and Merkel cell polyomavirus and non-human subspecies murine and simian virus 40 ...
Colleen L. Mayberry, Melissa S. Maginnis
doaj +1 more source
Evaluation of polyomavirus BK reactivation in lupus patients who underwent kidney transplantation
Background. A pathogenic role for polyomavirus BK in systemic lupus erythematosus (SLE) has been proposed, however no study evaluated the occurrence of BK replication in renal transplant recipients according to the underlying disease leading to ...
Cristina Costa +9 more
doaj +1 more source
The DNA damage response promotes Polyomavirus JC infection by nucleus to cytoplasm NF-Kappa B activation. [PDF]
Background: Infection of glial cells by human neurotropic polyomavirus JC (JCV), the causative agent of the CNS demyelinating disease progressive multifocal leukoencephalopathy (PML), rapidly inflicts damage to cellular DNA.
Bellizzi, Anna +6 more
core +1 more source

