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The human polyomavirus BK: Potential role in cancer [PDF]
AbstractIn human cancer, a role has been suggested for the human polyomavirus BK, primarily associated with tubulointerstitial nephritis and ureteric stenosis in renal transplant recipients, and with hemorrhagic cystitis in bone marrow transplant (BMT) recipients.
FIORITI, DANIELA +6 more
openaire +6 more sources
Persistently high-level polyomavirus BK replication in the absence of renal function abnormalities in a kidney transplant recipient [PDF]
Polyomavirus-associated nephropathy is an important cause of allograft dysfunction and graft loss after kidney transplantation. Even if histological evaluation is the gold standard for graft study and diagnosis of polyomavirus-associated nephropathy, K ...
Antonio Curtoni +8 more
doaj +2 more sources
BK Polyomavirus-Associated Nephropathy and Hemorrhagic Cystitis in Transplant Recipients-What We Understand and What Remains Unclear. [PDF]
The reactivation of BK polyomavirus (BKPyV) during severe immunosuppression plays a crucial role in two significant syndromes observed in transplant recipients: BK polyomavirus-associated nephropathy (BKPyVAN) in kidney transplant patients and BK ...
Jaing TH, Wang YL, Chang TY.
europepmc +2 more sources
Development of a droplet digital PCR assay for the detection of BK polyomavirus. [PDF]
The objective of this study was to establish a more sensitive and specific diagnostic method for detecting plasma BK polyomavirus (BKPyV) DNA load in patients after renal transplantation using droplet digital polymerase chain reaction (ddPCR) and to ...
Ai L +9 more
europepmc +2 more sources
In renal transplantation, BK-virus-associated nephropathy has emerged as a major complication, with a prevalence of 5–10% and graft loss in >50% of cases. BK-virus is a member of the Polyomavirus family and rarely induces apparent clinical disease in the
manon edekeyser +3 more
doaj +2 more sources
BackgroundBK polyomavirus infection results in renal allograft dysfunction, and it is important to find methods of prediction and treatment. As a regulator of host immunity, changes in the gut microbiota are associated with a variety of infections ...
Jian Zhang +6 more
doaj +1 more source
Cytomegalovirus and polyomavirus BK posttransplant [PDF]
Virus replication and progression to disease in transplant patients is determined by patient-, graft- and virus-specific factors. This complex interaction is modulated by the net state of immunosuppression and its impact on virus-specific cellular immunity.
Adrian, Egli +8 more
openaire +3 more sources
Role of BK human polyomavirus in cancer [PDF]
Human polyomaviruses (HPyV), which are small DNA viruses classified into the polyomaviridae family, are widely distributed in human populations. Thirteen distinct HPyVs have been described to date. Some of these viruses have been found in human tumors, suggesting an etiological relationship with cancer.
Levican, Jorge +4 more
openaire +8 more sources
Introduction: : BK polyoma virus nephropathy represents one of the non-immunological causes of renal graft loss with a cumulative incidence between 5 and 10 percent, and a graft loss rate on BK virus nephropathy patients that ranges from 30 to 90 percent
Rodolfo Torres +7 more
doaj +1 more source
The Agnogene of the Human Polyomavirus BK Is Expressed [PDF]
ABSTRACT Primate polyomavirus genomes all contain an open reading frame at the 5′ end of the late coding region called the agnogene. A simian virus 40 agnoprotein with unknown functions has previously been demonstrated. We now show that a BK virus agnoprotein appears in the perinuclear area and cytoplasm late in the infectious cycle.
C H, Rinaldo, T, Traavik, A, Hey
openaire +2 more sources

