Results 21 to 30 of about 6,695 (175)

Prevalence of cytomegalovirus and BK polyoma virus infection in post-renal transplant patients in a tertiary care centre in South India [PDF]

Journal of Nephropathology, 2017
Background: Viral infections are a significant cause of graft loss and dysfunction in kidney transplant recipients. Cytomegalovirus and BK polyomavirus have often been explained as the most common viral etiological agents.
Kevin Manuel, Marie Moses Ambroise, Renu G’Boy Varghese, Ilangovan Veerapan, Georgi Abraham   +4 more
doaj   +1 more source

Should SVGp12 Be Used for JC Polyomavirus Studies? Comment on Prezioso et al. COS-7 and SVGp12 Cellular Models to Study JCPyV Replication and MicroRNA Expression after Infection with Archetypal and Rearranged-NCCR Viral Strains. Viruses 2022, 14, 2070

Viruses, 2022
A recent paper in Viruses investigates the impact of the JC polyomavirus (JCPyV) microRNA on the replication of different JCPyV strains. Unfortunately, one of the cell lines used, the human fetal glial cell line SVGp12, is productively infected by the ...
Stian Henriksen, Christine Hanssen Rinaldo   +1 more
doaj   +1 more source

BK Polyomavirus and the Transplanted Kidney [PDF]

Transplantation, 2016
BK polyomavirus is ubiquitous, with a seropositivity rate of over 75% in the adult population. Primary infection is thought to occur in the respiratory tract, but asymptomatic BK virus latency is established in the urothelium. In immunocompromised host, the virus can reactivate but rarely compromises kidney function except in renal grafts, where it ...
Lamarche, Caroline, Orio, Julie, Collette, Suzon, Senécal, Lynne, Hébert, Marie-Josée, Renoult, Édith, Tibbles, Lee Anne, Delisle, Jean-Sébastien   +7 more
openaire   +2 more sources

Persistently high-level polyomavirus BK replication in the absence of renal function abnormalities in a kidney transplant recipient

Microbiologia Medica, 2016
Polyomavirus-associated nephropathy is an important cause of allograft dysfunction and graft loss after kidney transplantation. Even if histological evaluation is the gold standard for graft study and diagnosis of polyomavirus-associated nephropathy, K ...
Antonio Curtoni, Cristina Costa, Maria Messina, Francesca Sidoti, Andrea Piceghello, Gabriele Bianco, Luigi Biancone, Giuseppe Paolo Segoloni, Rossana Cavallo   +8 more
doaj   +1 more source

Research progress in BK polyomavirus nephropathy [PDF]

Jichu yixue yu linchuang
BK polyomavirus (BKPyV) typically enters host cells through caveolin-mediated endocytosis or clathrin-independent vesicle encapsulation, maintaining clinical latency without symptomatic manifestations.
YANG Dan, YANG Feng
doaj   +1 more source

The Potential Role of BK and JC Polyomaviruses in Urothelial Cancer

The Iraqi Journal of Medical Sciences
Background:    BK and JC polyomaviruses are perceived as the two most common human polyomaviruses (HPyVs). These two viruses inhabit the epithelial surfaces of the bladder and kidney as the primary site of replication and latency.
Kawther A. AlMalaki, Asmaa' B. Al-Obaidi, Haider F. Ghazi   +2 more
doaj   +3 more sources

Polyomavirus infections and its clinical relevance in cancer patients: A Prospective Study

Journal of Infection and Public Health, 2017
Summary: BK and JC polyomaviruses (PyV) have been demonstrated to be associated with the pathogenesis of various human cancers. We aimed to investigate the impact of BK and JC polyomavirus infections on several clinical parameters in different human ...
Samah A. Loutfy, Manar M. Moneer, Salem E. Salem, Emad A. El-Moniem Abada, Entsar A. El-Moniem Ahmed, Lamiaa H. Ibrahim, EL-Chaimaa B. Mohamed   +6 more
doaj   +1 more source

A Cell Culture Model of BK Polyomavirus Persistence, Genome Recombination, and Reactivation

mBio, 2021
BK polyomavirus (BKPyV) generally establishes a persistent subclinical infection in healthy individuals but can cause severe disease in transplant recipients.
Linbo Zhao, Michael J. Imperiale
doaj   +1 more source

Comparison of two RT-qPCR methods targeting BK polyomavirus microRNAs in kidney transplant recipients

Frontiers in Medicine, 2023
BackgroundBK polyomavirus replication leads to progressive tubulointerstitial nephritis and ureteral stenosis, with a considerable risk of subsequent graft failure in kidney transplant recipients. Since specific antiviral therapies are lacking, new tools
Kenza Zoubir, Kenza Zoubir, Véronique Descamps, Véronique Descamps, Aurélien Aubry, Aurélien Aubry, Francois Helle, Catherine Francois, Catherine Francois, Sandrine Castelain, Sandrine Castelain, Etienne Brochot, Etienne Brochot, Baptiste Demey, Baptiste Demey   +14 more
doaj   +1 more source

BK polyomavirus—pathogen, paradigm and puzzle

Nephrology Dialysis Transplantation, 2019
AbstractBK virus is a polyomavirus with seroprevalence rates of 80% in adults. Infection is usually acquired during childhood, and the virus is benign or pathologic depending on immune status. The virus reactivates in immunodeficiency states, mostly among transplant (either kidney or bone marrow) recipients.
Suman Krishna Kotla, Pradeep V Kadambi, Allen R Hendricks, Rebecca Rojas   +3 more
openaire   +2 more sources