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BK polyomavirus-associated nephropathy [PDF]
BK polyomavirus (BKPyV) is a ubiquitous virus residing in the kidney tubules and is clinically significant only in immunocompromised patients. In clinical practice, BKPyV is a causative pathogen of BKPyV associated nephropathy (BKVAN) in kidney allograft recipients or hemorrhagic cystitis of hematopoietic stem cell transplant recipients.
Yo Han Ahn, Hee Gyung Kang
doaj +3 more sources
BK Polyomavirus—Biology, Genomic Variation and Diagnosis [PDF]
The BK polyomavirus (BKPyV), a representative of the family Polyomaviridae, is widespread in the human population. While the virus does not cause significant clinical symptoms in immunocompetent individuals, it is activated in cases of immune deficiency, both pharmacological and pathological.
Jacek Furmaga +2 more
exaly +5 more sources
BK polyomavirus-associated nephropathy occurs in kidney transplant recipients under immunosuppressive treatment. BK polyomavirus is implicated in cancer development and invasion, and case reports of renal cell carcinoma and urothelial carcinoma possibly ...
Noriaki Sato +8 more
doaj +2 more sources
BK polyomavirus: emerging pathogen [PDF]
BK polyomavirus (BKPyV) is a small double-stranded DNA virus that is an emerging pathogen in immunocompromised individuals. BKPyV is widespread in the general population, but primarily causes disease when immune suppression leads to reactivation of latent virus.
Michael J Imperiale
exaly +3 more sources
BK Polyomavirus in Renal Transplantation: Virological Notes for Monitoring and Diagnosis. [PDF]
Polyomavirus-associated nephropathy was first reported over 50 years ago. However, it still represents a cause of renal injury in kidney transplant recipients, particularly in the first two years post-transplantation, with occurrence rates of 1–10%.
Costa C, Sidoti F, Bondi A, Curtoni A.
europepmc +2 more sources
Background BK polyomavirus-associated nephropathy is an important cause of post-transplantation renal failure. We present two cases of BK polyomavirus-associated nephropathy who were submitted to contrasting strategies of clinical follow-up to BK ...
Ana Luisa Figueira Gouvêa +10 more
doaj +2 more sources
Native BK Polyomavirus Nephropathy in an Orthotopic Heart Transplant Patient
BK polyomavirus nephropathy (BKVN) is a common cause of nephropathy in kidney transplant patients and is typically seen within the first year after transplantation.
Zachary M. Thompson MD +5 more
doaj +2 more sources
BK Polyomavirus and Transformation [PDF]
The human BK polyomavirus (PyV) (BKV) was isolated from the urine of a kidney transplant patient with the initials B.K. after cells with nuclear atypia were noted in the urine in the diagnostic workup of an alloureter stenosis. Electron microscopy revealed intranuclear inclusions of nonenveloped viral particles of 40–45-nm diameter suggesting infection
Tina Dalianis, Hans H. Hirsch
core +6 more sources
BK Polyomavirus in Solid Organ Transplantation [PDF]
The human BK polyomavirus (BKV) is the major cause of polyomavirus-associated nephropathy (PyVAN) putting 1-15% of kidney transplant patients at risk of premature allograft failure, but is less common in other solid organ transplants. Because effective antiviral therapies are lacking, screening kidney transplant patients for BKV replication in urine ...
Hirsch, H. H., Randhawa, P.
openaire +5 more sources
A highly potent human antibody neutralizing all serotypes of BK polyomavirus. [PDF]
BK polyomavirus infection poses a significant risk to kidney transplant recipients. Reactivation of dormant virus in the transplanted kidney, triggered by immunosuppression, can lead to BK polyomavirus-associated nephropathy in up to 10% of transplants ...
Weber M +12 more
europepmc +2 more sources

