Results 11 to 20 of about 81,224 (208)
Journal of Medical Case Reports, 2017 Background BK polyomavirus-associated nephropathy is an important cause of post-transplantation renal failure. We present two cases of BK polyomavirus-associated nephropathy who were submitted to contrasting strategies of clinical follow-up to BK ...
Ana Luisa Figueira Gouvêa +10 more
doaj +2 more sources
BK Polyomavirus-Induced Nephropathy in Native Kidney
Cureus, 2023 BK polyomavirus has been well-studied as an opportunistic infection in immunocompromised kidney transplant patients. In the majority of the population, BK polyomavirus establishes a lifelong infection in renal tubular and uroepithelial cells; however, in an immunocompromised state, the virus can reactivate and can lead to BK polyomavirus-associated ...
Munjal, Ripudaman S +3 more
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The Lancet Infectious Diseases, 2003 Polyomavirus hominis 1, better known as BK virus (BKV), infects up to 90% of the general population. However, significant clinical manifestations are rare and limited to individuals with impaired immune functions. BKV has been associated with diverse entities such as haemorrhagic cystitis, ureteric stenosis, vasculopathy, pneumonitis, encephalitis ...
Hirsch HH, Steiger J
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BK Polyomavirus in Solid Organ Transplantation [PDF]
American Journal of Transplantation, 2013 The human BK polyomavirus (BKV) is the major cause of polyomavirus-associated nephropathy (PyVAN) putting 1-15% of kidney transplant patients at risk of premature allograft failure, but is less common in other solid organ transplants. Because effective antiviral therapies are lacking, screening kidney transplant patients for BKV replication in urine ...
Hirsch, H. H., Randhawa, P.
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The human polyomavirus BK: Potential role in cancer [PDF]
Journal of Cellular Physiology, 2005 AbstractIn human cancer, a role has been suggested for the human polyomavirus BK, primarily associated with tubulointerstitial nephritis and ureteric stenosis in renal transplant recipients, and with hemorrhagic cystitis in bone marrow transplant (BMT) recipients.
FIORITI, DANIELA +6 more
openaire +6 more sources
Glucocorticoids Do Not Enhance BK Polyomavirus Replication in Human Renal Proximal Tubular Epithelial Cells In Vitro. [PDF]
Clin Transl SciABSTRACT BK polyomavirus (BKPyV) infection may lead to BKPyV‐associated nephropathy (BKPyVAN) and subsequent graft loss in kidney transplant recipients. Experimental studies have suggested that glucocorticoids (GCs) may enhance BKPyV replication through a steroid‐responsive element within the viral genome.
Moest WT +7 more
europepmc +2 more sources
BK Polyomavirus and Transformation [PDF]
American Journal of Transplantation, 2011 The human BK polyomavirus (PyV) (BKV) was isolated from the urine of a kidney transplant patient with the initials B.K. after cells with nuclear atypia were noted in the urine in the diagnostic workup of an alloureter stenosis. Electron microscopy revealed intranuclear inclusions of nonenveloped viral particles of 40–45-nm diameter suggesting infection
Tina Dalianis, Hans H. Hirsch
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Cytomegalovirus and polyomavirus BK posttransplant [PDF]
Nephrology Dialysis Transplantation, 2007 Virus replication and progression to disease in transplant patients is determined by patient-, graft- and virus-specific factors. This complex interaction is modulated by the net state of immunosuppression and its impact on virus-specific cellular immunity.
Adrian, Egli +8 more
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Role of BK human polyomavirus in cancer [PDF]
Infectious Agents and Cancer, 2018 Human polyomaviruses (HPyV), which are small DNA viruses classified into the polyomaviridae family, are widely distributed in human populations. Thirteen distinct HPyVs have been described to date. Some of these viruses have been found in human tumors, suggesting an etiological relationship with cancer.
Levican, Jorge +4 more
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The Agnogene of the Human Polyomavirus BK Is Expressed [PDF]
Journal of Virology, 1998 ABSTRACT Primate polyomavirus genomes all contain an open reading frame at the 5′ end of the late coding region called the agnogene. A simian virus 40 agnoprotein with unknown functions has previously been demonstrated. We now show that a BK virus agnoprotein appears in the perinuclear area and cytoplasm late in the infectious cycle.
C H, Rinaldo, T, Traavik, A, Hey
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