Results 91 to 100 of about 81,224 (208)
Nonclassical MHC‐I Molecules: Emerging Therapeutic Targets in Next‐Generation Immunotherapy
MedComm, Volume 7, Issue 5, May 2026.Immunotherapies dependent on classical MHC‐I molecules face significant challenges, including extreme polymorphism and frequent downregulation in pathological conditions. This review discusses how nonclassical MHC‐I molecules (HLA‐E, HLA‐F, HLA‐G, CD1, MR1) may potentially circumvent these limitations through restricted genetic diversity, stable ...
Wanlin He, Andrew J. McMichael
wiley +1 more source
, 2001 Diagnosis of polyomavirus BK nephropathy and treatment by low-dose immunosuppression may be optimized by using surrogate markers, such as the detection of viral inclusion bearing cells in the urine and polyomavirus BK DNA in plasma by polymerase chain ...
Nickeleit V +5 more
core +1 more source
, 2022 Ataxia telangiectasia (A-T) is a rare neurodegenerative immunodeficiency syndrome, characterised eponymously by progressive cerebellar ataxia and telangiectatic vessels, most often cutaneous. A-T displays autosomal recessive inheritance, is characterised
Perry, C, Kimble, R
core +1 more source
Transplantation: Polyomavirus Nephropathy and the Risk of Specific Immunosuppression Regimens
The Scientific World Journal, 2006 BK virus is ubiquitously present in the latent state in humans, and awareness of the importance of BK polyomavirus is emerging among the kidney transplant community.
Christine Wu +2 more
doaj +1 more source
Surveillance of polyomavirus BK in relation to immunosuppressive therapy in kidney transplantation
Microbiologia Medica, 2012 Introduction. Reactivation of polyomavirus BK in kidney transplant recipients has been associated to the development of nephropathy (polyomavirus-associated nephropathy, PVAN), possibly leading to the loss of the transplanted organ.
Cristina Costa +8 more
doaj +1 more source
Posoleucel for BK Polyomavirus in Kidney Transplant Recipients. [PDF]
J Am Soc NephrolWilhelm M, Geng A, Schaub S, Hirsch HH.
europepmc +3 more sources
Paediatric renal transplantation: Paediatric surgeons' perspective
Surgical Practice, Volume 30, Issue 2, Page 117-122, May 2026.Abstract Renal transplantation is the most effective treatment for paediatric end‐stage renal disease (ESRD), offering advantages in survival, growth and neurocognitive development that surpass other renal replacement therapies (RRT). The paediatric setting, however, introduces distinct complexities that distinguish it from adult practice.
Adrian Chi‐heng Fung +3 more
wiley +1 more source
JC polyomavirus-encoded miRNA jcv-miR-J1-5p downregulates BK polyomavirus infection
International audienceBK and JC Polyomavirus are closely related and establish persistence in infected subjects. Recent studies suggest that JC Polyomavirus replication prevents BK Polyomavirus-related pathologies in kidney transplant recipients.
Francois, Catherine +7 more
core +1 more source
The description of molecular studies analyzing clinically diagnosed BK polyomavirus nephropathy.
, 2023 The description of molecular studies analyzing clinically diagnosed BK polyomavirus nephropathy.
Motoko Yanagita (134965) +8 more
core +1 more source
Late BK Nephropathy 15 years post kidney transplant following chemotherapy: A case report
IDCasesBK Polyomavirus (BKPyV) is an important risk factor for premature graft loss following kidney transplant. Current practice guidelines recommend screening for BK virus DNA for 2 years after kidney transplant as the risk of BK Polyomavirus associated ...
Anum Hamiduzzaman +5 more
doaj +1 more source