Results 41 to 50 of about 15,097 (209)

Prevalence of cytomegalovirus and BK polyoma virus infection in post-renal transplant patients in a tertiary care centre in South India [PDF]

Journal of Nephropathology, 2017
Background: Viral infections are a significant cause of graft loss and dysfunction in kidney transplant recipients. Cytomegalovirus and BK polyomavirus have often been explained as the most common viral etiological agents.
Kevin Manuel, Marie Moses Ambroise, Renu G’Boy Varghese, Ilangovan Veerapan, Georgi Abraham   +4 more
doaj   +1 more source

Optimization of Adcitmer, a Monomethyl-Auristatin E bearing antibody-drug conjugate for the treatment of CD56-expressing cancers

Journal for ImmunoTherapy of Cancer
The cell adhesion protein CD56 has been identified as a potential therapeutic target in several solid tumors and hematological malignancies. Recently, we developed a CD56-directed antibody-drug conjugate (ADC), called Adcitmer and demonstrated its ...
David Schrama, Antoine Touze, Thibault Kervarrec, Mahtab Samimi, Valérie Gouilleux-Gruart, Aurelie Drouin, Laurine Durand, Clara Esnault, Pauline Gaboriaud, Valérie Leblond, Shawk Karim, Morgane Fouché, Christine Dhommée, Christine B Baltus, Fanny Boursin, Nicolas Aubrey, Roland Houben, Serge Guyétant, Audrey Desgranges, Marie Claude Viaud-Massuard   +19 more
doaj   +1 more source

Seroprevalence of fourteen human polyomaviruses determined in blood donors. [PDF]

PLoS ONE, 2018
The polyomavirus family currently includes thirteen human polyomavirus (HPyV) species. In immunocompromised and elderly persons HPyVs are known to cause disease, such as progressive multifocal leukoencephalopathy (JCPyV), haemorrhagic cystitis and ...
Sergio Kamminga, Els van der Meijden, Mariet C W Feltkamp, Hans L Zaaijer   +3 more
doaj   +1 more source

ERK Is a Critical Regulator of JC Polyomavirus Infection [PDF]

Journal of Virology, 2018
ABSTRACTThe human JC polyomavirus (JCPyV) infects the majority of the population worldwide and presents as an asymptomatic, persistent infection in the kidneys. In individuals who are immunocompromised, JCPyV can become reactivated and cause a lytic infection in the central nervous system resulting in the fatal, demyelinating disease progressive ...
Jeanne K, DuShane, Michael P, Wilczek, Colleen L, Mayberry, Melissa S, Maginnis   +3 more
openaire   +2 more sources

Prevalence of IgG antibodies against Malawi polyomavirus in patients with autoimmune diseases and lymphoproliferative disorders subjected to bone marrow transplantation

Frontiers in Immunology
IntroductionHuman polyomaviruses (HPyVs) cause persistent/latent infections in a large fraction of the population. HPyV infections may cause severe diseases in immunocompromised patients.
Jérôme T. J. Nicol, Elisa Mazzoni, Maria Rosa Iaquinta, Raffaella De Pace, Pauline Gaboriaud, Natalia Maximova, Carolina Cason, Eleonora De Martino, Chiara Mazziotta, Pierre Coursaget, Antoine Touzé, Valentina Boz, Manola Comar, Manola Comar, Mauro Tognon, Fernanda Martini, Fernanda Martini   +16 more
doaj   +1 more source

Human Polyomavirus Infection in Renal Allograft Recipients [PDF]

BMJ, 1973
Cytological and virological studies on 74 patients with functioning renal allografts were undertaken to detect polyomavirus infection of the renal tract. Ten patients (13·5%) were excreting polyomavirus. Virus particles were seen in the electron microscope in urine samples from eight patients. B.K.
D V, Coleman, S D, Gardner, A M, Field
openaire   +2 more sources

WU Polyomavirus Infection in Children, Germany

Emerging Infectious Diseases, 2008
To the Editor: The human polyomaviruses JC and BK are known to cause persisting infections, which are usually asymptomatic in immunocompetent patients but may lead to severe disease in those who are immunosuppressed (1). Recently, 2 novel viruses of the family Polyomaviridae were detected in respiratory samples and named KI (2) and WU polyomavirus ...
Florian Neske, Kerstin Blessing, Franziska Ullrich, Anika Pröttel, Hans Wolfgang Kreth, Benedikt Weissbrich   +5 more
openaire   +3 more sources

Recipient–Donor Sex Combinations and Posttransplant Infections: A Swiss Transplant Cohort Study

Transplant Infectious Disease, EarlyView.
In this cohort study of 5033 patients, only the recipient sex, in particularly kidney recipients, was independently associated with an increased risk of infections, when compared to males. These findings indicate that recipient–donor sex combination does not influence short‐term solid organ transplantation outcome.
Christian T. J. Magyar, Charlene P. Gretener, Jaromil Frossard, Katell Mellac, Daniel Sidler, David Reineke, Nicolas J. Mueller, Franz Immer, Christian van Delden, Oriol Manuel, Thorsten Krueger, Nina Khanna, Katia Boggian, Lara Beekman, Cédric Hirzel, Vanessa Banz, Swiss Transplant Cohort Study (STCS)   +16 more
wiley   +1 more source

Small‐molecule inhibitors of JC polyomavirus infection [PDF]

Journal of Peptide Science, 2014
The JC polyomavirus (JCPyV) infects approximately 50% of the human population. In healthy individuals, the infection remains dormant and asymptomatic, but in immuno‐suppressed patients, it can cause progressive multifocal leukoencephalopathy (PML), a potentially fatal demyelinating disease.
Achani, Yatawara, Gabriel, Gaidos, Chamila N, Rupasinghe, Bethany A, O'Hara, Maria, Pellegrini, Walter J, Atwood, Dale F, Mierke   +6 more
openaire   +2 more sources

Human polyomaviruses and cancer: an overview

Clinics, 2018
The name of the family Polyomaviridae, derives from the early observation that cells infected with murine polyomavirus induced multiple (poly) tumors (omas) in immunocompromised mice. Subsequent studies showed that many members of this family exhibit the
José Carlos Mann Prado, Telma Alves Monezi, Aline Teixeira Amorim, Vanesca Lino, Andressa Paladino, Enrique Boccardo   +5 more
doaj   +1 more source