Merkel cell polyomavirus and associated Merkel cell carcinoma [PDF]
Tumour Virus Research, 2022 Merkel cell polyomavirus (MCPyV) is a ubiquitous skin infection that can cause Merkel cell carcinoma (MCC), a highly lethal form of skin cancer with a nearly 50% mortality rate.
June F. Yang, Jianxin You
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Merkel cell polyomavirus and its etiological relationship with skin tumors [PDF]
Anais Brasileiros de Dermatologia, 2023 Viruses have been frequently identified in several human neoplasms, but the etiological role of these viruses in some tumors is still a matter of controversy.
Thiago Rubim Bellott +5 more
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Temporal gating of nuclear import: How Merkel cell polyomavirus exploits the cell cycle for nuclear entry. [PDF]
PLoS PathogensMerkel cell polyomavirus (MCPyV) is a small, DNA tumor virus that is causally linked to an aggressive form of human skin cancer called Merkel cell carcinoma. MCPyV is the only polyomavirus definitively shown to cause cancer in humans, yet little is known
Karen Wang +4 more
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Merkel Cell Polyomavirus: Oncogenesis in a Stable Genome [PDF]
Viruses, 2021 Merkel cell polyomavirus (MCV) is the causative agent for the majority of Merkel cell carcinoma (MCC) cases. Polyomavirus-associated MCC (MCCP) is characterized by the integration of MCV DNA into the tumor genome and a low tumor mutational burden.
Mona M. Ahmed +2 more
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Serum antibodies against mimotopes of Merkel cell polyomavirus oncoproteins detected by a novel immunoassay in healthy individuals and Merkel cell carcinoma patients [PDF]
Microbial BiotechnologyMerkel cell polyomavirus (MCPyV) is the foremost causative factor of Merkel cell carcinoma (MCC), a rare yet highly aggressive skin cancer. Although the evaluation of circulating IgG antibodies against Merkel cell polyomavirus (MCPyV) LT/sT oncoproteins ...
Chiara Mazziotta +12 more
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T-helper Cell-Mediated Proliferation and Cytokine Responses against Recombinant Merkel Cell Polyomavirus-Like Particles [PDF]
, 2011 The newly discovered Merkel Cell Polyomavirus (MCPyV) resides in approximately 80% of Merkel cell carcinomas (MCC). Causal role of MCPyV for this rare and aggressive skin cancer is suggested by monoclonal integration and truncation of large T (LT) viral ...
Chen, Tingting +6 more
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Contemporary Literature Review of Clinical Characteristics and Management of Merkel Cell Carcinoma [PDF]
Liaquat National Journal of Cancer Care, 2022 Merkel cell carcinoma is a rare aggressive, non-melanomatous cutaneous malignancy with rising incidence. It has two distinct etiologies Merkel cell polyomavirus associated and non-associated, usually presents as painless, indurated, solitary violaceous
Laraib Khan +4 more
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Merkel cell carcinoma in an immunosuppressed patient [PDF]
Anais Brasileiros de Dermatologia, 2017 Merkel cell carcinoma is an uncommon neuroendocrine carcinoma with a rising incidence and an aggressive behavior. It predominantly occurs in older patients, with onset occurring at a mean age of 75-80 years.
Heliana Freitas de Oliveira Góes +5 more
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Serological cross-reactivity between Merkel cell polyomavirus and two closely related chimpanzee polyomaviruses. [PDF]
PLoS ONE, 2014 Phylogenetic analyses based on the major capsid protein sequence indicate that Merkel cell polyomavirus (MCPyV) and chimpanzee polyomaviruses (PtvPyV1, PtvPyV2), and similarly Trichodysplasia spinulosa-associated polyomavirus (TSPyV) and the orangutan ...
Jérôme T J Nicol +6 more
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Merkel cell carcinoma arising from postoperative scar: An unusual presentation
Turkderm Turkish Archives of Dermatology and Venereology, 2021 Merkel cell carcinoma (MCC) is an aggressive and uncommon primary cutaneous neuroendocrine cancer. With unknown pathogenesis, immunosuppression, ultraviolet radiation, Merkel cell polyomavirus, and arsenic exposure are the risk factors.
Mualla Polat +4 more
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