Results 21 to 30 of about 7,231 (207)

Epidemiology of Merkel Cell Polyomavirus Infection and Merkel Cell Carcinoma. [PDF]

Cancers (Basel), 2022
Merkel cell polyomavirus (MCPyV) is a ubiquitous virus replicating in human dermal fibroblasts. MCPyV DNA can be detected on healthy skin in 67–90% of various body sites, and intact virions are regularly shed from the skin. Infection occurs early in life, and seropositivity increases from 37 to 42% in 1- to 6-year-olds to 92% in adults.
Silling S, Kreuter A, Gambichler T, Meyer T, Stockfleth E, Wieland U.   +5 more
europepmc   +3 more sources

Merkel cell polyomavirus infection and Merkel cell carcinoma [PDF]

Current Opinion in Virology, 2016
Merkel cell polyomavirus is the only polyomavirus discovered to date that is associated with a human cancer. MCPyV infection is highly prevalent in the general population. Nearly all healthy adults asymptomatically shed MCPyV from their skin. However, in elderly and immunosuppressed individuals, the infection can lead to a lethal form of skin cancer ...
Wei, Liu, Margo, MacDonald, Jianxin, You
openaire   +2 more sources

Epigenetic Dysregulations in Merkel Cell Polyomavirus-Driven Merkel Cell Carcinoma [PDF]

International Journal of Molecular Sciences, 2021
Merkel cell polyomavirus (MCPyV) is a small DNA virus with oncogenic potential. MCPyV is the causative agent of Merkel Cell Carcinoma (MCC), a rare but aggressive tumor of the skin. The role of epigenetic mechanisms, such as histone posttranslational modifications (HPTMs), DNA methylation, and microRNA (miRNA) regulation on MCPyV-driven MCC has ...
Rotondo J. C., Mazziotta C., Lanzillotti C., Tognon M., Martini F.   +4 more
openaire   +3 more sources

Incidence and outcomes of Merkel cell carcinoma related to Merkel cell polyomavirus status in Iceland in 1981-2023. [PDF]

JAAD Int
Vygovska M, Hoyt D, Snyder AM, Jonmundsson T, Khouri A, Sahni DR, Ungar J, Lewin JM, Gulati N, Phelps RG, Sahni VN, Grant-Kels JM, Sigurdsson H, Jonasson JG, Adalsteinsson JA.   +14 more
europepmc   +2 more sources

Primary Merkel cell carcinoma of the salivary gland: a clinicopathologic study of four cases with a review of literature [PDF]

Journal of Pathology and Translational Medicine
Background Primary Merkel cell carcinoma of the salivary gland is currently not listed in the World Health Organization classification. However, cases of Merkel cell type neuroendocrine carcinomas of the salivary gland with perinuclear cytokeratin 20 ...
Gyuheon Choi, Joon Seon Song, Hee Jin Lee, Gi Hwan Kim, Young Ho Jung, Yoon Se Lee, Kyung-Ja Cho   +6 more
doaj   +1 more source

Mining for viral fragments in methylation enriched sequencing data [PDF]

, 2015
Most next generation sequencing experiments generate more data than is required for the experimental set up. For example, methyl-CpG binding domain (MBD) affinity purification based sequencing is often used for DNA-methylation profiling, but up to 30% of
Ed eSchuuring, G. Bea A. Wisman, Klaas eMensaert, Olivier eThas, Renske D. M. Steenbergen, Tim eDe Meyer, Wim eVan Criekinge, Wim eVan Criekinge   +7 more
core   +4 more sources

Merkel cell polyomavirus and Merkel cell carcinoma

Uirusu, 2009
A new polyomavirus, Merkel cell polyomavirus, was identified from Merkel cell carcinoma, a rare skin cancer. Origin of Merkel cell carcinoma is Merkel cell, a neuroendocrine cell in the skin. Merkel cell carcinoma occurs in the skin of head and face of white elders.
Tomoyuki, Nakamura, Harutaka, Katano
openaire   +3 more sources

Newly described human polyomaviruses Merkel Cell, KI and WU are present in urban sewage and may represent potential environmental contaminants

Virology Journal, 2010
Recently, three new polyomaviruses (KI, WU and Merkel cell polyomavirus) have been reported to infect humans. It has also been suggested that lymphotropic polyomavirus, a virus of simian origin, infects humans. KI and WU polyomaviruses have been detected
Carratala Anna, Calgua Byron, Rodriguez-Manzano Jesus, Bofill-Mas Sílvia, Girones Rosina   +4 more
doaj   +1 more source

Perforated gastric metastasis of Merkel cell carcinoma: Case report and review of the literature

Human Pathology: Case Reports, 2017
A 53 year-old Vietnamese male presented with a complaint of a left buttock mass which had grown to 8.0 cm during the past three years. A CT scan revealed the gluteal lesion and a large mass of the stomach.
Darshan Trivedi, MD, PhD, Victoria Collins, MD, Evans Roberts, MD, John Scopetta, MD, Tong Wu, MD, PhD, Byron Crawford, MD, Yukihiro Nakanishi, MD, PhD   +6 more
doaj   +1 more source

No Evidence of Human Polyomavirus 9, WU and KI DNA in Kidney and Urinary Bladder Tumour Tissue Samples [PDF]

, 2016
KAL
Bidiga, László, Csoma, Eszter, Gergely, Lajos, Méhes, Gábor   +3 more
core   +1 more source