Results 41 to 50 of about 5,177 (192)

BKV Agnoprotein Interacts with α-Soluble N-Ethylmaleimide-Sensitive Fusion Attachment Protein, and Negatively Influences Transport of VSVG-EGFP [PDF]

, 2011
Background: The human polyomavirus BK (BKV) infects humans worldwide and establishes a persistent infection in the kidney. The BK virus genome encodes three regulatory proteins, large and small tumor-antigen and the agnoprotein, as well as the capsid ...
Johannessen, M., Mona Johannessen, Walquist, Mari, Moens, Ugo, Walquist Mari, Spang Anne, Mari Walquist, Moens Ugo, Anne Spang, Gerits, N., Spang, Anne, Johannessen, Mona, Marte Dragset, Gerits Nancy, Johannessen Mona, Nancy Gerits, Ugo Moens, Dragset Marte, Walquist, M., Gerits, Nancy, Dragset, Marte Singsås, Dragset, M., Spang, A., Moens, U.   +23 more
core   +1 more source

Regulation of Polyomavirus Transcription by Viral and Cellular Factors

Viruses, 2020
Polyomavirus infection is widespread in the human population. This family of viruses normally maintains latent infection within the host cell but can cause a range of human pathologies, especially in immunocompromised individuals.
June F. Yang, Jianxin You
doaj   +1 more source

Merkel Cell Polyomavirus Infection and Detection [PDF]

Journal of Visualized Experiments, 2019
Merkel cell polyomavirus (MCPyV) infection can lead to Merkel cell carcinoma (MCC), a highly aggressive form of skin cancer. Mechanistic studies to fully investigate MCPyV molecular biology and oncogenic mechanisms have been hampered by a lack of adequate cell culture models.
Wei, Liu, Nathan A, Krump, Christopher B, Buck, Jianxin, You   +3 more
openaire   +2 more sources

Infectious Entry of Merkel Cell Polyomavirus [PDF]

Journal of Virology, 2018
MCPyV is the first polyomavirus directly implicated in the development of an aggressive human cancer, Merkel cell carcinoma (MCC). Although MCPyV is constantly shed from healthy skin, the MCC incidence increases among aging and immunocompromised individuals.
Becker, Miriam, Dominguez, Melissa, Greune, Lilo, Soria-Martinez, Laura, Pfleiderer, Moritz M., Schowalter, Rachel, Buck, Christopher B., Blaum, Bärbel S., Alexander Schmidt, M., Schelhaas, Mario   +9 more
openaire   +2 more sources

Vulvar neuroendocrine carcinoma that is independent of merkel cell polyomavirus and human papillomavirus suggests endometrial cancer recurrence: a case report

BMC Endocrine Disorders, 2022
Background Vulvar neuroendocrine carcinomas with small cell morphology need an appropriate differential diagnosis with respect to primary Merkel cell carcinomas, primary small cell neuroendocrine carcinomas, and secondary/metastatic carcinomas.
Tomoko Hirakawa, Mitsutake Yano, Haruto Nishida, Shimpei Sato, Kaei Nasu   +4 more
doaj   +1 more source

Merkel Cell Polyomavirus DNA in Respiratory Specimens from Children and Adults

Emerging Infectious Diseases, 2009
Merkel cell polyomavirus (MCPyV) DNA was detected in 7 (1.3%) of 526 respiratory tract samples from patients in Australia with upper or lower respiratory tract symptoms.
Seweryn Bialasiewicz, Stephen B. Lambert, David M. Whiley, Michael D. Nissen, Theo P. Sloots   +4 more
doaj   +1 more source

Detection of Merkel cell polyomavirus in epidermodysplasia-verruciformis-associated skin neoplasms [PDF]

, 2010
BACKGROUNd: Epidermodysplasia verruciformis (EV) is a rare genodermatosis that is characterized by susceptibility to infection with specific human papillomavirus (HPV) genotypes.
Palmedo, G, Cribier, B, Burger, B, L. Schärer, Schmid, M, K.D. Mertz, Pfaltz, M, Schmid, M., W. Kempf, Fernández Figueras, M T, Pfaltz, M., M. Schmid, Itin, P., B. Cribier, Schärer, L, H. Kutzner, Mertz, K D, Mertz, K. D., Kutzner, H., Fernández Figueras, M. T., B. Burger, P. Itin, Burger, B., M. Pfaltz, G. Palmedo, Schärer, L., Palmedo, G., Kutzner, H, Kempf, W., M.T. Fernández Figueras, Cribier, B., Kempf, W, Itin, P   +32 more
core   +1 more source

Merkel cell polyomavirus is not detected in mesotheliomas [PDF]

Journal of Clinical Virology, 2010
Merkel cell polyomavirus (MCPyV) is the first polyoma virus consistently linked to the etiology of a human cancer. Serological studies indicate that the virus is commonly acquired in childhood, with seroprevalence reaching 50% or higher among young adults.
Kishor, Bhatia, Rama, Modali, James J, Goedert   +2 more
openaire   +2 more sources

Neurocan expression associates with better survival and viral positivity in Merkel cell carcinoma.

PLoS ONE, 2023
Merkel cell carcinoma (MCC) is a rare cutaneous neuroendocrine carcinoma that is frequently divided into Merkel cell polyomavirus negative and positive tumors due their distinct genomic and transcriptomic profiles, and disease outcomes.
Marko Salmikangas, Maria Laaksonen, Henrik Edgren, Marco Salgado, Anu Suoranta, Pirkko Mattila, Virve Koljonen, Tom Böhling, Harri Sihto   +8 more
doaj   +1 more source

Merkel Cell Polyomavirus Large T Antigen Induces Cellular Senescence for Host Growth Arrest and Viral Genome Persistence through Its Unique Domain

Cells, 2023
Senescent cells accumulate in the host during the aging process and are associated with age-related pathogeneses, including cancer. Although persistent senescence seems to contribute to many aspects of cellular pathways and homeostasis, the role of ...
Alexander M. Pham, Luz E. Ortiz, Aron E. Lukacher, Hyun Jin Kwun   +3 more
doaj   +1 more source