Results 51 to 60 of about 5,177 (192)
JC and BK polyomavirus-like particles as targets of innate and adaptive humoral immunity [PDF]
, 2015 JC polyomavirus (JCPyV) and BK polyomavirus (BKPyV) were identified as the first of now more than 12 human polyomaviruses (HPyVs). The average JCPyV and BKPyV seroprevalence rates in adults are 70% and 90%, respectively. After asymptomatic infection both
Kardas, Piotr
core +1 more source
Merkel cell carcinoma: epidemiology, clinical features, diagnosis and treatment of a rare disease
Anais Brasileiros de Dermatologia, 2023 Merkel cell carcinoma is a rare skin cancer with neuroendocrine differentiation. The risk factors include sun exposure, advanced age, immunosuppression (such as transplant recipients, patients with lymphoproliferative neoplasms, or patients with HIV ...
Stella Meireles Siqueira +4 more
doaj +1 more source
, 2019 This dataset is about analyses of two Merkel cell polyomavirus (MCPyV)-negative and two MCPyV–positive Merkel cell lines secretomic proteins.Abstract: Extracellular vesicles or exosomes constitute an evolutionarily conserved mechanism of intercellular ...
Konstantinell, Aelita Gloria Virginia
core +1 more source
Taking the Scenic Route: Polyomaviruses Utilize Multiple Pathways to Reach the Same Destination
Viruses, 2020 Members of the Polyomaviridae family differ in their host range, pathogenesis, and disease severity. To date, some of the most studied polyomaviruses include human JC, BK, and Merkel cell polyomavirus and non-human subspecies murine and simian virus 40 ...
Colleen L. Mayberry, Melissa S. Maginnis
doaj +1 more source
Inflammatory Monocytes Are a Reservoir for Merkel Cell Polyomavirus [PDF]
Journal of Investigative Dermatology, 2010 Merkel cell polyomavirus (MCPyV) is a recently discovered virus that is implicated in the oncogenesis of Merkel cell carcinoma (MCC). The route of dissemination and the reservoir(s) of MCPyV within the human body have not yet been identified. In this study we describe two patients with multiple MCPyV-positive inflammatory and neoplastic skin lesions at
Mertz, K D +4 more
openaire +3 more sources
Diagnostic Methods for and Clinical Pictures of Polyomavirus Primary Infections in Children, Finland
Emerging Infectious Diseases, 2014 We used comprehensive serodiagnostic methods (IgM, IgG, and IgG avidity) and PCR to study Merkel cell polyomavirus and trichodysplasia spinulosa-associated polyomavirus infections in children observed from infancy to adolescence. Comparing seroconversion
Tingting Chen +13 more
doaj +1 more source
Journal of Cutaneous Pathology, EarlyView.ABSTRACT Merkel cell carcinoma (MCC) is a rare, aggressive cutaneous neuroendocrine carcinoma that typically arises in sun‐exposed skin of older or immunosuppressed patients. Combined or collision tumors involving MCC and other cutaneous malignancies are uncommon, and tumors exhibiting more than two distinct malignant phenotypes are exceptionally rare.
Zeinab Khalil +2 more
wiley +1 more source
Extracutaneous Merkel cell carcinomas harbor polyomavirus DNA
, 2012 Merkel cell carcinoma is a neuroendocrine tumor, with characteristic morphological and immunohistochemical features. Originally reported as primary carcinoma of skin, it has been described in numerous other sites such as lymph nodes, oral cavity, breast,
ASIOLI, SOFIA +3 more
core +1 more source
Transplant International, 2023 Long-term risk for malignancy is higher among solid organ transplant (SOT) recipients compared to the general population. Four non-hepatitis viruses have been recognized as oncogenic in SOT recipients—EBV, cause of EBV-associated lymphoproliferative ...
Alaa Atamna +4 more
doaj +1 more source
International Journal of Cancer, Volume 158, Issue 12, Page 3268-3278, 15 June 2026.What's new? TRIM25 is known for its role in antiviral immunity and association with poor prognosis in various cancers. This study reveals an association between high TRIM25 expression and Merkel cell polyomavirus positivity in Merkel cell carcinoma.
Klaus W. Fagerstedt +6 more
wiley +1 more source