Results 51 to 60 of about 7,231 (207)

Merkel cell carcinoma: epidemiology, clinical features, diagnosis and treatment of a rare disease

Anais Brasileiros de Dermatologia, 2023
Merkel cell carcinoma is a rare skin cancer with neuroendocrine differentiation. The risk factors include sun exposure, advanced age, immunosuppression (such as transplant recipients, patients with lymphoproliferative neoplasms, or patients with HIV ...
Stella Meireles Siqueira, Gabriella Campos-do-Carmo, Alexssandra Lima Siqueira dos Santos, Cícero Martins, Andreia Cristina de Melo   +4 more
doaj   +1 more source

High viral load of Merkel cell polyomavirus DNA sequences in Langerhans cell sarcoma tissues. [PDF]

, 2014
International audienceBACKGROUND: Langerhans cell (LC) sarcoma (LCS) is a high-grade neoplasm with overtly malignant cytologic features and an LC phenotype.
A Kanik, A Kubo, C Pancaldi, CET da Costa, D Schrama, D Tortorella, DP O'Malley, E Izmailova, Francis Jaubert, H Feng, Hirokazu Nakamine, I Grosjean, I Murakami, Ichiro Murakami, J Banchereau, J Engelmayer, Jean Gogusev, Katsuyoshi Takata, Kazuhiko Hayashi, KD Mertz, KJ Busam, M Matsushita, M Shamoto, M Shuda, Masako Kato, Michiko Matsushita, Mitsunori Yamakawa, R Jaffe, S Kuwamoto, S Kuwamoto, S Weitzman, Satoshi Kuwamoto, Shu Nakamoto, Tadashi Yoshino, Takashi Oka, Takeshi Iwasaki, X Sastre-Garau, Yasushi Horie, YL Tolstov   +38 more
core   +4 more sources

Taking the Scenic Route: Polyomaviruses Utilize Multiple Pathways to Reach the Same Destination

Viruses, 2020
Members of the Polyomaviridae family differ in their host range, pathogenesis, and disease severity. To date, some of the most studied polyomaviruses include human JC, BK, and Merkel cell polyomavirus and non-human subspecies murine and simian virus 40 ...
Colleen L. Mayberry, Melissa S. Maginnis
doaj   +1 more source

Detection and characterization of two chimpanzee polyomavirus genotypes from different subspecies [PDF]

, 2010
The complete nucleotide sequences of three chimpanzee polyomavirus genetic variants were determined. Phylogenetic analysis indicated that the viruses form two different genotypes of ChPyV.
Ilona Deuzing, Zahra Fagrouch, Marlous J Groenewoud, Henk Niphuis, Ivanela Kondova, Willy Bogers, Ernst J Verschoor   +6 more
core   +1 more source

The Role of Human Papillomaviruses and Polyomaviruses in BRAF-Inhibitor Induced Cutaneous Squamous Cell Carcinoma and Benign Squamoproliferative Lesions [PDF]

, 2018
Background: Human papillomavirus (HPV) has long been proposed as a cofactor in the pathogenesis of cutaneous squamous cell carcinoma (cSCC). More recently, the striking clinico-pathological features of cSCCs that complicate treatment of metastatic ...
Andrew P. South, Catherine A. Harwood, Catherine A. Harwood, Charlotte M. Proby, Els Van der Meijden, Gareth J. Inman, Hasan Rizvi, Heather Griffin, Irene M. Leigh, John Doorbar, Karin J. Purdie, Mariet C. Feltkamp, Mary Sommerlad   +12 more
core   +6 more sources

Mutational Analysis of Merkel Cell Carcinoma [PDF]

, 2014
Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine malignancy that is associated with a poor prognosis. The pathogenesis of MCC is not well understood, and despite a recent plethora of mutational analyses, we have yet to find a set of ...
Cusack, James C., Erstad, Derek J.
core   +2 more sources

Diagnostic Methods for and Clinical Pictures of Polyomavirus Primary Infections in Children, Finland

Emerging Infectious Diseases, 2014
We used comprehensive serodiagnostic methods (IgM, IgG, and IgG avidity) and PCR to study Merkel cell polyomavirus and trichodysplasia spinulosa-associated polyomavirus infections in children observed from infancy to adolescence. Comparing seroconversion
Tingting Chen, Laura Tanner, Ville Simell, Lea Hedman, Marjaana Mäkinen, Mohammadreza Sadeghi, Riitta Veijola, Heikki Hyöty, Jorma Ilonen, Mikael Knip, Jorma Toppari, Olli Simell, Maria Söderlund-Venermo, Klaus Hedman   +13 more
doaj   +1 more source

Merkel Cell Carcinoma With Divergent Differentiation—Or Something Else? A Triphasic Cutaneous Carcinoma With Lineage Plasticity

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Merkel cell carcinoma (MCC) is a rare, aggressive cutaneous neuroendocrine carcinoma that typically arises in sun‐exposed skin of older or immunosuppressed patients. Combined or collision tumors involving MCC and other cutaneous malignancies are uncommon, and tumors exhibiting more than two distinct malignant phenotypes are exceptionally rare.
Zeinab Khalil, Hozaifa Elameen, Ahmed K. Alomari   +2 more
wiley   +1 more source

Inflammatory Monocytes Are a Reservoir for Merkel Cell Polyomavirus [PDF]

Journal of Investigative Dermatology, 2010
Merkel cell polyomavirus (MCPyV) is a recently discovered virus that is implicated in the oncogenesis of Merkel cell carcinoma (MCC). The route of dissemination and the reservoir(s) of MCPyV within the human body have not yet been identified. In this study we describe two patients with multiple MCPyV-positive inflammatory and neoplastic skin lesions at
Mertz, K D, Junt, T, Schmid, M, Pfaltz, M, Kempf, W   +4 more
openaire   +3 more sources

Prevention of Oncogenic Gammaherpesvirinae (EBV and HHV8) Associated Disease in Solid Organ Transplant Recipients

Transplant International, 2023
Long-term risk for malignancy is higher among solid organ transplant (SOT) recipients compared to the general population. Four non-hepatitis viruses have been recognized as oncogenic in SOT recipients—EBV, cause of EBV-associated lymphoproliferative ...
Alaa Atamna, Alaa Atamna, Dafna Yahav, Dafna Yahav, Cédric Hirzel   +4 more
doaj   +1 more source