Results 51 to 60 of about 4,878,012 (192)

Detection of Merkel cell polyomavirus in epidermodysplasia-verruciformis-associated skin neoplasms [PDF]

, 2010
BACKGROUNd: Epidermodysplasia verruciformis (EV) is a rare genodermatosis that is characterized by susceptibility to infection with specific human papillomavirus (HPV) genotypes.
Palmedo, G, Cribier, B, Burger, B, L. Schärer, Schmid, M, K.D. Mertz, Pfaltz, M, Schmid, M., W. Kempf, Fernández Figueras, M T, Pfaltz, M., M. Schmid, Itin, P., B. Cribier, Schärer, L, H. Kutzner, Mertz, K D, Mertz, K. D., Kutzner, H., Fernández Figueras, M. T., B. Burger, P. Itin, Burger, B., M. Pfaltz, G. Palmedo, Schärer, L., Palmedo, G., Kutzner, H, Kempf, W., M.T. Fernández Figueras, Cribier, B., Kempf, W, Itin, P   +32 more
core   +2 more sources

Neurocan expression associates with better survival and viral positivity in Merkel cell carcinoma.

PLoS ONE, 2023
Merkel cell carcinoma (MCC) is a rare cutaneous neuroendocrine carcinoma that is frequently divided into Merkel cell polyomavirus negative and positive tumors due their distinct genomic and transcriptomic profiles, and disease outcomes.
Marko Salmikangas, Maria Laaksonen, Henrik Edgren, Marco Salgado, Anu Suoranta, Pirkko Mattila, Virve Koljonen, Tom Böhling, Harri Sihto   +8 more
doaj   +1 more source

Replication Data for: Secretomic analysis of extracellular vesicles originating from polyomavirus-negative and polyomavirus-positive Merkel cell carcinoma cell lines

, 2019
This dataset is about analyses of two Merkel cell polyomavirus (MCPyV)-negative and two MCPyV–positive Merkel cell lines secretomic proteins.Abstract: Extracellular vesicles or exosomes constitute an evolutionarily conserved mechanism of intercellular ...
Konstantinell, Aelita Gloria Virginia
core   +1 more source

Taking the Scenic Route: Polyomaviruses Utilize Multiple Pathways to Reach the Same Destination

Viruses, 2020
Members of the Polyomaviridae family differ in their host range, pathogenesis, and disease severity. To date, some of the most studied polyomaviruses include human JC, BK, and Merkel cell polyomavirus and non-human subspecies murine and simian virus 40 ...
Colleen L. Mayberry, Melissa S. Maginnis
doaj   +1 more source

Merkel cell carcinoma: epidemiology, clinical features, diagnosis and treatment of a rare disease

Anais Brasileiros de Dermatologia, 2023
Merkel cell carcinoma is a rare skin cancer with neuroendocrine differentiation. The risk factors include sun exposure, advanced age, immunosuppression (such as transplant recipients, patients with lymphoproliferative neoplasms, or patients with HIV ...
Stella Meireles Siqueira, Gabriella Campos-do-Carmo, Alexssandra Lima Siqueira dos Santos, Cícero Martins, Andreia Cristina de Melo   +4 more
doaj   +1 more source

Diagnostic Methods for and Clinical Pictures of Polyomavirus Primary Infections in Children, Finland

Emerging Infectious Diseases, 2014
We used comprehensive serodiagnostic methods (IgM, IgG, and IgG avidity) and PCR to study Merkel cell polyomavirus and trichodysplasia spinulosa-associated polyomavirus infections in children observed from infancy to adolescence. Comparing seroconversion
Tingting Chen, Laura Tanner, Ville Simell, Lea Hedman, Marjaana Mäkinen, Mohammadreza Sadeghi, Riitta Veijola, Heikki Hyöty, Jorma Ilonen, Mikael Knip, Jorma Toppari, Olli Simell, Maria Söderlund-Venermo, Klaus Hedman   +13 more
doaj   +1 more source

Inflammatory Monocytes Are a Reservoir for Merkel Cell Polyomavirus [PDF]

Journal of Investigative Dermatology, 2010
Merkel cell polyomavirus (MCPyV) is a recently discovered virus that is implicated in the oncogenesis of Merkel cell carcinoma (MCC). The route of dissemination and the reservoir(s) of MCPyV within the human body have not yet been identified. In this study we describe two patients with multiple MCPyV-positive inflammatory and neoplastic skin lesions at
Mertz, K D, Junt, T, Schmid, M, Pfaltz, M, Kempf, W   +4 more
openaire   +3 more sources

Merkel cell carcinoma: an updated guide for pathologists

Histopathology, EarlyView.
Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine carcinoma for which the differential diagnosis can include other small cell malignancies (especially metastatic small cell carcinoma) or cutaneous carcinoma. Morphologic and immunophenotypic aberrancies in MCC can increase diagnostic challenge.
Paul W. Harms
wiley   +1 more source

Extracutaneous Merkel cell carcinomas harbor polyomavirus DNA

, 2012
Merkel cell carcinoma is a neuroendocrine tumor, with characteristic morphological and immunohistochemical features. Originally reported as primary carcinoma of skin, it has been described in numerous other sites such as lymph nodes, oral cavity, breast,
ASIOLI, SOFIA, EUSEBI, VINCENZO, RAGAZZI, MOIRA, DE BIASE, DARIO   +3 more
core   +1 more source

Merkel Cell Carcinoma With Divergent Differentiation—Or Something Else? A Triphasic Cutaneous Carcinoma With Lineage Plasticity

Journal of Cutaneous Pathology, Volume 53, Issue 11, Page 994-999, November 2026.
ABSTRACT Merkel cell carcinoma (MCC) is a rare, aggressive cutaneous neuroendocrine carcinoma that typically arises in sun‐exposed skin of older or immunosuppressed patients. Combined or collision tumors involving MCC and other cutaneous malignancies are uncommon, and tumors exhibiting more than two distinct malignant phenotypes are exceptionally rare.
Zeinab Khalil, Hozaifa Elameen, Ahmed K. Alomari   +2 more
wiley   +1 more source