Results 71 to 80 of about 4,032 (162)

Socioeconomic Disparities Affect Cancer‐Specific Survival After Surgery for Localized Merkel Cell Carcinoma: A Population‐Based Retrospective Analysis in the United States

Dermatologic Therapy, Volume 2026, Issue 1, 2026.
Background Merkel cell carcinoma (MCC) is a rare and highly aggressive skin tumor with an increasing incidence over the past few decades. However, limited research has examined the association between socioeconomic status (SES) and cancer‐specific survival (CSS) in MCC. Methods Our cohort study analyzed data from the Surveillance, Epidemiology, and End
Yiding Xiao, Zhujun Li, Bozhi Hu, Hailin Zhang, Suraiya Saleem   +4 more
wiley   +1 more source

The Role of APOBEC3B in Cancer: Mechanisms, Clinical Challenges, and Therapeutic Opportunities

Human Mutation, Volume 2026, Issue 1, 2026.
Apolipoprotein B mRNA editing enzyme catalytic polypeptide‐like 3B (APOBEC3B, A3B) is a key cytidine deaminase that induces genomic instability and clonal evolution in diverse malignancies. Although A3B plays a key role in the onset and advancement of various cancers, a comprehensive model bridging its multifaceted mechanisms and clinical translation ...
Fengfeng Zhou, Weili Chen, Liqin Ruan, Run Shi   +3 more
wiley   +1 more source

The Presence and Tissue Distribution of Fusobacterium nucleatum and Porphyromonas gingivalis in Oral Squamous Cell Carcinoma

International Journal of Dentistry, Volume 2026, Issue 1, 2026.
Purpose The aim of our study was to investigate the presence of Fusobacterium nucleatum (FN) and Porphyromonas gingivalis (PG) in oral cancer samples, to possibly reveal their potential contribution to oral cancer. Methods We examined a total of 48 histological specimens, of which 42 were squamous cell carcinomas, two verrucous carcinomas (VCs), and ...
Juho-Matti Huhtala, Marwa Buaoud, Ahmed Musrati, Katariina Piiparinen, Auli Suominen, Caj Haglund, Jaana Hagström, Jaana Willberg, Zhengrui Li   +8 more
wiley   +1 more source

The Human Polyomavirus Middle and Alternative T-Antigens; Thoughts on Roles and Relevance to Cancer

Frontiers in Microbiology, 2018
Approximately 15–20% of human cancer is related to infection, which renders them potentially preventable by antimicrobial or antiviral therapy. Human polyomaviruses (PyVs) are relevant in this regard, as illustrated by the involvement of Merkel cell ...
Els van der Meijden, Mariet Feltkamp
doaj   +1 more source

Prognostic Factors Influencing Oncologic Outcomes in Merkel Cell Carcinoma: A Retrospective Population‐Based Cohort Study

Journal of Skin Cancer, Volume 2026, Issue 1, 2026.
Aim/Objectives Merkel cell carcinoma (MCC) is a rare, aggressive neuroendocrine skin cancer with a poorly understood etiology and lacking high‐level evidence to guide its management. This study examined the presentation and outcome related to MCC treatment at a Canadian center.
Megan McDonald, Vibhay Pareek, Frances-Claire Eichorn, Arbind Dubey, Alok Pathak, Richa Sharma   +5 more
wiley   +1 more source

Detection of Merkel Cell Carcinoma Polyomavirus in Mucosal Merkel Cell Carcinoma

International Journal of Surgical Pathology, 2010
A 61-year-old woman presented with solitary lymphadenopathy suspicious for lymphoma. An excisional biopsy of a right inguinal lymph node demonstrated metastatic Merkel cell carcinoma (MCC). No skin lesions were detected, but a primary nasopharyngeal mass was identified. A microscopic examination of the nasopharyngeal tumor and the lymph node metastasis
Karen N, Wu, Peter A, McCue, Adam, Berger, Joseph R, Spiegel, Zi-Xuan, Wang, Agnieszka K, Witkiewicz   +5 more
openaire   +3 more sources

Merkel cell carcinoma following photodynamic therapy in a high-risk patient

Dermatology Reports
Dear Editor, Merkel cell carcinoma (MCC) is defined as a rare but highly aggressive skin cancer originating from neuroendocrine cells. Clinically, it usually appears as a rapidly growing, solid, asymptomatic, redviolaceous nodule.
Francesca Polita, Massimiliano Mengarino, Valentina Carelli, Esther Hanspeter, Rosita Saraceno   +4 more
doaj   +1 more source

Rak neuroendokrynny skóry (Merkla) – aktualne poglądy na patogenezę oraz metody leczenia

Przegląd Dermatologiczny, 2011
Merkel cell carcinoma (MCC) is a rare, aggressive neuroendocrine skincancer localized mostly on exposed, sun-damaged skin – on the headand neck. Although rapidly increasing incidence of MCC is observed,the pathogenesis of the tumour is unclear. Diagnosis
Beata Sosada, Ligia Brzezińska-Wcisło
doaj  

A review of the epidemiology and treatment of Merkel cell carcinoma

Clinics, 2011
Merkel cell carcinoma is a very rare and aggressive neoplasm. Due to its rarity, therapeutic guidelines are not well established, especially for regionally advanced disease.
João Pedreira Duprat, Gilles Landman, João Victor Salvajoli, Eduard Rene Brechtbühl   +3 more
doaj   +1 more source

Discovery of a new human polyomavirus associated with trichodysplasia spinulosa in an immunocompromized patient.

PLoS Pathogens, 2010
The Polyomaviridae constitute a family of small DNA viruses infecting a variety of hosts. In humans, polyomaviruses can cause infections of the central nervous system, urinary tract, skin, and possibly the respiratory tract.
Els van der Meijden, René W A Janssens, Chris Lauber, Jan Nico Bouwes Bavinck, Alexander E Gorbalenya, Mariet C W Feltkamp   +5 more
doaj   +1 more source