Results 81 to 90 of about 4,878,012 (192)

RB1 inactivation in cutaneous carcinomas

Histopathology, Volume 88, Issue 4, Page 769-789, March 2026.
Among skin carcinomas, recurrent RB1 inactivation is observed in Merkel cell carcinoma, in a subset of squamous cell carcinoma with bowenoid morphology, in sebaceous carcinoma and in the recently described Wnt/beta‐catenin rosette‐forming carcinoma.
Tiffany Liv, Antoine Touzé, David Schrama, Serge Guyétant, Mahtab Samimi, Michael T Tetzlaff, Benjamin A Wood, Paul W Harms, Thibault Kervarrec   +8 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, Volume 20, Issue 2, Page 331-347, February 2026.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Supplementary Data 1 from Merkel Cell Polyomavirus Infection, Large T Antigen, Retinoblastoma Protein and Outcome in Merkel Cell Carcinoma

, 2011
Supplementary Data 1 from Merkel Cell Polyomavirus Infection, Large T Antigen, Retinoblastoma Protein and Outcome in Merkel Cell ...
Virve Koljonen (3879877), Heli Kukko (14983385), Tom Böhling (92476), Harri Sihto (3627110), Risto Sankila (14983388), Heikki Joensuu (43841)   +5 more
core   +1 more source

Merkel Cell Carcinoma: A Complete Response to Avelumab Immunotherapy

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Merkel cell carcinoma is an aggressive form of cancer with poor prognosis, particularly for individuals deemed unsuitable for surgical resection. With new immunotherapy agents being used alone or as an adjuvant treatment, improving long term outcomes are being seen, even for those deemed to be treated with palliative intent.
Eamonn Byrne, Mel Corbett, Eoin Conlon, Fergal O'Duffy   +3 more
wiley   +1 more source

Generation of Merkel cell polyomavirus (MCV)-like particles and their application to detection of MCV antibodies. [PDF]

, 2010
The genome of a new human polyomavirus, known as Merkel cell polyomavirus (MCV), has recently been reported to be integrated within the cellular DNA of Merkel cell carcinoma (MCC), a rare human skin cancer.
S. Guyetant, Maxime Fleury, Nicolas Combelas, Annabel Maruani, Touz\ue9, Antoine, Baay, Marc, Coursaget, Pierre, Marc Baay, Antoine Touzé, Gaitan, Julien, Cazal, Rapha\uebl, Fleury, Maxime J., Pierre Yves Sizaret, Tognon, Mauro, Arnold, Françoise, M. Tognon, Raphaël Cazal, Pierre Coursaget, F. Arnold, R. Cazal, P.Y. Sizaret, Maruani, Annabel, P. Y. Sizaret, Touzé, Antoine, Arnold, Fran\ue7oise, Serge Guyetant, P. Coursaget, Julien Gaitan, Cazal, Raphaël, A. Maruani, A. Touzé, Françoise Arnold, Guyetant, Serge, Fleury, Maxime J J, M. J. Fleury, M. Baay, J. Gaitan, Combelas, Nicolas, Sizaret, Pierre-Yves, M. Fleury, N. Combelas   +40 more
core   +1 more source

Harnessing viral footprints in circulating free DNA (cfDNA) for early cancer detection: A focus on liquid‐biopsy‐based screening

International Journal of Cancer, Volume 158, Issue 3, Page 511-526, 1 February 2026.
Abstract Viral infections play a significant role in cancer development, making detecting viral signatures a promising approach for early cancer diagnosis. Circulating free DNA (cfDNA), released into the bloodstream by tumors and other cells, has emerged as a powerful biomarker for non‐invasive cancer screening.
Richard Donkor Amponsah, Emmanuel Addai Gyabaah, Moro Amidu, Zhao Cheng, Fazlur Rahman Talukdar   +4 more
wiley   +1 more source

Supplementary Data 3 from Merkel Cell Polyomavirus Infection, Large T Antigen, Retinoblastoma Protein and Outcome in Merkel Cell Carcinoma

, 2011
Supplementary Data 3 from Merkel Cell Polyomavirus Infection, Large T Antigen, Retinoblastoma Protein and Outcome in Merkel Cell ...
Virve Koljonen (3879877), Heli Kukko (14983385), Tom Böhling (92476), Harri Sihto (3627110), Risto Sankila (14983388), Heikki Joensuu (43841)   +5 more
core   +1 more source

Tumor Immunotherapy and Microbiome: From Bench‐to‐Bedside Applications

MedComm, Volume 7, Issue 2, February 2026.
The microbiome is related to the efficacy of immunotherapy and can be utilized to predict the efficacy and adverse reactions of immunotherapy. Microbiome‐targeted intervention strategies can improve the efficacy of ICI, but necessitating more comprehensive exploration.
Anqi Lin, Minying Xiong, Aimin Jiang, Li Chen, Lihaoyun Huang, Kailai Li, Hank Z. H. Wong, Jian Zhang, Zaoqu Liu, Quan Cheng, Bufu Tang, Pengpeng Zhang, Peng Luo   +12 more
wiley   +1 more source

Detection of Merkel Cell Carcinoma Polyomavirus in Mucosal Merkel Cell Carcinoma

International Journal of Surgical Pathology, 2010
A 61-year-old woman presented with solitary lymphadenopathy suspicious for lymphoma. An excisional biopsy of a right inguinal lymph node demonstrated metastatic Merkel cell carcinoma (MCC). No skin lesions were detected, but a primary nasopharyngeal mass was identified. A microscopic examination of the nasopharyngeal tumor and the lymph node metastasis
Karen N, Wu, Peter A, McCue, Adam, Berger, Joseph R, Spiegel, Zi-Xuan, Wang, Agnieszka K, Witkiewicz   +5 more
openaire   +3 more sources

Supplementary Data 2 from Merkel Cell Polyomavirus Infection, Large T Antigen, Retinoblastoma Protein and Outcome in Merkel Cell Carcinoma

, 2011
Supplementary Data 2 from Merkel Cell Polyomavirus Infection, Large T Antigen, Retinoblastoma Protein and Outcome in Merkel Cell ...
Virve Koljonen (3879877), Heli Kukko (14983385), Tom Böhling (92476), Harri Sihto (3627110), Risto Sankila (14983388), Heikki Joensuu (43841)   +5 more
core   +1 more source