Results 81 to 90 of about 5,177 (192)
Journal of Skin Cancer, Volume 2026, Issue 1, 2026.Aim/Objectives Merkel cell carcinoma (MCC) is a rare, aggressive neuroendocrine skin cancer with a poorly understood etiology and lacking high‐level evidence to guide its management. This study examined the presentation and outcome related to MCC treatment at a Canadian center.
Megan McDonald +5 more
wiley +1 more source
Merkel Cell Carcinoma: Evolving Therapeutics, Continued Challenges
Head &Neck, Volume 47, Issue 12, Page 3414-3428, December 2025.ABSTRACT Background Merkel Cell Carcinoma (MCC) is a rare, aggressive neuroendocrine malignancy with rising incidence, influenced by ultraviolet (UV) radiation and Merkel cell polyomavirus (MCPyV). Methods This review summarizes recent advances in MCC management, based on an analysis of current literature, focusing on immune checkpoint inhibitors (ICIs)
Hunter A. Holley +6 more
wiley +1 more source
JEADV Clinical Practice, Volume 4, Issue 5, Page 1101-1113, December 2025.Cutaneous squamous cell carcinoma (cSCC) exhibits a pro‐tumorigenic immune environment, increased oncologic signalling, and tumour remodelling, with three immune subgroups from ‘cold’ to ‘hot’. Organ transplant recipients (OTR) with cSCC showed reduced T‐cells and greater viral enrichment, especially HPV, and a higher disease burden.
Choon Chiat Oh +8 more
wiley +1 more source
, 2011 Supplementary Data 1 from Merkel Cell Polyomavirus Infection, Large T Antigen, Retinoblastoma Protein and Outcome in Merkel Cell ...
Virve Koljonen (3879877) +5 more
core +1 more source
Molecular Oncology, Volume 19, Issue 11, Page 3035-3059, November 2025.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
, 2011 Supplementary Data 2 from Merkel Cell Polyomavirus Infection, Large T Antigen, Retinoblastoma Protein and Outcome in Merkel Cell ...
Virve Koljonen (3879877) +5 more
core +1 more source
The Human Polyomavirus Middle and Alternative T-Antigens; Thoughts on Roles and Relevance to Cancer
Frontiers in Microbiology, 2018 Approximately 15–20% of human cancer is related to infection, which renders them potentially preventable by antimicrobial or antiviral therapy. Human polyomaviruses (PyVs) are relevant in this regard, as illustrated by the involvement of Merkel cell ...
Els van der Meijden, Mariet Feltkamp
doaj +1 more source
The Epidemiology of Neuroendocrine Carcinomas in Taiwan: A Population‐Based Cancer Registry Study
Cancer Medicine, Volume 14, Issue 21, November 2025.Differences in the incidence trends and clinical outcomes of NECs suggest different etiologies and heterogeneities of NECs. Further investigations on risk factor identification and novel treatment strategies for NECs are warranted. ABSTRACT Background Lung and small cell neuroendocrine carcinomas (SCCs) are the most common sites and histological types ...
Yi‐Hsin Yang +5 more
wiley +1 more source
, 2011 Supplementary Data 3 from Merkel Cell Polyomavirus Infection, Large T Antigen, Retinoblastoma Protein and Outcome in Merkel Cell ...
Virve Koljonen (3879877) +5 more
core +1 more source
The Journal of Dermatology, Volume 52, Issue 11, Page e954-e967, November 2025.ABSTRACT Merkel cell carcinoma (MCC) is a highly malignant skin cancer characterized by high rates of recurrence and metastasis. Although rare, the incidence has noticeably increased in recent years. It is also known to be a highly immunogenic tumor, and the use of immune checkpoint inhibitors has begun for advanced cases.
Motoki Nakamura +11 more
wiley +1 more source