Viral hijacking of cellular metabolism. [PDF]
, 2019 This review discusses the current state of the viral metabolism field and gaps in knowledge that will be important for future studies to investigate.
Ch'ng, James +2 more
core
The DNA damage response promotes Polyomavirus JC infection by nucleus to cytoplasm NF-Kappa B activation. [PDF]
, 2017 Background: Infection of glial cells by human neurotropic polyomavirus JC (JCV), the causative agent of the CNS demyelinating disease progressive multifocal leukoencephalopathy (PML), rapidly inflicts damage to cellular DNA.
Bellizzi, Anna +6 more
core +1 more source
Merkel cell carcinoma: a population-based study on mortality and the association with other cancers [PDF]
, 2011 Few population-based epidemiological data are available on Merkel cell carcinoma (MCC), a rare lethal non-melanoma skin cancer. We analysed multiple-cause-of-death records to describe MCC mortality and trends and the association with other primary ...
Valeria Ascoli +4 more
core +1 more source
The Journal of Dermatology, Volume 52, Issue 11, Page e954-e967, November 2025.ABSTRACT Merkel cell carcinoma (MCC) is a highly malignant skin cancer characterized by high rates of recurrence and metastasis. Although rare, the incidence has noticeably increased in recent years. It is also known to be a highly immunogenic tumor, and the use of immune checkpoint inhibitors has begun for advanced cases.
Motoki Nakamura +11 more
wiley +1 more source
Detection of Merkel Cell Carcinoma Polyomavirus in Mucosal Merkel Cell Carcinoma
International Journal of Surgical Pathology, 2010 A 61-year-old woman presented with solitary lymphadenopathy suspicious for lymphoma. An excisional biopsy of a right inguinal lymph node demonstrated metastatic Merkel cell carcinoma (MCC). No skin lesions were detected, but a primary nasopharyngeal mass was identified.
Karen N, Wu +5 more
openaire +3 more sources
A review of the epidemiology and treatment of Merkel cell carcinoma
Clinics, 2011 Merkel cell carcinoma is a very rare and aggressive neoplasm. Due to its rarity, therapeutic guidelines are not well established, especially for regionally advanced disease.
João Pedreira Duprat +3 more
doaj +1 more source
Rak neuroendokrynny skóry (Merkla) – aktualne poglądy na patogenezę oraz metody leczenia
Przegląd Dermatologiczny, 2011 Merkel cell carcinoma (MCC) is a rare, aggressive neuroendocrine skincancer localized mostly on exposed, sun-damaged skin – on the headand neck. Although rapidly increasing incidence of MCC is observed,the pathogenesis of the tumour is unclear. Diagnosis
Beata Sosada, Ligia Brzezińska-Wcisło
doaj
Preclinical evaluation of NF-kappa B-triggered dendritic cells expressing the viral oncogenic driver of Merkel cell carcinoma for therapeutic vaccination [PDF]
, 2017 Background: Merkel cell carcinoma (MCC) is a rare but very aggressive skin tumor that develops after integration of a truncated form of the large T-antigen (truncLT) of the Merkel cell polyomavirus (MCV) into the host’s genome.
Doerrie, Jan +10 more
core +2 more sources
PLoS Pathogens, 2010 The Polyomaviridae constitute a family of small DNA viruses infecting a variety of hosts. In humans, polyomaviruses can cause infections of the central nervous system, urinary tract, skin, and possibly the respiratory tract.
Els van der Meijden +5 more
doaj +1 more source
Merkel cell polyomavirus: molecular insights into the most recently discovered human tumour virus. [PDF]
, 2014 A fifth of worldwide cancer cases have an infectious origin, with viral infection being the foremost. One such cancer is Merkel cell carcinoma (MCC), a rare but aggressive skin malignancy.
Abdul-Sada, H +7 more
core +3 more sources