Results 101 to 110 of about 4,878,012 (192)

In vitro and in vivo characterization of the cytomegalovirus and polyomavirus BK specific immune response [PDF]

, 2008
During my PhD thesis several aspects of the interaction of Cytomegalovirus and Polyomavirus BK with the host’s immune system were examined (see list of publications).
Egli, Adrian
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Updates in the Management of Merkel Cell Carcinoma

Brazilian Journal of Oncology, 2019
Merkel cell carcinomas are rare cutaneous malignancies with neuroendocrine features that affect elderly individuals with a history of chronic sun exposure and immunosuppression.
Paulo Henrique do Amor Divino, Gabriel Passos Souza, Maurício Fernando Silva-Almeida Ribeiro, George Horta, Fabíola Ambrosio Silveira-Lima, Alessandra Corte Real-Salgues, Rodrigo Ramella Munhoz   +6 more
doaj   +1 more source

A molecular case-control study of the Merkel cell polyomavirus in colon cancer.

, 2011
To explore the putative role of the Merkel cell polyomavirus in human colon cancer, a prospective molecular case-control study was undertaken in patients and their relatives enrolled during a screening program. Fresh tissue samples from 64 cases of colon
D'AGARO, PIERLANFRANCO, Minicozzi, Anna, CAMPELLO, CESARE, MINICOZZI, Annamaria, Comar M, POLI, Albino, RODELLA, LUCA, Poli A., Micozzi A, COMAR, Manola, Albino Poli, Cesare Campello, Manola Comar, D'Agaro P, Rondella L, Anna Minicozzi, Luca Rodella, Pierlanfranco D'Agaro   +17 more
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Unmasking hidden Merkel cell carcinoma recurrences: Three illustrative cases of patients with rising viral oncoprotein antibody levels and challenge of requiring multi-modal imaging to detect clinical disease

Radiology Case Reports
Merkel cell carcinoma (MCC) is a neuroendocrine skin cancer with a high risk of recurrence and metastasis. Regular surveillance through physical exams and imaging studies is crucial for the timely detection of recurrences.
Nora A. Alexander, BS, Paul Nghiem, MD, PhD, Delphine L. Chen, MD, Song Y. Park, MD   +3 more
doaj   +1 more source

Merkel Cell Polyomavirus—Pathophysiology and Treatment in the Era of Gene-Targeted Therapies

Merkel cell polyomavirus (MCPyV) is a significant contributor to the development of Merkel cell carcinoma (MCC), an aggressive skin cancer with high recurrence and a low survival rate. In fact, it is the deadliest skin cancer.
McMillan, Nigel AJ, Chokwassanasakulkit, Trairong   +1 more
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Large T and small T antigens of Merkel cell polyomavirus

, 2015
Merkel cell polyomavirus (MCV) is the etiological agent of Merkel cell carcinoma (MCC), a rare and highly lethal human skin cancer. A natural component of skin flora, MCV becomes tumorigenic only after integration into the host DNA together with specific
Moore, Patrick S., Chang, Yuan, Wendzicki, Justin A.   +2 more
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Delta-catenin is required for cell proliferation in virus-positive Merkel cell carcinoma cell lines but not in human fibroblasts

mBio
Merkel cell carcinoma (MCC) is a highly aggressive neuroendocrine skin cancer often driven by the integration of Merkel cell polyomavirus (MCPyV) into the host genome and the persistent expression of its viral oncoproteins, small tumor (ST) antigen, and ...
Joselyn Landazuri Vinueza, Nicholas J. H. Salisbury, Kristine N. Dye, Ann Roman, Denise A. Galloway   +4 more
doaj   +1 more source

Phosphorylation of Large T Antigen Regulates Merkel Cell Polyomavirus Replication

, 2014
Merkel Cell Polyomavirus (MCPyV) was recently discovered as a novel human polyomavirus that is associated with ~80% of Merkel Cell Carcinomas.
Xin Wang, Jianxin You, Sabrina Tsang, Jason Diaz, Jing Jiao   +4 more
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Tumor virus–induced lineage survival circuit drives Merkel cell carcinogenesis

The Journal of Clinical Investigation
Approximately 80% of Merkel cell carcinoma (MCC) cases are caused by Merkel cell polyomavirus (MCV), driven by its T antigen oncogene. Why MCV drives MCC, a skin cancer that displays the neuroendocrine Merkel cell phenotype, remains unclear.
Masahiro Shuda
doaj   +1 more source

PathBeat. Number 14 (Winter 2013) University of Iowa Department of Pathology. [PDF]

, 2013
University of Iowa Department of Pathology ...

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