Results 111 to 120 of about 7,231 (207)

Remembering the forgotten child: the role of immune checkpoint inhibition in patients with human immunod eficiency virus and cancer. [PDF]

, 2019
Patients with human immunodeficiency virus (HIV) infection have a high risk of developing virally-mediated cancers. These tumors have several features that could make them vulnerable to immune checkpoint inhibitors (ICIs) including, but not limited to ...
Adashek, Jacob J, Galanina, Natalie, Junior, Pedro Nazareth Aguiar, Kurzrock, Razelle   +3 more
core  

Multiplex detection in tonsillar tissue of all known human polyomaviruses [PDF]

, 2017
Background: In the past few years, eleven new human viruses have joined the two previously known members JCPyV and BKPyV of the Polyomaviridae family, by virtue of molecular methods. Serology data suggest that infections with human polyomaviruses (HPyVs)
Aaltonen, Leena-Maija, Hedman, Klaus, Pyöriä, Lari, Ramqvist, Torbjorn, Sadeghi, Mohammadreza, Soderlund-Venermo, Maria, Toppinen, Mari, Wang, Yilin   +7 more
core   +1 more source

Merkel Cell Polyomavirus and Cutaneous Merkel Cell Carcinoma [PDF]

Future Science OA, 2016
Minutilli, Ettore, Mulè, Antonino
openaire   +2 more sources

Unmasking hidden Merkel cell carcinoma recurrences: Three illustrative cases of patients with rising viral oncoprotein antibody levels and challenge of requiring multi-modal imaging to detect clinical disease

Radiology Case Reports
Merkel cell carcinoma (MCC) is a neuroendocrine skin cancer with a high risk of recurrence and metastasis. Regular surveillance through physical exams and imaging studies is crucial for the timely detection of recurrences.
Nora A. Alexander, BS, Paul Nghiem, MD, PhD, Delphine L. Chen, MD, Song Y. Park, MD   +3 more
doaj   +1 more source

Updates in the Management of Merkel Cell Carcinoma

Brazilian Journal of Oncology, 2019
Merkel cell carcinomas are rare cutaneous malignancies with neuroendocrine features that affect elderly individuals with a history of chronic sun exposure and immunosuppression.
Paulo Henrique do Amor Divino, Gabriel Passos Souza, Maurício Fernando Silva-Almeida Ribeiro, George Horta, Fabíola Ambrosio Silveira-Lima, Alessandra Corte Real-Salgues, Rodrigo Ramella Munhoz   +6 more
doaj   +1 more source

Detection of Malawi polyomavirus sequences in secondary lymphoid tissues from Italian healthy children: a transient site of infection [PDF]

, 2016
BACKGROUND: The novel Malawi polyomavirus (MWPyV) was initially detected in stool specimens from healthy children and children with gastrointestinal symptoms, mostly diarrhea, indicating that MWPyV might play a role in human gastroenteric diseases ...
Comar, M, Knowles, A, Orzan, E, Papa, N, Zanotta, N   +4 more
core   +2 more sources

Clinical metagenomics. [PDF]

, 2019
Clinical metagenomic next-generation sequencing (mNGS), the comprehensive analysis of microbial and host genetic material (DNA and RNA) in samples from patients, is rapidly moving from research to clinical laboratories. This emerging approach is changing
Chiu, Charles Y, Miller, Steven A
core  

Mucin Biopolymers As Broad-Spectrum Antiviral Agents [PDF]

, 2012
Mucus is a porous biopolymer matrix that coats all wet epithelia in the human body and serves as the first line of defense against many pathogenic bacteria and viruses.
Bergey E. J., Bergey E. J., Blixtjohansen G., Bloom J. D., Buck C. B., Buck C. B., Buck C. B., Celli J., Celli J. P., Chang Y., Chittum H. S., Christopher B. Buck, Cone R. A., Corinna Lieleg, Crater J. S., Day P. M., Duxbury A. J., Garcea R. L., Jesse Bloom, Kalluri R., Katharina Ribbeck, Lai S. K., Lai S. K., Lai S. K., Lieleg O., Lieleg O., Linden S. K., Loyo M., Mahalingam A., Mall A. S., Mall A. S., Matrosovich M. N., Matsui H., McGuckin M. A., Neumann G., Oliver Lieleg, Olmsted S. S., Pastrana D. V., Raynal B. D., Reid A. H., Roy A. M. M., Saltzman W. M., Schiffman M., Schiller J. T., Schilling J., Thornton D. J., Tian P., Varghese J. N., Wieland U., Yates J. R., Yolken R. H.   +50 more
core   +1 more source

Delta-catenin is required for cell proliferation in virus-positive Merkel cell carcinoma cell lines but not in human fibroblasts

mBio
Merkel cell carcinoma (MCC) is a highly aggressive neuroendocrine skin cancer often driven by the integration of Merkel cell polyomavirus (MCPyV) into the host genome and the persistent expression of its viral oncoproteins, small tumor (ST) antigen, and ...
Joselyn Landazuri Vinueza, Nicholas J. H. Salisbury, Kristine N. Dye, Ann Roman, Denise A. Galloway   +4 more
doaj   +1 more source

Latest update on the clinical features and management of Merkel cell carcinoma [PDF]

, 2012
Merkel cell carcinoma (MCC), is a rare, highly malignant skin tumour, with a poor prognosis. Though the aetiology of MCC is not known, but there are several features that it shares with melanoma.
Abbasi, Ahmed Nadeem, Zahid, Sumaiya
core   +1 more source