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Merkel cell carcinoma in an immunosuppressed patient [PDF]

Anais Brasileiros de Dermatologia, 2017
Merkel cell carcinoma is an uncommon neuroendocrine carcinoma with a rising incidence and an aggressive behavior. It predominantly occurs in older patients, with onset occurring at a mean age of 75-80 years.
Heliana Freitas de Oliveira Góes, Caren dos Santos Lima, Maria Cláudia de Almeida Issa, Flávio Barbosa Luz, Luciana Pantaleão, José Gabriel Miranda da Paixão   +5 more
doaj   +2 more sources

Multiple gastrointestinal metastases of Merkel cell carcinoma [PDF]

Medicina, 2016
Merkel cell carcinoma is an aggressive skin malignancy. Primary Merkel cell carcinomas are treated by wide radical excision with or without adjuvant radiotherapy, while benefits of adjuvant chemotherapy remain doubtful.
Eligijus Poškus, Gediminas Platkevičius, Vilma Simanskaitė, Ernesta Rimkevičiūtė, Marius Petrulionis, Kestutis Strupas   +5 more
doaj   +2 more sources

Lanreotide, a Somatostatin Analogue, in Advanced Merkel Cell Carcinoma: A Prospective Single-Arm Phase II Study. [PDF]

Cancer Med
ABSTRACT Background Merkel Cell Carcinoma (MCC) is a rare, aggressive neuroendocrine and epithelial skin cancer. Somatostatin analogues, such as lanreotide, have shown efficacy in managing other neuroendocrine tumors. Retrospective studies suggest that lanreotide may induce partial response or disease stabilization in patients with advanced MCC.
Charles J, Belbezier A, Mouret S, Dreno B, Dalle S, Lebbe C, Hainaut-Wierzbicka E, Stefan A, de Quatrebarbes J, Dereure O, Zehou O, Mansard S, Dupuy A, Dutriaux C, Grange F, Gaudy-Marqueste C, Montaudié H, Arnault JP, Le Corre Y, Kervarrec T, Quesada JL, Samimi M, Leccia MT, Group of Cutaneous Oncology of the French Society of Dermatology.   +23 more
europepmc   +2 more sources

Merkel Cell Carcinoma With Divergent Differentiation-Or Something Else? A Triphasic Cutaneous Carcinoma With Lineage Plasticity. [PDF]

J Cutan Pathol
ABSTRACT Merkel cell carcinoma (MCC) is a rare, aggressive cutaneous neuroendocrine carcinoma that typically arises in sun‐exposed skin of older or immunosuppressed patients. Combined or collision tumors involving MCC and other cutaneous malignancies are uncommon, and tumors exhibiting more than two distinct malignant phenotypes are exceptionally rare.
Khalil Z, Elameen H, Alomari AK.
europepmc   +2 more sources

Contemporary Literature Review of Clinical Characteristics and Management of Merkel Cell Carcinoma [PDF]

Liaquat National Journal of Cancer Care, 2022
Merkel cell carcinoma is a rare aggressive, non-melanomatous cutaneous malignancy with rising incidence. It has two distinct etiologies Merkel cell polyomavirus associated and non-associated, usually presents as painless, indurated, solitary violaceous
Laraib Khan, Ahmed Nadeem Abbasi, Sohail Rasool, Calogero Casà, Andrea D’Aviero   +4 more
doaj   +1 more source

Treatment and Outcome of Merkel Cell Carcinoma in A Single Center

Zhongliu Fangzhi Yanjiu, 2023
Objective To investigate the clinical features, treatment, and outcome characteristics of patients with Merkel cell carcinoma. Methods The clinical manifestations, laboratory tests, diagnosis and treatment, and follow-up data of six patients with Merkel ...
REN Mengwei, XUE Xuemin, LIU Peng
doaj   +1 more source

Merkel cell carcinoma appearing 9 years after kidney transplantati-on

Liječnički vjesnik, 2023
Merkel cell carcinoma (MCC) is a rare, highly aggressive skin cancer with neuroendocrine features. Immunosuppressants that are administered after transplantation can increase the risk of Merkel cell carcinoma.
Tomislav Brajković, Krunoslav Budimir, Stjepan Skok, Bojana Maksimović   +3 more
doaj   +1 more source

Merkel cell carcinoma: epidemiology, clinical features, diagnosis and treatment of a rare disease

Anais Brasileiros de Dermatologia, 2023
Merkel cell carcinoma is a rare skin cancer with neuroendocrine differentiation. The risk factors include sun exposure, advanced age, immunosuppression (such as transplant recipients, patients with lymphoproliferative neoplasms, or patients with HIV ...
Stella Meireles Siqueira, Gabriella Campos-do-Carmo, Alexssandra Lima Siqueira dos Santos, Cícero Martins, Andreia Cristina de Melo   +4 more
doaj   +1 more source

A clinical case of Merkel cell carcinoma

Сибирский научный медицинский журнал, 2023
Merkel cell carcinoma is a rare, rapidly progressive, aggressive skin tumor with frequent metastasis and high mortality. The disease is a multifactorial pathology resulting from the interaction of endogenous and exogenous risk factors.
R. V. Saranyuk, T. A. Gosteva, E. D. Tsnobiladze   +2 more
doaj   +1 more source

Perforated gastric metastasis of Merkel cell carcinoma: Case report and review of the literature

Human Pathology: Case Reports, 2017
A 53 year-old Vietnamese male presented with a complaint of a left buttock mass which had grown to 8.0 cm during the past three years. A CT scan revealed the gluteal lesion and a large mass of the stomach.
Darshan Trivedi, MD, PhD, Victoria Collins, MD, Evans Roberts, MD, John Scopetta, MD, Tong Wu, MD, PhD, Byron Crawford, MD, Yukihiro Nakanishi, MD, PhD   +6 more
doaj   +1 more source