Results 11 to 20 of about 13,982 (210)
Biomedicines, 2021 Merkel cell carcinoma (MCC) is a rare and extremely aggressive neuroendocrine carcinoma of the skin, with increasing incidence worldwide. This review intends to propose a comprehensive evaluation of MCC epidemiology, clinical features, pathogenetic ...
Elena Dellambra +10 more
doaj +11 more sources
Bezmiâlem Science, 2023 Merkel cell carcinoma (MCC) is a rare tumor that arises from mechanoreceptor Merkel cells. Ultraviolet exposure, immunosuppression and Merkel cell polyoma virus play a significant role in tumor pathogenesis. Although it typically presents as an initially
Selma SÖNMEZ ERGÜN +5 more
doaj +4 more sources
Surgical Pathology Clinics, 2017 Merkel cell carcinoma (MCC) encompasses neuroendocrine carcinomas primary to skin and occurs most commonly in association with clonally integrated Merkel cell polyomavirus with related retinoblastoma protein sequestration or in association with UV radiation-induced alterations involving the TP53 gene and mutations, heterozygous deletion, and ...
Becker, Jürgen +6 more
semanticscholar +11 more sources
Merkel Cell Polyomavirus and Merkel Cell Carcinoma [PDF]
Cancers, 2020 Viruses are the cause of approximately 15% of all human cancers. Both RNA and DNA human tumor viruses have been identified, with Merkel cell polyomavirus being the most recent one to be linked to cancer. This virus is associated with about 80% of Merkel cell carcinomas, a rare, but aggressive cutaneous malignancy.
Valeria Pietropaolo +2 more
openaire +5 more sources
Tidsskrift for Den norske legeforening, 2022 Merkel cell carcinoma is an uncommon but aggressive tumour with a high metastatic potential. A rapidly growing, non-tender cutaneous tumour on sun-exposed areas of the body in older patients should raise suspicion of the condition. It may be necessary to combine the patient history with clinical, radiological and pathological findings in order to make ...
Morten Kristoffer, Nyrud +6 more
openaire +3 more sources
Merkel cell polyomavirus and associated Merkel cell carcinoma
Tumour Virus Research, 2022 Merkel cell polyomavirus (MCPyV) is a ubiquitous skin infection that can cause Merkel cell carcinoma (MCC), a highly lethal form of skin cancer with a nearly 50% mortality rate.
June F. Yang, Jianxin You
doaj +2 more sources
Merkel cell polyomavirus and Merkel cell carcinoma [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2017 Merkel cell polyomavirus (MCPyV) causes the highly aggressive and relatively rare skin cancer known as Merkel cell carcinoma (MCC). MCPyV also causes a lifelong yet relatively innocuous infection and is one of 14 distinct human polyomaviruses species.
James A Decaprio
exaly +3 more sources
World Journal of Surgical Oncology, 2006 Background Merkel cell carcinoma (MCC) is an unusual primary neuroendocrine carcinoma of the skin. MCC is a fatal disease, and patients have a poor chance of survival.
Koljonen Virve
doaj +3 more sources
Prevalence of Merkel cell polyomavirus in Merkel cell carcinoma [PDF]
Modern Pathology, 2009 It has recently been shown that Merkel cell carcinoma, a rare and often lethal cutaneous malignancy, frequently harbors a novel clonally integrated polyomavirus aptly named Merkel cell polyomavirus. We aimed to study the prevalence of Merkel cell polyomavirus in cases of Merkel cell carcinoma, using specimens from formalin-fixed, paraffin-embedded ...
Eric J Duncavage +2 more
exaly +3 more sources
New England Journal of Medicine, 2019 In XXI century Merkel cell carcinoma (MCC) is a still very rare form of the skin cancer with an aggressive behavior. We present a case of 77-year-old female patient with a tumor with bluish skin, approx. 2 cm diameter, hard texture palpation of the right zygomatic area of the face. There were no enlarged lymph nodes in the head or neck.
Pedro J. Gomez-Arias +1 more
+11 more sources