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Merkel cell carcinoma (MCC) is a rare and extremely aggressive neuroendocrine carcinoma of the skin, with increasing incidence worldwide. This review intends to propose a comprehensive evaluation of MCC epidemiology, clinical features, pathogenetic ...
Elena Dellambra +10 more
doaj +13 more sources
Merkel Cell Polyomavirus and Merkel Cell Carcinoma [PDF]
Viruses are the cause of approximately 15% of all human cancers. Both RNA and DNA human tumor viruses have been identified, with Merkel cell polyomavirus being the most recent one to be linked to cancer. This virus is associated with about 80% of Merkel cell carcinomas, a rare, but aggressive cutaneous malignancy.
Valeria Pietropaolo +2 more
core +8 more sources
Histological, Immunohistological, and Clinical Features of Merkel Cell Carcinoma in Correlation to Merkel Cell Polyomavirus Status [PDF]
Merkel cell carcinoma is a rare, but highly malignant tumor of the skin with high rates of metastasis and poor survival. Its incidence rate rises and is currently about 0.6/100000/year.
T. Jaeger, J. Ring, C. Andres
doaj +3 more sources
AbstractPurpose: To determine the natural history and treatment outcomes for patients with Merkel cell carcinoma.Methods: Review of the literature.Results: The probability of regional node involvement at presentation exceeds 50%; few patients present with distant metastases.
William M, Mendenhall +2 more
core +5 more sources
The guidelines outline the clinical, pathological, and dermoscopic features of cutaneous squamous cell carcinoma and Merkel cell carcinoma, along with the recommended diagnostic and therapeutic procedures.
Aleksandra Lesiak +21 more
doaj +2 more sources
Merkel cell carcinoma of the abdominal wall
Merkel cell carcinoma also known as neuroendocrine carcinoma of the skin is a very rare skin tumor. It commonly presents in the old age and the common sites are head, neck and extremities.
Vandana L Gaopande +3 more
doaj +2 more sources
Merkel cell carcinoma (MCC) is a neuroendocrine carcinoma that typically presents as a rapidly enlarging violaceous papulonodule on sun-damaged skin in elderly patients. MCC has high rates of local recurrence, metastasis, and poor survival. Treatment of the primary tumor involves surgical excision with possible adjuvant radiation therapy, whereas ...
Daniel J, Lewis +9 more
openaire +3 more sources
Background Merkel cell carcinoma (MCC) is an unusual primary neuroendocrine carcinoma of the skin. MCC is a fatal disease, and patients have a poor chance of survival.
Koljonen Virve
doaj +3 more sources
Merkel cell carcinoma (MCC) encompasses neuroendocrine carcinomas primary to skin and occurs most commonly in association with clonally integrated Merkel cell polyomavirus with related retinoblastoma protein sequestration or in association with UV radiation-induced alterations involving the TP53 gene and mutations, heterozygous deletion, and ...
Ramya, Vangipuram, Stephen K, Tyring
+11 more sources
In XXI century Merkel cell carcinoma (MCC) is a still very rare form of the skin cancer with an aggressive behavior. We present a case of 77-year-old female patient with a tumor with bluish skin, approx. 2 cm diameter, hard texture palpation of the right zygomatic area of the face. There were no enlarged lymph nodes in the head or neck.
Pedro J. Gomez-Arias +1 more
+11 more sources

