Results 41 to 50 of about 13,262 (168)
American Journal of Clinical Oncology, 2013 Merkel cell carcinoma (MCC) is a rare, clinically aggressive cutaneous neuroendocrine neoplasm with a high mortality rate. Though the etiology is not precisely known, Merkel cell polyomavirus DNA has been found recently in a large percentage of MCC tumors.
Emma, Ramahi +3 more
openaire +2 more sources
The Journal of Dermatology, EarlyView.ABSTRACT Immune checkpoint inhibitor (ICI)‐driven alterations in the immune system can induce immune‐related adverse events (irAEs). Cutaneous irAEs are notable for being the most common and for their early onset; however, the risk factors underlying their development and severity remain unclear. In this study, we retrospectively analyzed 1224 Japanese
Tomoya Watanabe +4 more
wiley +1 more source
Merkel Cell Carcinoma: Interdisciplinary Management of a Rare Disease
Journal of Skin Cancer, 2013 Background. The goal of this paper is to review contemporary multidisciplinary treatment with reference to Merkel cell carcinoma. Management of this rare but highly aggressive skin cancer is a complex undertaking that necessitates an understanding of its
Sven Schneider +2 more
doaj +1 more source
Merkel cell polyomavirus and associated Merkel cell carcinoma
Tumour Virus Research, 2022 Merkel cell polyomavirus (MCPyV) is a ubiquitous skin infection that can cause Merkel cell carcinoma (MCC), a highly lethal form of skin cancer with a nearly 50% mortality rate.
June F. Yang, Jianxin You
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Advances in γδ T Cells: Cutaneous Biology and Therapeutic Potential for Skin Neoplasms
The Journal of Dermatology, EarlyView.ABSTRACT γδ T cells represent an increasingly important subset of T lymphocytes in the immune response to cancer and as a platform for novel immunotherapies. The aim of this review is to synthesize recent insights into the biology and advances in therapeutic applications of γδ T cells in cutaneous malignancies, especially melanoma, within a framework ...
Simo Du +9 more
wiley +1 more source
Acta Dermato-VenereologicaMerkel cell carcinoma is a rare, aggressive skin cancer in which Merkel cell polyoma virus (MCPyV) is frequently pathogenically involved. After failure of anti-programmed cell death protein 1/programmed cell death ligand 1 immunotherapy, therapeutic ...
Ferdinand Toberer +8 more
doaj +1 more source
Merkel cell carcinoma with seborrheic keratosis: A unique association
Indian Journal of Pathology and Microbiology, 2018 Merkel cell carcinoma (MCC) is a rare, clinically aggressive neuroendocrine carcinoma of the skin; MCC is 40 times less common as compared to melanoma. The most frequently reported sites have been the head and neck, extremities, and trunk.
Murthy S Anand +3 more
doaj +1 more source
ANZ Journal of Surgery, EarlyView.ABSTRACT Background Merkel cell carcinoma (MCC) is a rare, aggressive cutaneous neuroendocrine malignancy with a high risk of nodal metastasis. Sentinel lymph node biopsy (SLNB) is used to stage clinically node‐negative disease and to guide adjuvant therapy decisions.
Julie Ahn +2 more
wiley +1 more source
Archives of Pathology and Laboratory Medicine, 2010 Abstract Merkel cell carcinoma is a rare, highly aggressive neuroendocrine cutaneous neoplasm with a variable clinical presentation. Histologically, it is a predominantly dermal-based lesion composed of monotonous small round cells with scanty cytoplasm, often difficult to differentiate from small round cell tumors, metastatic small ...
Hannah H, Wong, Jun, Wang
openaire +4 more sources
Secondary Merkel Cell Carcinoma Manifested in the Parotid
Case Reports in Dermatological Medicine, 2013 Background. Merkel cell carcinoma of the head and neck is a rare and aggressive malignant tumour. Both the dermatological and surgical colleagues should be aware of this entity as lesions usually present on sun exposed areas of the skin such as the head ...
M. Basati, K. Kassam, A. Messiha
doaj +1 more source