Results 41 to 50 of about 5,234,907 (203)

Neuroendocrine (Merkel cell) carcinoma of the auricle [PDF]

open access: yesArchive of Oncology, 2004
Merkel cell carcinoma is a rare locally aggressive malignancy. Most commonly occurs in the head and neck area and only six cases on the auricle have been reported.
Divani Smaroula   +5 more
doaj   +1 more source

Replication Data for: Secretomic analysis of extracellular vesicles originating from polyomavirus-negative and polyomavirus-positive Merkel cell carcinoma cell lines

open access: yes, 2019
This dataset is about analyses of two Merkel cell polyomavirus (MCPyV)-negative and two MCPyV–positive Merkel cell lines secretomic proteins.Abstract: Extracellular vesicles or exosomes constitute an evolutionarily conserved mechanism of intercellular ...
Konstantinell, Aelita Gloria Virginia
core   +1 more source

Merkel Cell Carcinoma of the Mandible: A Case of Spontaneous Acceleration of the Growth

open access: yesReports, 2019
A 78 year old Caucasian woman, was admitted to the hospital for evaluation of a mass to the anterior surface of the left mandibular angle and left submandibular area present for the past year with rapid acceleration of growth over three weeks prior to ...
Mansoor Choudhry   +5 more
doaj   +1 more source

MERKEL CELL CARCINOMA – PRO AND CONS ASPECTS FOR SENTINEL LYMPH NODE BIOPSY [PDF]

open access: yesRomanian Medical Journal, 2019
Merkel cell carcinoma represents an aggressive histopathological subtype of skin cancer with a high propensity to spread via lymphatic route. Once the benefits of the sentinel lymph node detection have been proven in malignant melanoma, the effectiveness
Nicolae Bacalbasa   +4 more
doaj   +1 more source

Complete Pathway Refactoring and Combinatorial Biosynthesis of Anthracyclines for Modulation of Histone Eviction and DNA Damage Bioactivities

open access: yesAngewandte Chemie International Edition, EarlyView.
A synthetic biology platform was established for the complete refactoring of complex anthracycline biosynthetic pathways in Streptomyces coelicolor using standardized, chemically synthetic DNA parts. This modular construction enabled streamlined combinatorial biosynthesis, yielding novel analogs that decouple DNA damage from chromatin damage (histone ...
Rongbin Wang   +15 more
wiley   +1 more source

Vulvar neuroendocrine carcinoma that is independent of merkel cell polyomavirus and human papillomavirus suggests endometrial cancer recurrence: a case report

open access: yesBMC Endocrine Disorders, 2022
Background Vulvar neuroendocrine carcinomas with small cell morphology need an appropriate differential diagnosis with respect to primary Merkel cell carcinomas, primary small cell neuroendocrine carcinomas, and secondary/metastatic carcinomas.
Tomoko Hirakawa   +4 more
doaj   +1 more source

Regulatory harmonization: Evolution, globalization and future directions

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm   +2 more
wiley   +1 more source

Prognostic significance of tumour budding in Merkel cell carcinoma

open access: yes, 2023
Prognostic factors in Merkel cell carcinoma (MCC) are scarce. Tumour budding (TB) has been shown to have a prognostic role in different cancers but has not been explored in MCC. We aimed to determine if TB influences survival in MCC.
Luisa F Rivera-Moncada   +2 more
core   +1 more source

Concomitant chronic lymphocytic leukemia and Merkel cell carcinoma

open access: yesDermatologica Sinica, 2015
We present the case of a 69-year-old Caucasian man with a 5-year history of untreated chronic lymphocytic leukemia who presented with Merkel cell carcinoma on the right gluteal region.
Darko Antic   +5 more
doaj   +1 more source

Treatment Patterns and Survival Outcomes of Head and Neck Merkel Cell Carcinoma: An Age‐Stratified Analysis

open access: yesHead &Neck, EarlyView.
ABSTRACT Background H&N Merkel cell carcinoma (MCC) mainly affects elderly patients, yet age‐stratified treatment patterns and outcomes data are scarce. Methods We analyzed 88 consecutive H&N MCC patients (2000–2022) by age (< 75 vs. ≥ 75 years). OS was estimated by Kaplan–Meier analysis and MCC‐specific death with competing‐risks methods (cause ...
Igor Vainer   +3 more
wiley   +1 more source

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