Results 61 to 70 of about 5,234,907 (203)

Merkel cell polyomavirus and associated Merkel cell carcinoma

Tumour Virus Research, 2022
Merkel cell polyomavirus (MCPyV) is a ubiquitous skin infection that can cause Merkel cell carcinoma (MCC), a highly lethal form of skin cancer with a nearly 50% mortality rate.
June F. Yang, Jianxin You
doaj   +1 more source

EHR‐Integrated Synoptic Operative Reporting for Head and Neck Oncologic Surgery

The Laryngoscope, EarlyView.
EHR‐integrated synoptic operative templates for head and neck oncologic surgery was developed and implemented at a tertiary academic cancer center. Departmental adherence rose from 49% to nearly 80% over 6 months, and 94.5% of reviewed cases met targets for complete, internally consistent documentation. The resulting structured data dictionary provides
Miriam N. Lango, Avery Sinnathamby, Marc‐Elie Nader, Paul W. Gidley, Karen Y. Choi, Mark Zafereo, Carly E. A. Barbon, Kristen B. Pytynia, Anastasios Maniakas, Amy Hessel, Ryan P. Goepfert, Faisal I. Ahmad, Jennifer L. Anderson, Sahil K. Kapur, Jolyn S. Taylor   +14 more
wiley   +1 more source

Carcinoma de células de Merkel [PDF]

, 2000
El carcinoma de células de Merkel es un tumor agresivo que debe diagnosticarse e iniciar tratamiento rápidamente.Paciente de sexo femenino, 83 años de edad, quien consultó por nódulos eritematosos en pierna izquierda de 1 año de evolución, y ...
Molina V., Verónica
core  

Artificial Intelligence for Identifying Tumor‐Reactive CD8+ T Cells: Biological Principles, Computational Advances, and Future Directions

Med Research, EarlyView.
This review details a three‐stage paradigm shift for tumor‐reactive CD8+ T‐cell identification: decoding transcriptomic states, deciphering clonal functional efficacy, and molecular‐level therapeutic TCR design. Addressing translational hurdles and generative AI “scientific blind spots”—such as missing catch bonds—we present a visionary roadmap.
Chao Yang, Yingying Sun, Yan Zhang, Yifen Shi, Zhiwen Shi   +4 more
wiley   +1 more source

Sentinel Lymph Node Biopsy in Clinically Node‐Negative Merkel Cell Carcinoma: An Update of the Westmead Hospital Experience

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Merkel cell carcinoma (MCC) is a rare, aggressive cutaneous neuroendocrine malignancy with a high risk of nodal metastasis. Sentinel lymph node biopsy (SLNB) is used to stage clinically node‐negative disease and to guide adjuvant therapy decisions.
Julie Ahn, Julie R. Howle, Michael J. Veness   +2 more
wiley   +1 more source

Combined Merkel Cell Carcinoma and Atypical Fibroxanthoma

, 2005
Background: Although there are reports of squamous cell carcinoma arising within and adjacent to Merkel cell carcinoma, and one report of an atypical fibroxanthoma-like tumor arising in an irradiated recurrent Merkel cell carcinoma, there have previously
Summer R. Youker, Elizabeth M. Billingsley   +1 more
core   +1 more source

Merkel Cell Carcinoma Display PIEZO2 Immunoreactivity [PDF]

, 2022
As an essential component of mechano-gated ion channels, critically required for mechanotransduction in mammalian cells, PIEZO2 is known to be characteristically expressed by Merkel cells in human skin.
Martín Sanz, Raquel, García-Suárez, Olivia, García Mesa, Yolanda, Cobo, Ramón, Benjamín Martín-Biedma, Vega, José Antonio, Jorge Feito, Feito Pérez, Jorge, Feito, Jorge, García-Mesa, Yolanda, Vega Álvarez, José Antonio, García Suárez, Olivia, Martín-Biedma, Benjamín, Yolanda García-Mesa, Martín Biedma, B., Martín-Sanz, Raquel, Cobo Díaz, Ramón, Jorge García-Piqueras, Saray Muñoz-Bravo, Olivia García-Suárez, Muñoz-Bravo, Saray, Raquel Martín-Sanz, García-Piqueras, Jorge, García Piqueras, Jorge, Ramón Cobo, Muñoz Bravo, Saray, José Antonio Vega   +26 more
core   +1 more source

Factors Affecting Surgical Outcomes Following Rotationplasty in Paediatric Sarcoma: A Literature Review

ANZ Journal of Surgery, EarlyView.
Rotationplasty is a durable limb‐salvage option for paediatric lower‐limb sarcoma. Across 58 studies and 1,217 patients, long‐term functional, psychosocial, and quality‐of‐life outcomes were favourable, often surpassing amputation and endoprosthetic reconstruction.
Rachel H. Ko, Stewart Morrison, Daniel J. Wilks   +2 more
wiley   +1 more source

Cardiac surveillance in immune checkpoint inhibitor therapy: Insights from the Essen Cardio‐oncology Registry

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Immune checkpoint inhibitors (ICI) have revolutionized cancer therapy, offering improvements in survival across various malignancies. However, their toxicities pose a major challenge for cardio‐oncology units. Despite their growing importance, data on effectiveness of such specialized units in mitigating ICI‐associated ...
Elias Haj‐Yehia, Lisa Zimmer, Lena Lampe, Dimitra Vlachopoulou, Matthias Totzeck, Tienush Rassaf, Raluca I. Mincu   +6 more
wiley   +1 more source

Arrhythmias associated with immune checkpoint inhibitor therapy—A clinical perspective

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy but are associated with a growing spectrum of cardiovascular immune‐related adverse events. Among these, arrhythmias represent a rare yet potentially life‐threatening complication. ICI‐induced arrhythmias encompass a wide clinical spectrum, including atrial arrhythmias, conduction ...
Dong Wang, Melanie Ricke‐Hoch, David Duncker, Johann Bauersachs, Dominik Berliner   +4 more
wiley   +1 more source