Results 71 to 80 of about 29,157 (205)

Inhibitory Immune Checkpoints beyond Programmed Cell Death Ligand 1 in Merkel Cell Carcinoma: Abundant Expression of TIGIT Independent of the Presence of Merkel Cell Polyoma Virus

open access: yesActa Dermato-Venereologica
Merkel cell carcinoma is a rare, aggressive skin cancer in which Merkel cell polyoma virus (MCPyV) is frequently pathogenically involved. After failure of anti-programmed cell death protein 1/programmed cell death ligand 1 immunotherapy, therapeutic ...
Ferdinand Toberer   +8 more
doaj   +1 more source

Merkel Cell Carcinoma: Interdisciplinary Management of a Rare Disease

open access: yesJournal of Skin Cancer, 2013
Background. The goal of this paper is to review contemporary multidisciplinary treatment with reference to Merkel cell carcinoma. Management of this rare but highly aggressive skin cancer is a complex undertaking that necessitates an understanding of its
Sven Schneider   +2 more
doaj   +1 more source

Merkel cell carcinoma with seborrheic keratosis: A unique association

open access: yesIndian Journal of Pathology and Microbiology, 2018
Merkel cell carcinoma (MCC) is a rare, clinically aggressive neuroendocrine carcinoma of the skin; MCC is 40 times less common as compared to melanoma. The most frequently reported sites have been the head and neck, extremities, and trunk.
Murthy S Anand   +3 more
doaj   +1 more source

Rare Secondary Neoplasms Arising in Epidermal Nevus: A Case Series and Literature Review

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Malignant transformation is known to occur with many nevi, such as nevus sebaceus. However, cases of secondary tumors developing in an epidermal nevus (EN) are rare, with only a few case reports documented in the literature. We present three unique cases of syringocystadenoma papilliferum (SCAP), syringofibroadenoma, trichilemmoma, and basal ...
Haya A. Homsi   +5 more
wiley   +1 more source

Merkel Cell Carcinoma

open access: yesArchives of Pathology and Laboratory Medicine, 2010
Abstract Merkel cell carcinoma is a rare, highly aggressive neuroendocrine cutaneous neoplasm with a variable clinical presentation. Histologically, it is a predominantly dermal-based lesion composed of monotonous small round cells with scanty cytoplasm, often difficult to differentiate from small round cell tumors, metastatic small ...
Hannah H, Wong, Jun, Wang
openaire   +4 more sources

Merkel cell polyomavirus and associated Merkel cell carcinoma

open access: yesTumour Virus Research, 2022
Merkel cell polyomavirus (MCPyV) is a ubiquitous skin infection that can cause Merkel cell carcinoma (MCC), a highly lethal form of skin cancer with a nearly 50% mortality rate.
June F. Yang, Jianxin You
doaj   +1 more source

A proteomic study of human Merkel Cell Carcinoma [PDF]

open access: yes, 2013
Merkel Cell Carcinoma (MCC) is an aggressive neuroendocrine cancer of the skin. The incidence has been quadrupled with a 5-year mortality rate of 46%, presently there is no cure for metastatic disease. Despite the contribution of Merkel cell polyomavirus,
Byrum, Stephanie D   +10 more
core   +3 more sources

FOXA1 is a highly sensitive diagnostic marker for prostate cancer including small cell carcinoma of the prostate

open access: yesHistopathology, EarlyView.
FOXA1 is a highly sensitive diagnostic marker for prostate cancer. Besides prostatic adenocarcinoma, it is also expressed in 57%–80% of metastatic or primary prostatic small cell carcinomas, which lose traditional prostatic markers including NKX3.1. Although it is less specific than NKX3.1, it can serve as a valuable adjunct for confirming prostatic ...
Jianping Zhao   +11 more
wiley   +1 more source

Merkel cell carcinoma of the abdominal wall

open access: yesIndian Dermatology Online Journal, 2015
Merkel cell carcinoma also known as neuroendocrine carcinoma of the skin is a very rare skin tumor. It commonly presents in the old age and the common sites are head, neck and extremities.
Vandana L Gaopande   +3 more
doaj   +1 more source

Mutational Analysis of Merkel Cell Carcinoma [PDF]

open access: yes, 2014
Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine malignancy that is associated with a poor prognosis. The pathogenesis of MCC is not well understood, and despite a recent plethora of mutational analyses, we have yet to find a set of ...
Cusack, James C., Erstad, Derek J.
core   +2 more sources

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