Results 71 to 80 of about 13,982 (210)

Rare Secondary Neoplasms Arising in Epidermal Nevus: A Case Series and Literature Review

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Malignant transformation is known to occur with many nevi, such as nevus sebaceus. However, cases of secondary tumors developing in an epidermal nevus (EN) are rare, with only a few case reports documented in the literature. We present three unique cases of syringocystadenoma papilliferum (SCAP), syringofibroadenoma, trichilemmoma, and basal ...
Haya A. Homsi, Melissa Piliang, Jennifer Lucas, Jennifer S. Ko, Steven D. Billings, Shira Ronen   +5 more
wiley   +1 more source

Merkel Cell Carcinoma, Version 1.2018

The Journal of the National Comprehensive Cancer Network, 2018
This selection from the NCCN Guidelines for Merkel Cell Carcinoma (MCC) focuses on areas impacted by recently emerging data, including sections describing MCC risk factors, diagnosis, workup, follow-up, and management of advanced disease with radiation ...
C. Bichakjian, T. Olencki, S. Aasi, Murad Alam, J. Andersen, R. Blitzblau, G. Bowen, C. Contreras, G. Daniels, R. Decker, J. Farma, Kristopher R. Fisher, B. Gastman, K. Ghosh, R. Grekin, K. Grossman, A. Ho, K. Lewis, Manisha J. Loss, D. Lydiatt, J. Messina, K. Nehal, P. Nghiem, I. Puzanov, C. Schmults, A. Shaha, V. Thomas, Yaohui Xu, J. Zic, Karin G. Hoffmann, Anita Engh   +30 more
semanticscholar   +1 more source

MCPyV Large T antigen induced atonal homolog 1 (ATOH1) is a lineage-dependency oncogene in Merkel cell carcinoma.

Journal of Investigative Dermatology, 2020
Despite the fact that the transcription factor atonal homolog 1 (ATOH1) is a master regulator of Merkel cell development, its role in Merkel cell carcinoma (MCC) carcinogenesis remains controversial.
Kaiji Fan, Jan Gravemeyer, Cathrin Ritter, Kashif Rasheed, T. Gambichler, U. Moens, M. Shuda, D. Schrama, J. Becker   +8 more
semanticscholar   +1 more source

Merkel Cell Carcinoma

Archives of Pathology and Laboratory Medicine, 2010
Abstract Merkel cell carcinoma is a rare, highly aggressive neuroendocrine cutaneous neoplasm with a variable clinical presentation. Histologically, it is a predominantly dermal-based lesion composed of monotonous small round cells with scanty cytoplasm, often difficult to differentiate from small round cell tumors, metastatic small ...
Hannah H, Wong, Jun, Wang
openaire   +4 more sources

Secondary Merkel Cell Carcinoma Manifested in the Parotid

Case Reports in Dermatological Medicine, 2013
Background. Merkel cell carcinoma of the head and neck is a rare and aggressive malignant tumour. Both the dermatological and surgical colleagues should be aware of this entity as lesions usually present on sun exposed areas of the skin such as the head ...
M. Basati, K. Kassam, A. Messiha
doaj   +1 more source

The Biology and Treatment of Merkel Cell Carcinoma: Current Understanding and Research Priorities

Nature Reviews Clinical Oncology, 2018
Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer associated with advanced age and immunosuppression. Over the past decade, an association has been discovered between MCC and either integration of the Merkel cell polyomavirus, which likely
P. Harms, K. Harms, P. Moore, J. Decaprio, P. Nghiem, M. Wong, I. Brownell   +6 more
semanticscholar   +1 more source

Merkel Cell Carcinoma With Divergent Differentiation—Or Something Else? A Triphasic Cutaneous Carcinoma With Lineage Plasticity

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Merkel cell carcinoma (MCC) is a rare, aggressive cutaneous neuroendocrine carcinoma that typically arises in sun‐exposed skin of older or immunosuppressed patients. Combined or collision tumors involving MCC and other cutaneous malignancies are uncommon, and tumors exhibiting more than two distinct malignant phenotypes are exceptionally rare.
Zeinab Khalil, Hozaifa Elameen, Ahmed K. Alomari   +2 more
wiley   +1 more source

S1 guideline sweat gland carcinoma

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary The current classification of sweat gland carcinomas is based on histomorphological characteristics and distinguishes between more than 20 entities. Most patients are older, but some subtypes also affect middle‐aged and younger patients. The majority of tumors arise de novo. Sweat gland carcinomas have nonspecific clinical features.
Mirjana Ziemer, Michael Erdmann, Abbas Agaimy, Jürgen C. Becker, Almut Böer‐Auer, Doris Helbig, Cornelia Erfurt‐Berge, Alexander Frisman, Conrad Hempel, Ulrike Leiter, Friedegund Meier, Thomas Mentzel, Lara Racz, Silke Redler, Stefan Schliep, Clemens Seidel, Alpaslan Tasdogan, Jochen Utikal, Carsten Weishaupt, Selma Ugurel   +19 more
wiley   +1 more source

Polyomavirus-driven Merkel cell carcinoma: prospects for therapeutic vaccine development

Molecular Carcinogenesis, 2020
Great strides have been made in cancer immunotherapy including the breakthrough successes of anti‐PD‐(L)1 checkpoint inhibitors. In Merkel cell carcinoma (MCC), a rare and aggressive skin cancer, PD‐(L)1 blockade is highly effective.
S. Tabachnick-Cherny, T. Pulliam, C. Church, D. Koelle, P. Nghiem   +4 more
semanticscholar   +1 more source

Merkel cell carcinoma of the abdominal wall

Indian Dermatology Online Journal, 2015
Merkel cell carcinoma also known as neuroendocrine carcinoma of the skin is a very rare skin tumor. It commonly presents in the old age and the common sites are head, neck and extremities.
Vandana L Gaopande, Avinash R Joshi, Siddhi G.S. Khandeparkar, Sanjay D Deshmukh   +3 more
doaj   +1 more source