Results 81 to 90 of about 13,982 (210)

High somatostatin receptor expression and efficacy of somatostatin analogues in patients with metastatic Merkel cell carcinoma

British Journal of Dermatology, 2020
Merkel cell carcinoma (MCC) is an aggressive, high‐grade, cutaneous neuroendocrine tumour (NET). Agents blocking programmed death 1/programmed death ligand 1 have efficacy in metastatic MCC (mMCC), but half of patients do not derive durable benefit ...
T. Akaike, J. Qazi, A. Anderson, F. Behnia, M. Shinohara, G. Akaike, D. Hippe, H. Thomas, S. Takagishi, K. Lachance, S. Y. Park, E. Tarabadkar, J. Iyer, A. Blom, U. Parvathaneni, H. Vesselle, P. Nghiem, S. Bhatia   +17 more
semanticscholar   +1 more source

Phototherapies mediated by metallic nanoparticles and near‐infrared radiation in skin cancer: A systematic review

Photochemistry and Photobiology, EarlyView.
Recent studies demonstrate that near‐infrared (NIR—750–980 nm)‐mediated photodynamic (PDT) and photothermal (PTT) therapies, combined with metallic nanoparticles (MNPs), show promising results against skin cancer, particularly melanoma, in both in vitro and in vivo models.
Tamyris Devincenzi, Alessandra Costa Lopes, Marcelo Augusto Germani Marinho, Daza de Moraes Vaz Batista Filgueira   +3 more
wiley   +1 more source

Updated efficacy of avelumab in patients with previously treated metastatic Merkel cell carcinoma after ≥1 year of follow-up: JAVELIN Merkel 200, a phase 2 clinical trial

Journal of Immunotherapy for Cancer, 2018
BackgroundMerkel cell carcinoma (MCC) is a rare, aggressive skin cancer associated with poor survival outcomes in patients with distant metastatic disease (mMCC).
H. Kaufman, J. Russell, O. Hamid, S. Bhatia, P. Terheyden, S. D’Angelo, K. Shih, C. Lebbé, M. Milella, I. Brownell, K. Lewis, J. Lorch, A. von Heydebreck, M. Hennessy, P. Nghiem   +14 more
semanticscholar   +1 more source

Merkel Cell Carcinoma: Case Report and Literature Review

Revista Iberoamericana de Cirugía de la Mano, 2020
Merkel Cell Carcinoma is a rare type of aggressive and often fatal neuroendocrine tumor of the skin. We report a clinical case of a 56-year-old female with a Merkel cell carcinoma on the left hand, without distant metastasis, treated with surgical ...
Margarida Areias Marques Miranda, Pedro Mota, Pedro Cardoso, Alexandre Pereira, Vânia Oliveira   +4 more
doaj   +1 more source

Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners

The Journal of Physiology, EarlyView.
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise, Qinglu Li, Mary G. Garry   +2 more
wiley   +1 more source

Ultrasonographic Features of Spiradenomas and Cylindromas as Diagnostic Clues in the Pre‐Therapeutic Setting

JEADV Clinical Practice, EarlyView.
Diana Crisan, Tina Weiss, Karin Scharffetter‐Kochanek, Yusef Sallum, Ioana‐Ancuta Ungureanu, Maria Crisan   +5 more
wiley   +1 more source

FOXA1 is a highly sensitive diagnostic marker for prostate cancer including small cell carcinoma of the prostate

Histopathology, Volume 89, Issue 2, Page 240-250, August 2026.
FOXA1 is a highly sensitive diagnostic marker for prostate cancer. Besides prostatic adenocarcinoma, it is also expressed in 57%–80% of metastatic or primary prostatic small cell carcinomas, which lose traditional prostatic markers including NKX3.1. Although it is less specific than NKX3.1, it can serve as a valuable adjunct for confirming prostatic ...
Jianping Zhao, Jun Yao, Hossein Hosseini, Ezra Baraban, Ruihe Lin, Charles C. Guo, Lei Huo, Wei Lu, Khaja Khan, Shufang Wang, Luisa Maren Solis Soto, Qingqing Ding   +11 more
wiley   +1 more source

Merkel cell polyomavirus infection and Merkel cell carcinoma [PDF]

Current Opinion in Virology, 2016
Merkel cell polyomavirus is the only polyomavirus discovered to date that is associated with a human cancer. MCPyV infection is highly prevalent in the general population. Nearly all healthy adults asymptomatically shed MCPyV from their skin. However, in elderly and immunosuppressed individuals, the infection can lead to a lethal form of skin cancer ...
Wei, Liu, Margo, MacDonald, Jianxin, You
openaire   +2 more sources

Clinical Relevance of Liquid Biopsy in Melanoma and Merkel Cell Carcinoma

Cancers, 2020
Melanoma and Merkel cell carcinoma are two aggressive skin malignancies with high disease-related mortality and increasing incidence rates. Currently, invasive tumor tissue biopsy is the gold standard for their diagnosis, and no reliable easily ...
M. Boyer, L. Cayrefourcq, O. Dereure, L. Meunier, O. Becquart, C. Alix‐Panabières   +5 more
semanticscholar   +1 more source

US Public Interest in Merkel Cell Carcinoma Following Jimmy Buffett’s Death and Implications for Continued Health Advocacy: Infodemiology Study of Google Trends

JMIR Dermatology
Through Jimmy Buffett’s unfortunate battle with lymphoma originating from Merkel cell carcinoma and subsequent media coverage of his death, public interest in skin cancer, Merkel cell carcinoma, and the health effects of sunlight exposure increased, as ...
Macy Haight, Hayden R Jacobs, Sarah K Boltey, Kelly A Murray, Micah Hartwell   +4 more
doaj   +1 more source