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Merkel cell carcinoma (MCC), also known as primary neuroendocrine skin carcinoma or Merkel cell tumor, is a cutaneous malignancy of neuroendocrine origin, first described by Toker in 1972. Although MCC is rare, it has been shown to have a higher mortality rate than malignant melanoma with a 5-year disease-specific survival rate of 64% [1].
Stanley J, Miller +25 more
+7 more sources
Merkel cell carcinoma is a rare cutaneous malignancy that occurs mainly in the ultraviolet-exposed areas of the head and neck region and has a mortality rate higher than that of melanoma (33%) with a tendency to recur. The clinical features, diagnosis, work up, and current recommendations for treatment of Merkel cell carcinoma are discussed.
Viola, G. +4 more
+7 more sources
Promoter activity of Merkel cell Polyomavirus variants in human dermal fibroblasts and a Merkel cell carcinoma cell line. [PDF]
Background - Merkel cell polyomavirus (MCPyV) is a human polyomavirus that establishes a life-long harmless infection in most individuals, with dermal fibroblasts believed to be the natural host cell. However, this virus is the major cause of Merkel cell
Moens, Ugo +5 more
core +1 more source
Merkel cell carcinoma is an uncommon but aggressive tumour with a high metastatic potential. A rapidly growing, non-tender cutaneous tumour on sun-exposed areas of the body in older patients should raise suspicion of the condition. It may be necessary to combine the patient history with clinical, radiological and pathological findings in order to make ...
Morten Kristoffer, Nyrud +6 more
openaire +2 more sources
CCL17/TARC and CCR4 expression in Merkel cell carcinoma [PDF]
Merkel cell carcinoma (MCC) is a rare, highly aggressive neuroendocrine skin cancer. In more than 80% of the cases, Merkel cell polyomavirus (MCPyV) is a causal factor.
Grimstad, Øystein +5 more
core +1 more source
Primary Merkel cell carcinoma of the salivary gland: a clinicopathologic study of four cases with a review of literature [PDF]
Background Primary Merkel cell carcinoma of the salivary gland is currently not listed in the World Health Organization classification. However, cases of Merkel cell type neuroendocrine carcinomas of the salivary gland with perinuclear cytokeratin 20 ...
Gyuheon Choi +6 more
doaj +1 more source
Introduction Merkel cell carcinoma is a rare malignant cutaneous neoplasm that is locally invasive and frequently metastasizes to lymph nodes, liver, lungs, bone and brain.
Söderström Kristina +2 more
doaj +1 more source
Kidney metastasis in a case of Merkel cell carcinoma
Merkel cell carcinoma is a rare neuroendocrine skin tumor with a poor prognosis. Metastasis is frequent and is seen in the first few years after diagnosis.
Abdessamade Motaouakil +5 more
doaj +1 more source
Introduction Merkel cell carcinoma and dermatofibrosarcoma protuberans are two very rare neoplasms. The simultaneous occurrence of two different tumour entities at the same anatomical site, collision tumours, is a rare phenomenon.
Tilkorn Daniel-Johannes +6 more
doaj +1 more source
Abstract Merkel cell carcinoma is a rare, highly aggressive neuroendocrine cutaneous neoplasm with a variable clinical presentation. Histologically, it is a predominantly dermal-based lesion composed of monotonous small round cells with scanty cytoplasm, often difficult to differentiate from small round cell tumors, metastatic small ...
Hannah H, Wong, Jun, Wang
openaire +4 more sources

