Results 31 to 40 of about 4,032 (162)
mBio, 2017 Merkel cell polyomavirus is the primary etiological agent of the aggressive skin cancer Merkel cell carcinoma (MCC). Recent studies have revealed that UV radiation is the primary mechanism for somatic mutagenesis in nonviral forms of MCC.
Gabriel J. Starrett +12 more
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Merkel Cell Polyomavirus in Respiratory Tract Secretions
Emerging Infectious Diseases, 2009 Merkel cell polyomavirus (MCPyV), associated with Merkel cell carcinoma, was detected in 27 of 635 nasopharyngeal aspirate samples by real-time PCR. MCPyV was more commonly found in adults than in children.
Shan Goh +3 more
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Regulation of Polyomavirus Transcription by Viral and Cellular Factors
Viruses, 2020 Polyomavirus infection is widespread in the human population. This family of viruses normally maintains latent infection within the host cell but can cause a range of human pathologies, especially in immunocompromised individuals.
June F. Yang, Jianxin You
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Infectious Entry of Merkel Cell Polyomavirus [PDF]
Journal of Virology, 2018 MCPyV is the first polyomavirus directly implicated in the development of an aggressive human cancer, Merkel cell carcinoma (MCC). Although MCPyV is constantly shed from healthy skin, the MCC incidence increases among aging and immunocompromised individuals.
Becker, Miriam +9 more
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Journal of Skin Cancer, 2012 Merkel cell carcinoma is a rare, but highly malignant tumor of the skin with high rates of metastasis and poor survival. Its incidence rate rises and is currently about 0.6/100000/year.
T. Jaeger, J. Ring, C. Andres
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Merkel Cell Polyomavirus Infection and Detection [PDF]
Journal of Visualized Experiments, 2019 Merkel cell polyomavirus (MCPyV) infection can lead to Merkel cell carcinoma (MCC), a highly aggressive form of skin cancer. Mechanistic studies to fully investigate MCPyV molecular biology and oncogenic mechanisms have been hampered by a lack of adequate cell culture models.
Wei, Liu +3 more
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Merkel Cell Polyomavirus DNA in Respiratory Specimens from Children and Adults
Emerging Infectious Diseases, 2009 Merkel cell polyomavirus (MCPyV) DNA was detected in 7 (1.3%) of 526 respiratory tract samples from patients in Australia with upper or lower respiratory tract symptoms.
Seweryn Bialasiewicz +4 more
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BMC Endocrine Disorders, 2022 Background Vulvar neuroendocrine carcinomas with small cell morphology need an appropriate differential diagnosis with respect to primary Merkel cell carcinomas, primary small cell neuroendocrine carcinomas, and secondary/metastatic carcinomas.
Tomoko Hirakawa +4 more
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Merkel cell polyomavirus is not detected in mesotheliomas [PDF]
Journal of Clinical Virology, 2010 Merkel cell polyomavirus (MCPyV) is the first polyoma virus consistently linked to the etiology of a human cancer. Serological studies indicate that the virus is commonly acquired in childhood, with seroprevalence reaching 50% or higher among young adults.
Kishor, Bhatia +2 more
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Cells, 2023 Senescent cells accumulate in the host during the aging process and are associated with age-related pathogeneses, including cancer. Although persistent senescence seems to contribute to many aspects of cellular pathways and homeostasis, the role of ...
Alexander M. Pham +3 more
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