Results 31 to 40 of about 19,515 (224)
Adverse reactions of biological therapies in patients with psoriasis [PDF]
, 2017 Psoriasis is a chronic, immune-mediated disorder characterized by well demarcated, erythematous plaques covered by thick, silvery-white scales, most often located on the knees, elbows, sacral area and scalp.
Georgescu, Simona R. +5 more
core +4 more sources
Merkel Cell Polyomavirus Infection and Detection [PDF]
Journal of Visualized Experiments, 2019 Merkel cell polyomavirus (MCPyV) infection can lead to Merkel cell carcinoma (MCC), a highly aggressive form of skin cancer. Mechanistic studies to fully investigate MCPyV molecular biology and oncogenic mechanisms have been hampered by a lack of adequate cell culture models.
Wei, Liu +3 more
openaire +2 more sources
Mining for viral fragments in methylation enriched sequencing data [PDF]
, 2015 Most next generation sequencing experiments generate more data than is required for the experimental set up. For example, methyl-CpG binding domain (MBD) affinity purification based sequencing is often used for DNA-methylation profiling, but up to 30% of
Ed eSchuuring +7 more
core +4 more sources
Polyomavirus infection in renal allograft
The Brazilian Journal of Infectious Diseases, 2013 A 32-year-old-man, an Alport Syndrome carrier X link genetic disorder,1 has developed renal insufficiency and has been on peritoneal dialysis for 10 months. In June/2011, he underwent a kidney (cadaver) transplantation with 3 panel mismatch, reactivity of lymphocytes Class I and II 0% and MIC-A negative.
Araújo, Stanley de Almeida +2 more
openaire +5 more sources
Detection and differentiation of human polyomaviruses JC and BK by LightCycler PCR [PDF]
, 2001 Human polyomaviruses JC and BK may cause several clinical manifestations in immunocompromised hosts, including progressive multifocal leukoencephalopathy and hemorrhagic cystitis.
Whiley, David M. +2 more
core +1 more source
Serological Diagnosis of Human Polyomavirus Infection [PDF]
, 2007 Measurement of antibody titres to the human polyomaviruses BK and JC has for many years had to rely on Hemagglutination inhibition. In recent years, viral serology based on virus-like particles (VLPs) in enzyme immunoassays (EIAs) has become widely used for a variety of viruses. We sought to establish a modern method for serological diagnosis of BK and
Lundstig, Annika, Dillner, Joakim
openaire +3 more sources
Seroprevalence of Trichodysplasia Spinulosa–associated Polyomavirus
Emerging Infectious Diseases, 2011 We identified a new polyomavirus in skin lesions from a patient with trichodysplasia spinulosa (TS). Apart from TS being an extremely rare disease, little is known of its epidemiology.
Els van der Meijden +6 more
doaj +1 more source
Viruses, 2020 Polyomaviruses are ubiquitous human pathogens that cause lifelong, asymptomatic infections in healthy individuals. Although these viruses are restrained by an intact immune system, immunocompromised individuals are at risk for developing severe diseases ...
Matthew D. Lauver, Aron E. Lukacher
doaj +1 more source
Prevalence of cytomegalovirus and BK polyoma virus infection in post-renal transplant patients in a tertiary care centre in South India [PDF]
Journal of Nephropathology, 2017 Background: Viral infections are a significant cause of graft loss and dysfunction in kidney transplant recipients. Cytomegalovirus and BK polyomavirus have often been explained as the most common viral etiological agents.
Kevin Manuel +4 more
doaj +1 more source
Journal for ImmunoTherapy of CancerThe cell adhesion protein CD56 has been identified as a potential therapeutic target in several solid tumors and hematological malignancies. Recently, we developed a CD56-directed antibody-drug conjugate (ADC), called Adcitmer and demonstrated its ...
David Schrama +19 more
doaj +1 more source