Results 31 to 40 of about 14,466 (180)

Seroprevalence of fourteen human polyomaviruses determined in blood donors. [PDF]

PLoS ONE, 2018
The polyomavirus family currently includes thirteen human polyomavirus (HPyV) species. In immunocompromised and elderly persons HPyVs are known to cause disease, such as progressive multifocal leukoencephalopathy (JCPyV), haemorrhagic cystitis and ...
Sergio Kamminga, Els van der Meijden, Mariet C W Feltkamp, Hans L Zaaijer   +3 more
doaj   +1 more source

Serological Diagnosis of Human Polyomavirus Infection [PDF]

, 2007
Measurement of antibody titres to the human polyomaviruses BK and JC has for many years had to rely on Hemagglutination inhibition. In recent years, viral serology based on virus-like particles (VLPs) in enzyme immunoassays (EIAs) has become widely used for a variety of viruses. We sought to establish a modern method for serological diagnosis of BK and
Lundstig, Annika, Dillner, Joakim
openaire   +3 more sources

Prevalence of IgG antibodies against Malawi polyomavirus in patients with autoimmune diseases and lymphoproliferative disorders subjected to bone marrow transplantation

Frontiers in Immunology
IntroductionHuman polyomaviruses (HPyVs) cause persistent/latent infections in a large fraction of the population. HPyV infections may cause severe diseases in immunocompromised patients.
Jérôme T. J. Nicol, Elisa Mazzoni, Maria Rosa Iaquinta, Raffaella De Pace, Pauline Gaboriaud, Natalia Maximova, Carolina Cason, Eleonora De Martino, Chiara Mazziotta, Pierre Coursaget, Antoine Touzé, Valentina Boz, Manola Comar, Manola Comar, Mauro Tognon, Fernanda Martini, Fernanda Martini   +16 more
doaj   +1 more source

WU Polyomavirus Infection in Children, Germany

Emerging Infectious Diseases, 2008
To the Editor: The human polyomaviruses JC and BK are known to cause persisting infections, which are usually asymptomatic in immunocompetent patients but may lead to severe disease in those who are immunosuppressed (1). Recently, 2 novel viruses of the family Polyomaviridae were detected in respiratory samples and named KI (2) and WU polyomavirus ...
Florian Neske, Kerstin Blessing, Franziska Ullrich, Anika Pröttel, Hans Wolfgang Kreth, Benedikt Weissbrich   +5 more
openaire   +3 more sources

Discovery of a new human polyomavirus associated with trichodysplasia spinulosa in an immunocompromized patient.

PLoS Pathogens, 2010
The Polyomaviridae constitute a family of small DNA viruses infecting a variety of hosts. In humans, polyomaviruses can cause infections of the central nervous system, urinary tract, skin, and possibly the respiratory tract.
Els van der Meijden, René W A Janssens, Chris Lauber, Jan Nico Bouwes Bavinck, Alexander E Gorbalenya, Mariet C W Feltkamp   +5 more
doaj   +1 more source

Small‐molecule inhibitors of JC polyomavirus infection [PDF]

Journal of Peptide Science, 2014
The JC polyomavirus (JCPyV) infects approximately 50% of the human population. In healthy individuals, the infection remains dormant and asymptomatic, but in immuno‐suppressed patients, it can cause progressive multifocal leukoencephalopathy (PML), a potentially fatal demyelinating disease.
Achani, Yatawara, Gabriel, Gaidos, Chamila N, Rupasinghe, Bethany A, O'Hara, Maria, Pellegrini, Walter J, Atwood, Dale F, Mierke   +6 more
openaire   +2 more sources

Merkel Cell Carcinoma With Divergent Differentiation—Or Something Else? A Triphasic Cutaneous Carcinoma With Lineage Plasticity

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Merkel cell carcinoma (MCC) is a rare, aggressive cutaneous neuroendocrine carcinoma that typically arises in sun‐exposed skin of older or immunosuppressed patients. Combined or collision tumors involving MCC and other cutaneous malignancies are uncommon, and tumors exhibiting more than two distinct malignant phenotypes are exceptionally rare.
Zeinab Khalil, Hozaifa Elameen, Ahmed K. Alomari   +2 more
wiley   +1 more source

Human polyomaviruses and cancer: an overview

Clinics, 2018
The name of the family Polyomaviridae, derives from the early observation that cells infected with murine polyomavirus induced multiple (poly) tumors (omas) in immunocompromised mice. Subsequent studies showed that many members of this family exhibit the
José Carlos Mann Prado, Telma Alves Monezi, Aline Teixeira Amorim, Vanesca Lino, Andressa Paladino, Enrique Boccardo   +5 more
doaj   +1 more source

Taking the Scenic Route: Polyomaviruses Utilize Multiple Pathways to Reach the Same Destination

Viruses, 2020
Members of the Polyomaviridae family differ in their host range, pathogenesis, and disease severity. To date, some of the most studied polyomaviruses include human JC, BK, and Merkel cell polyomavirus and non-human subspecies murine and simian virus 40 ...
Colleen L. Mayberry, Melissa S. Maginnis
doaj   +1 more source

Merkel cell carcinoma: an updated guide for pathologists

Histopathology, EarlyView.
Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine carcinoma for which the differential diagnosis can include other small cell malignancies (especially metastatic small cell carcinoma) or cutaneous carcinoma. Morphologic and immunophenotypic aberrancies in MCC can increase diagnostic challenge.
Paul W. Harms
wiley   +1 more source