Results 31 to 40 of about 15,097 (209)

The Role of Histone Post-Translational Modifications in Merkel Cell Carcinoma

Frontiers in Oncology, 2022
Merkel Cell Carcinoma (MCC) is a rare but highly aggressive form of non–melanoma skin cancer whose 5-year survival rate is 63%. Merkel cell polyomavirus (MCPyV), a small DNA tumor virus, is the etiological agent of MCC.
Chiara Mazziotta, Chiara Mazziotta, Carmen Lanzillotti, Carmen Lanzillotti, Roberta Gafà, Antoine Touzé, Marie-Alice Durand, Fernanda Martini, Fernanda Martini, Fernanda Martini, John Charles Rotondo, John Charles Rotondo   +11 more
doaj   +1 more source

In vitro and in vivo characterization of the cytomegalovirus and polyomavirus BK specific immune response [PDF]

, 2008
During my PhD thesis several aspects of the interaction of Cytomegalovirus and Polyomavirus BK with the host’s immune system were examined (see list of publications).
Egli, Adrian
core   +1 more source

BKV Agnoprotein Interacts with α-Soluble N-Ethylmaleimide-Sensitive Fusion Attachment Protein, and Negatively Influences Transport of VSVG-EGFP [PDF]

, 2011
Background: The human polyomavirus BK (BKV) infects humans worldwide and establishes a persistent infection in the kidney. The BK virus genome encodes three regulatory proteins, large and small tumor-antigen and the agnoprotein, as well as the capsid ...
Johannessen, M., Mona Johannessen, Walquist, Mari, Moens, Ugo, Walquist Mari, Spang Anne, Mari Walquist, Moens Ugo, Anne Spang, Gerits, N., Spang, Anne, Johannessen, Mona, Marte Dragset, Gerits Nancy, Johannessen Mona, Nancy Gerits, Ugo Moens, Dragset Marte, Walquist, M., Gerits, Nancy, Dragset, Marte Singsås, Dragset, M., Spang, A., Moens, U.   +23 more
core   +1 more source

Economic Evaluation of Screening for Polyomavirus Infection in Kidney Transplant Recipients: A Cost-Utility Analysis

Transplantation Direct, 2022
Background:. Screening for polyomavirus infection after kidney transplantation is recommended by clinical practice guidelines, but cost-effectiveness of this strategy is uncertain.
Germaine Wong, PhD, Thida Maung Myint, MMed, Yoon Jae Lee, MD, Jonathan C. Craig, PhD,, David Axelrod, MD, MBA, Bryce Kiberd, MD   +5 more
doaj   +1 more source

Polyomavirus nephropathy: Risk analysis in paired renal Transplant recipients

Brazilian Journal of Transplantation, 2016
Polyomavirus allograft nephropathy (PVAN) has a negative impact on allograft function and survival. Analysis of paired kidneys from same donor can help to understand the role of recipient risk factors for PVAN. This analysis can also define donor related
André Barros Albuquerque Esteves, Luiz Roberto Sousa Ulisses, Leonardo Figueiredo Camargo, Gabriel Giollo Rivelli, Marcos Vinicius de Sousa, Marilda Mazzali   +5 more
doaj   +1 more source

Merkel Cell Polyomavirus Infection and Detection [PDF]

Journal of Visualized Experiments, 2019
Merkel cell polyomavirus (MCPyV) infection can lead to Merkel cell carcinoma (MCC), a highly aggressive form of skin cancer. Mechanistic studies to fully investigate MCPyV molecular biology and oncogenic mechanisms have been hampered by a lack of adequate cell culture models.
Wei, Liu, Nathan A, Krump, Christopher B, Buck, Jianxin, You   +3 more
openaire   +2 more sources

Polyomavirus infection in renal allograft

The Brazilian Journal of Infectious Diseases, 2013
A 32-year-old-man, an Alport Syndrome carrier X link genetic disorder,1 has developed renal insufficiency and has been on peritoneal dialysis for 10 months. In June/2011, he underwent a kidney (cadaver) transplantation with 3 panel mismatch, reactivity of lymphocytes Class I and II 0% and MIC-A negative.
Araújo, Stanley de Almeida, Honorato-Sampaio, Kinulpe, Fernandes Júnior, Ladislau José   +2 more
openaire   +5 more sources

Serological Diagnosis of Human Polyomavirus Infection [PDF]

, 2007
Measurement of antibody titres to the human polyomaviruses BK and JC has for many years had to rely on Hemagglutination inhibition. In recent years, viral serology based on virus-like particles (VLPs) in enzyme immunoassays (EIAs) has become widely used for a variety of viruses. We sought to establish a modern method for serological diagnosis of BK and
Lundstig, Annika, Dillner, Joakim
openaire   +3 more sources

Mannose-binding lectin 2 polymorphisms do not influence frequency or type of infection in adults with chemotherapy induced neutropaenia. [PDF]

, 2012
BACKGROUND: Mannose-binding Lectin protein (MBL) has been suggested to be relevant in the defence against infections in immunosuppressed individuals.
Öhrmalm, Lars, Michelle Wong, Ohrmalm, L, Öhrmalm L., Lars Öhrmalm, Aust Carl, Tolfvenstam, Thomas, Tolfvenstam T., Hibberd, Martin, Wong, Michelle, Martin Hibberd, Hibberd M., Broliden K., Tolfvenstam, T,, Hibberd, M, Kristina Broliden, Thomas Tolfvenstam, Broliden, K,, Broliden, Kristina, Hibberd Martin, Broliden Kristina, Aust, C,, Wong, M, Carl Aust, Aust C., Wong M., Tolfvenstam Thomas, Öhrmalm Lars, Wong Michelle, Aust, Carl   +29 more
core   +1 more source

JCPyV VP1 Mutations in Progressive Multifocal Leukoencephalopathy: Altering Tropism or Mediating Immune Evasion?

Viruses, 2020
Polyomaviruses are ubiquitous human pathogens that cause lifelong, asymptomatic infections in healthy individuals. Although these viruses are restrained by an intact immune system, immunocompromised individuals are at risk for developing severe diseases ...
Matthew D. Lauver, Aron E. Lukacher
doaj   +1 more source