Results 11 to 20 of about 32,631 (184)
Frontiers in Microbiology, 2021 Polyomaviruses are a family of non-enveloped DNA viruses with wide host ranges. Human polyomaviruses typically cause asymptomatic infection and establish persistence but can be reactivated under certain conditions and cause severe diseases.
Wei Zou, Michael J. Imperiale
doaj +2 more sources
JC Polyomavirus Uses Extracellular Vesicles To Infect Target Cells
mBio, 2019 The endemic human JC polyomavirus (JCPyV) causes progressive multifocal leukoencephalopathy in immune-suppressed patients. The mechanisms of virus infection in vivo are not understood because the major target cells for virus in the brain do not express ...
Jenna Morris-Love +7 more
doaj +2 more sources
Regulation of Polyomavirus Transcription by Viral and Cellular Factors
Viruses, 2020 Polyomavirus infection is widespread in the human population. This family of viruses normally maintains latent infection within the host cell but can cause a range of human pathologies, especially in immunocompromised individuals.
June F. Yang, Jianxin You
doaj +2 more sources
BK polyomavirus: latency, reactivation, diseases and tumorigenesis
Frontiers in Cellular and Infection Microbiology, 2023 The identification of the first human polyomavirus BK (BKV) has been over half century, The previous epidemiological and phylogenetic studies suggest that BKV prevailed and co-evolved with humans, leading to high seroprevalence all over the world.
Xianfeng Zhou, Chunlong Zhu, Hui Li
semanticscholar +1 more source
Cancers, 2023 Simple Summary By studying the cancer-inducing ability of polyomaviruses, several milestones in cancer research crucially contributing to our current understanding of, e.g., the tumor suppressor proteins p53 and RB1 have been achieved. However, only with
R. Houben +3 more
semanticscholar +1 more source
Polyomavirus Wakes Up and Chooses Neurovirulence
Viruses, 2023 JC polyomavirus (JCPyV) is a human-specific polyomavirus that establishes a silent lifelong infection in multiple peripheral organs, predominantly those of the urinary tract, of immunocompetent individuals.
Arrienne B. Butic +3 more
semanticscholar +1 more source
The oncogenic roles of JC polyomavirus in cancer
Frontiers in Oncology, 2022 JC polyomavirus (JCPyV) belongs to the human polyomavirus family. Based on alternative splicing, the early region encodes the large and small T antigens, while the late region encodes the capsid structural proteins (VP1, VP2, and VP3) and the agnoprotein.
Hua Zheng, H. Xue, Cong-Min Zhang
semanticscholar +1 more source
BK Polyomavirus Nephropathy in Kidney Transplantation: Balancing Rejection and Infection
Viruses, 2021 BK polyomavirus nephropathy (BKVN) and allograft rejection are two closely-associated diseases on opposite ends of the immune scale in kidney transplant recipients. The principle of balancing the immune system remains the mainstay of therapeutic strategy.
Chia-Lin Shen +4 more
semanticscholar +1 more source
Merkel Cell Polyomavirus: Oncogenesis in a Stable Genome
Viruses, 2021 Merkel cell polyomavirus (MCV) is the causative agent for the majority of Merkel cell carcinoma (MCC) cases. Polyomavirus-associated MCC (MCCP) is characterized by the integration of MCV DNA into the tumor genome and a low tumor mutational burden.
Mona M Ahmed +2 more
semanticscholar +1 more source
Merkel cell polyomavirus and associated Merkel cell carcinoma
Tumour Virus Research, 2021 Merkel cell polyomavirus (MCPyV) is a ubiquitous skin infection that can cause Merkel cell carcinoma (MCC), a highly lethal form of skin cancer with a nearly 50% mortality rate.
June F. Yang, Jianxin You
semanticscholar +1 more source