Results 71 to 80 of about 9,606,964 (338)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017 BackgroundAbnormal diurnal blood pressure (BP), including nondipping patterns, assessed using ambulatory BP monitoring, have been associated with increased cardiovascular risk among white and Asian adults.
Marwah Abdalla +10 more
doaj +1 more source
Women in Ritual Slavery: Devadasi, Jogini and Mathamma in Karnataka and Andhra Pradesh, Southern India [PDF]
, 2007 This document is part of a digital collection provided by the Martin P. Catherwood Library, ILR School, Cornell University, pertaining to the effects of globalization on the workplace worldwide.
Black, Maggie
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Chakiñan, 2019 We live in a moment of hardening of nationalist discourses against immigration and racial minorities. In this conservative climate, Canada prevails as a benchmark for multicultural integration.
Fernando Pérez García
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The Second Circuit\u27s Approach to the In Connection With Requirement of Rule 10b-5 [PDF]
, 1987 This Commentary examines the evolution of the in connection with requirement within the Second Circuit, focusing on cases decided in the 1985-86 term.
Black, Barbara
core +2 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Hidden Beneath: Watermarks in the Early American Document Collection [PDF]
, 2016 This summer, as the Smith Intern at Special Collections, I was tasked with working on a hodge-podge of assembled documents, previously referred to as the “18th Century Document” collection.
Black, Tyler R.
core +1 more source
Monochrome males and colorful females:do gender and age influence the color and content of drawings? [PDF]
, 2013 Influences of educational level and gender were examined through free drawings. A total of 216 participants were recruited ranging from nursery school to university students.
Black, Fiona, Wright, Lynn
core +4 more sources