Results 41 to 50 of about 2,527,813 (283)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters +17 more
wiley +1 more source
Black-box superconducting circuit quantization
, 2012 We present a semi-classical method for determining the effective low-energy quantum Hamiltonian of weakly anharmonic superconducting circuits containing mesoscopic Josephson junctions coupled to electromagnetic environments made of an arbitrary ...
Devoret, Michel +8 more
core +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Black Box Variational Inference [PDF]
, 2013 Variational inference has become a widely used method to approximate posteriors in complex latent variables models. However, deriving a variational inference algorithm generally requires significant model-specific analysis, and these efforts can hinder ...
Blei, David M. +2 more
core +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Weizenbaum Journal of the Digital SocietyAlgorithmic transparency is high on the agenda for social media regulation. However, recent work in Science and Technology Studies questions whether this endeavor of “opening the black box” is feasible or even meaningful due to the sociotechnical ...
Paddy Leerssen
doaj +1 more source
Parameter identification of dc black-box arc model using non-linear least squares
The Journal of Engineering, 2019 The black-box arc model is known to be a useful technique to simulate dynamic arc-circuit interaction by reflecting arc characteristics. Existing researches have shown that the black-box model has been widely used to analyse the ac arc characteristics of
Kyu-Hoon Park +3 more
doaj +1 more source
Black-Box Complexity: Breaking the $O(n \log n)$ Barrier of LeadingOnes
, 2012 We show that the unrestricted black-box complexity of the $n$-dimensional XOR- and permutation-invariant LeadingOnes function class is $O(n \log (n) / \log \log n)$. This shows that the recent natural looking $O(n\log n)$ bound is not tight.
B. Doerr, S. Droste, S. Droste
core +1 more source
SSRN Electronic Journal, 2013 Abstract This chapter studies strategic behavior when agents have no information about the structure of the underlying game and they cannot observe other agents’ actions or payoffs. Even when players have no such information, there are simple payoff-based learning rules that lead to Nash equilibrium in many types of games, as shown in ...
Nax, Heinrich H +3 more
openaire +7 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source