Results 61 to 70 of about 561,399 (265)

APLIKASI BOX MODEL SEDERHANA UNTUK ESTIMASI KONSENTRASI POLUTAN BLACK CARBON DI ATMOSFER

Jurnal Presipitasi, 2018
Box Model adalah salah satu pemodelan kualitas udara yang menggunakan formulasi matematis parameter-parameter yang mempengaruhi konsentrasi polutan di udara yaitu berupa arah dan kecepatan angin, serta ketinggian.
Haryono Setiyo Huboyo, Budi Prasetyo Samadikun   +1 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

A Grey-Box Model of a DC/DC Boost Converter for PV Energy Systems

International Transactions on Electrical Energy Systems
This paper presents a grey-box model of a DC/DC boost converter for PV energy systems. The proposed model contains a white-box model part and a black-box model part together to prepare a better model for the PV boost converter.
Kerim Karabacak
doaj   +1 more source

Towards Effective Recognition of Black Box Rings

Axioms
Black box algebra is a part of computational algebra focused on probabilistic methods of solving problems in very large finite algebraic objects where deterministic approaches simply do not work.
Alexandre Borovik, Şükrü Yalçınkaya
doaj   +1 more source

Bekenstein's generalized second law of thermodynamics: The role of the hoop conjecture

Physics Letters B, 2015
Bekenstein's generalized second law (GSL) of thermodynamics asserts that the sum of black-hole entropy, SBH=Ac3/4ħG (here A is the black-hole surface area), and the ordinary entropy of matter and radiation fields in the black-hole exterior region never ...
Shahar Hod
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Performance of uncertainty-based active learning for efficient approximation of black-box functions in materials science

Scientific Reports
Obtaining a fine approximation of a black-box function is important for understanding and evaluating innovative materials. Active learning aims to improve the approximation of black-box functions with fewer training data.
Ai Koizumi, Guillaume Deffrennes, Kei Terayama, Ryo Tamura   +3 more
doaj   +1 more source