Results 41 to 50 of about 4,461,134 (292)

Black-Box Randomized Reductions in Algorithmic Mechanism Design [PDF]

SIAM Journal on Computing, 2010
We give the first black-box reduction from approximation algorithms to truthful approximation mechanisms for a non-trivial class of multi-parameter problems. Specifically, we prove that every welfare-maximization problem that admits a fully polynomial-time approximation scheme (FPTAS) and can be encoded as a packing problem also admits a truthful-in ...
Shaddin Dughmi, Tim Roughgarden
openaire   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

A comprehensive transplanting of black-box adversarial attacks from multi-class to multi-label models

Complex & Intelligent Systems
Adversarial examples generated by perturbing raw data with carefully designed, imperceptible noise have emerged as a primary security threat to artificial intelligence systems.
Zhijian Chen, Qi Zhou, Yujiang Liu, Wenjian Luo   +3 more
doaj   +1 more source

Amortized Generation of Sequential Algorithmic Recourses for Black-Box Models

Proceedings of the AAAI Conference on Artificial Intelligence, 2022
Explainable machine learning (ML) has gained traction in recent years due to the increasing adoption of ML-based systems in many sectors. Algorithmic Recourses (ARs) provide "what if" feedback of the form "if an input datapoint were x' instead of x, then an ML-based system's output would be y' instead of y." Recourses are attractive due to their ...
Sahil Verma 0003, Keegan Hines, John P. Dickerson   +2 more
openaire   +2 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Trusting AI made decisions in healthcare by making them explainable

Science Progress
Objectives In solving the trust issues surrounding machine learning algorithms whose reasoning cannot be understood, advancements can be made toward the integration of machine learning algorithms into mHealth applications.
Bojan Žlahtič, Jernej Završnik, Peter Kokol, Helena Blažun Vošner, Nina Sobotkiewicz, Barbara Antolinc Schaubach, Simona Kirbiš   +6 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

On the Relation Between Quantum Computational Speedup and Retrocausality

Quanta, 2016
We investigate the reason for the quantum speedup (quantum algorithms require fewer computation steps than their classical counterparts). We extend the representation of the quantum algorithm to the process of setting the problem, namely choosing the ...
Giuseppe Castagnoli
doaj   +1 more source

Interfacing external quantum devices to a universal quantum computer. [PDF]

PLoS ONE, 2011
We present a scheme to use external quantum devices using the universal quantum computer previously constructed. We thereby show how the universal quantum computer can utilize networked quantum information resources to carry out local computations.
Antonio A Lagana, Max A Lohe, Lorenz von Smekal   +2 more
doaj   +1 more source

What is a black box algorithm?

, 2023
Companies or institutions (Divinities) disintermediate their relations with users via decision-making algorithms (Pythias): users (mortals) are offered arbitrary decisions (oracles) during their interactions.How to apprehend these black box algorithms, from the point of view of a user or regulator?
Le Merrer, Erwan, Trédan, Gilles
openaire   +1 more source