Results 71 to 80 of about 45,642 (282)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

#TrayvonTaughtMe: Toolkit for Black and non-Black POC organizers and activists on the fifth anniversary of Trayvon's death

, 2017
The #TrayvonTaughtMe digital campaign highlights the beginnings of the Black Lives Matter movement, and how Trayvon’s extrajudicial murder and his family’s commitment to ending gun violence and strengthening communities catalyzed a generation of ...

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Tracing Emmett Till’s Legacy from Black Lives Matter back to the Civil Rights Movement

, 2020
This paper explores the legacy of the Emmett Till case as one of the core elements which binds together the Civil Rights Movement and the current Black Lives Matter in the US.
Fernández Fernández, Martín
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Recognition and Redemption: Visions of Safety and Justice in Black Lives Matter

Direito Público, 2021
In this paper, I recover and appraise the principal ways in which movements motivated by the ideal of racial justice have sought to transform how questions of police and punishment are imagined and acted upon.
Ian Loader
doaj  

Black Lives, Black Words: Transnational Solidarity and Collective Artistic Activism

Atlantis, 2020
In 2015, playwright Reginald Edmund started the Black Lives, Black Words international project in Chicago with a series of performances responding to the Black Lives Matter movement. Black Lives, Black Words aims at exploring Afrodiasporic experiences in
Paola Prieto López
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Addressing Anti-Black Racism in Higher Education: Love Letters to Blackness and Recommendations to Those Who Say They Love Us

Journal Committed to Social Change on Race and Ethnicity, 2020
We write this love letter to Black students, faculty, staff, executive leadership in higher education, and the surrounding community to center their/our Blackness. We want to acknowledge your frustration and anxiety.
Cameron C. Beatty, Tenisha Tevis, Lorraine Acker, Reginald Blockett, Eugene Parker   +4 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

“Because it’s different when you cross that border” : examining Black Canadian maleness in the era of Black Lives Matter

, 2016
The emergence of the Black Lives Matter movement has brought greater salience to the conceptualization of Black maleness and inspired a broader rethinking of Black maleness in relation to the North American society in general.
Debique, Michelle
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