Mechanistic Evaluation of Luteolin in Wound Healing of Diabetic Foot Ulcer via Nrf2 Signaling
Phytotherapy Research, EarlyView.Proposed mechanism by which Luteolin (LU) promotes diabetic foot ulcer healing. LU attenuates hyperglycemia‐induced oxidative stress and lipid peroxidation, improves endothelial cell viability, and suppresses ferroptosis through Nrf2‐dependent antioxidant signaling, thereby accelerating angiogenesis and wound repair. ABSTRACT Diabetic foot ulcers (DFUs)
Muhammed Yusuf +2 more
wiley +1 more source
A potential histoplasmosis pathogenesis mechanism mediated by a lectin of Histoplasma capsulatum with affinity to β-galactose, favoring intravascular hemagglutination. [PDF]
PLoS Negl Trop DisRamos-Martínez I +5 more
europepmc +1 more source
Farnesoid X receptor prevents hyperuricemia via activating ATP‐binding cassette subfamily G member 2
Rheumatology &Autoimmunity, EarlyView.Farnesoid X receptor (FXR) activation reduces serum uric acid levels by upregulating the intestinal urate transporter ATP‐binding cassette subfamily G member 2 (ABCG2). These findings uncover a novel metabolic pathway for urate excretion and suggest that FXR agonists (e.g., obeticholic acid), represent a promising therapeutic strategy for the treatment
Rui Li +5 more
wiley +1 more source
In Murine Disseminated Candidiasis, Serum Amyloid P Component Inhibits Inflammation and C-Reactive Protein Potentiates Inflammation. [PDF]
PathogensKlotz SA, Sobonya RE, Lipke PN.
europepmc +1 more source
Micro‐transitions and work identity: The case of academic entrepreneurs
Strategic Entrepreneurship Journal, EarlyView.Abstract Research Summary This paper examines how academic entrepreneurs—scientists who found research‐based startups while remaining in academia—construct and sustain their professional identities amid frequent transitions between academic and entrepreneurial roles.
Marouane Bousfiha, Henrik Berglund
wiley +1 more source
Convergent evolution of aerobic fermentation through divergent mechanisms acting on key shared glycolytic genes. [PDF]
EMBO JHorianopoulos LC, Rokas A, Hittinger CT.
europepmc +1 more source
Environmental Toxicology, EarlyView.ABSTRACT Despite the widespread presence of cigarette butts in the environment, the potential toxicological effects posed by microplastics (MPs) derived from them remain poorly understood. In this study, we compared the effects of MPs from conventional cigarette butts (cellulose acetate) and heated tobacco devices (cellulose acetate and polylactic acid
Andraž Dolar +9 more
wiley +1 more source
Modeling growth of <i>Lactobacillus helveticus</i> and <i>Kluyveromyces marxianus</i> isolated from fermented camel milk (shubat). [PDF]
Front MicrobiolOspanova A +7 more
europepmc +1 more source
The polysaccharide Pullulan improves the initial steps of allergen‐specific immunotherapy in dogs
Veterinary Record, EarlyView.Abstract Background Allergen‐specific immunotherapy (AIT) is the only aetiological treatment for canine atopic dermatitis (CAD). Pullulan, a polysaccharide with immunomodulatory properties, may enhance AIT outcomes when combined with allergens such as recombinant Dermatophagoides farinae 2 (Der f 2).
Franco Martini +3 more
wiley +1 more source
An Organoselenium Compound Induces Death in <i>Cryptococcus gattii</i> Yeast by Apoptosis and Necrosis and Shows Antifungal Efficacy in <i>Galleria mellonella</i>. [PDF]
ACS Omegada Costa LS +8 more
europepmc +1 more source