Results 1 to 10 of about 941,972 (192)

Combined exome and transcriptome sequencing of non-muscle-invasive bladder cancer: associations between genomic changes, expression subtypes, and clinical outcomes

open access: yesGenome Medicine, 2022
Background Three-quarters of bladder cancer patients present with early-stage disease (non-muscle-invasive bladder cancer, NMIBC, UICC TNM stages Ta, T1 and Tis); however, most next-generation sequencing studies to date have concentrated on later-stage ...
Anshita Goel   +16 more
doaj   +1 more source

Novel intravesical therapeutics in the treatment of non-muscle invasive bladder cancer: Horizon scanning

open access: yesFrontiers in Surgery, 2022
IntroductionNon-muscle-invasive bladder cancer (NMIBC) is a common and heterogeneous disease; many patients develop recurrent or progress to muscle-invasive disease.
Kelly Ward   +4 more
doaj   +1 more source

Bladder Cancer [PDF]

open access: yesJournal of the National Comprehensive Cancer Network, 2009
Bladder cancer is a heterogeneous disease, with 70% of patients presenting with superficial tumours, which tend to recur but are generally not life threatening, and 30% presenting as muscle-invasive disease associated with a high risk of death from distant metastases.
James E, Montie   +20 more
  +7 more sources

An unusual case of vaginal mass – subpubic cartilaginous cyst

open access: yesUrology Case Reports, 2021
Subpubic cartilaginous cyst is a rare form of ganglion cyst that arises on the inferior surface of the pubis symphysis. The pathophysiology is poorly understood but has been hypothesised to be secondary to mucinous degeneration of the pubic supporting ...
Elliot Anderson   +3 more
doaj   +1 more source

Bladder cancer [PDF]

open access: yesNature Reviews Disease Primers, 2017
Bladder cancer is a highly prevalent disease and is associated with substantial morbidity, mortality and cost. Environmental or occupational exposures to carcinogens, especially tobacco, are the main risk factors for bladder cancer. Most bladder cancers are diagnosed after patients present with macroscopic haematuria, and cases are confirmed after ...
Oner, Sanli   +6 more
openaire   +2 more sources

PD-L2 Is Constitutively Expressed in Normal and Malignant Urothelium

open access: yesFrontiers in Oncology, 2021
The use of immune checkpoint blockade, in particular PD-1 and PD-L1 inhibitors, is now commonplace in many clinical settings including the treatment of muscle-invasive bladder cancer (MIBC).
Alexander C. Dowell   +9 more
doaj   +1 more source

Overactive bladder [PDF]

open access: yesF1000Research, 2015
Overactive bladder syndrome is highly prevalent, and increasingly so with aging. It is characterized by the presence of urinary urgency, and can be associated with incontinence, increased voiding frequency, and nocturia. Assessment needs to exclude serious medical disorders that might present with similar symptoms, and a bladder diary is an invaluable ...
Wallace, Karen M., Drake, Marcus J.
openaire   +2 more sources

STAG2 Protein Expression in Non–muscle-invasive Bladder Cancer: Associations with Sex, Genomic and Transcriptomic Changes, and Clinical Outcomes

open access: yesEuropean Urology Open Science, 2022
Background: Mutations in STAG2 cause complete loss of STAG2 protein in approximately one-third of non–muscle-invasive bladder cancers (NMIBCs). STAG2 protein expression is easily determined via immunohistochemistry (IHC) and published data suggest that ...
Naheema S. Gordon   +9 more
doaj   +1 more source

TOpic: rare and special cases, the real "Strange cases" [PDF]

open access: yes, 2015
Introduction: The bladder hernia represents approximately 1-3% of all inguinal hernias, where patients aged more than 50 years have a higher incidence (10%).
AUTIERI, DOMENICO   +48 more
core   +1 more source

Effect of high level of bladder filling on spinal nociception and motoneuronal excitability [PDF]

open access: yes, 2015
To verify whether high level of bladder distension may counteract the inhibitory effect of descending pathways on sacral spinal cord neurons and to investigate which spinal circuitries are possibly involved in such a viscero-somatic interaction ...
Carbone, Antonio   +10 more
core   +1 more source

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