Mathematical Modeling of BCG-based Bladder Cancer Treatment Using Socio-Demographics [PDF]
Cancer is one of the most widespread diseases around the world with millions of new patients each year. Bladder cancer is one of the most prevalent types of cancer affecting all individuals alike with no obvious prototypical patient. The current standard treatment for BC follows a routine weekly Bacillus Calmette-Guerin (BCG) immunotherapy-based ...
arxiv
Evaluation of MMP‑2, MMP‑9, TIMP‑1, TIMP‑2, NGAL and MMP‑9/NGAL complex in urine and sera from patients with bladder cancer [PDF]
The identification of biomarkers in urine or serum samples from patients with bladder cancer is urgently required for the development of non-invasive methods for the diagnosis of bladder carcinoma and to facilitate follow-up surveillance, to combat the ...
Bruzzese, Dario+2 more
core +1 more source
Combined proteome and transcriptome analyses for the discovery of urinary biomarkers for urothelial carcinoma [PDF]
Background: Proteomic discovery of cancer biomarkers in body fluids is challenging because of their low abundance in a complex background. Altered gene expression in tumours may not reflect protein levels in body fluids.
A Martin+54 more
core +6 more sources
A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci. [PDF]
We conducted a multi-stage, genome-wide association study of bladder cancer with a primary scan of 591,637 SNPs in 3,532 affected individuals (cases) and 5,120 controls of European descent from five studies followed by a replication strategy, which ...
Aben, Katja K+109 more
core +2 more sources
Second primary cancer risk - the impact of applying different definitions of multiple primaries: results from a retrospective population-based cancer registry study [PDF]
Background: There is evidence that cancer survivors are at increased risk of second primary cancers. Changes in the prevalence of risk factors and diagnostic techniques may have affected more recent risks.<p></p> Methods: We examined the
A Chopra+43 more
core +3 more sources
A general two-stage progressive model of cancer natural history to project downstaging due to multi-cancer screening tests [PDF]
Multi-cancer early detection (MCED) tests offer to screen for multiple types of cancer with a single blood sample. Despite their promising diagnostic performance, evidence regarding their population benefit is not yet available. Expecting that benefit will derive from detecting cancer before it progresses to an advanced stage, we develop a general two ...
arxiv
Summary and Recommendations from the National Cancer Institute’s Clinical Trials Planning Meeting on Novel Therapeutics for Non-Muscle Invasive Bladder Cancer [PDF]
The NCI Bladder Cancer Task Force convened a Clinical Trials Planning Meeting (CTPM) Workshop focused on Novel Therapeutics for Non-Muscle Invasive Bladder Cancer (NMIBC).
Abrams+114 more
core +3 more sources
An evaluation of morphological and functional multi-parametric MRI sequences in classifying non-muscle and muscle invasive bladder cancer [PDF]
Objectives: Our goal is to determine the ability of multi-parametric magnetic resonance imaging (mpMRI) to differentiate muscle invasive bladder cancer (MIBC) from non-muscle invasive bladder cancer (NMIBC).
Barchetti, Giovanni+10 more
core +1 more source
Supported by NIH Specialized Programs of Research Excellence Grant in Genitourinary Cancer CA91846, and National Cancer Institute Grants CA16672, CA066723, and CA85078.
Anita L. Sabichi+12 more
openaire +3 more sources
Investigation Toward The Economic Feasibility of Personalized Medicine For Healthcare Service Providers: The Case of Bladder Cancer [PDF]
In today's complex healthcare landscape, the pursuit of delivering optimal patient care while navigating intricate economic dynamics poses a significant challenge for healthcare service providers (HSPs). In this already complex dynamics, the emergence of clinically promising personalized medicine based treatment aims to revolutionize medicine.
arxiv