Results 51 to 60 of about 331,825 (303)

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

Detection of genome-wide methylation changes in bladder cancer by long-read sequencing of urinary DNA

Clinical Epigenetics
Background Non-invasive urine tests for bladder cancer (BC) could reduce dependence on flexible cystoscopy for diagnosis and surveillance. Most recent developments in urine testing are based on targeted detection of genomic and/or epigenomic markers.
Anshita Goel, Benjamin J. Tura, Joanne D. Stockton, Nicholas Tovey, Luke Ames, Andrew D. Beggs, Maurice P. Zeegers, Nicholas D. James, K. K. Cheng, Richard T. Bryan, Douglas G. Ward, Roland Arnold   +11 more
doaj   +1 more source

Modulated Raman spectroscopy for enhanced identification of bladder tumor cells in urine samples [PDF]

, 2011
Standard Raman spectroscopy (SRS) is a noninvasive technique that is used in the biomedical field to discriminate between normal and cancer cells.
Herrington, C Simon, Briscoe, Tina, Andrew C. Riches, Sargeant, Harry, Canetta, Elisabetta, Riches, Andrew C., Sam Neilson, Dholakia, Kishan, Carruthers, Antonia Erika, Anna Chiara De Luca, Kishan Dholakia, Herrington, C. Simon, C. Simon Herrington, Elisabetta Canetta, Antonia E. Carruthers, De Luca, Anna Chiara, Carruthers, Antonia E., Neilson, Sam, Michael Mazilu, Harry Sargeant, Mazilu, Michael, Tina Briscoe, Riches, Andrew Clive   +22 more
core   +1 more source

Fully Wireless and Flexible Valves for Multiplexed and Prolonged Intravesical Liquid Release

Advanced Healthcare Materials, EarlyView.
A fundamental mechanism for the simultaneous control of multiple magnetic valves is reported in a miniature soft robotic patch for intravesical drug delivery, enabling fully wireless and programmable liquid release. Integrated with a bioadhesive interface and induction‐coupling‐based liquid volume sensing, the soft robotic patch is promising to enable ...
Boyang Xiao, Yi Zhu, Yusheng Wang, Janene M. Pierce, Jeffrey J. Tosoian, Xiaoguang Dong   +5 more
wiley   +1 more source

Biomarkers in bladder cancer

Histopathology, 2010
Proctor I, Stoeber K & Williams G H
(2010) Histopathology 57, 1–13
Biomarkers in bladder cancerCancer biomarkers provide an opportunity to diagnose tumours earlier and with greater accuracy. They can also identify those patients most at risk of disease recurrence and predict which tumours will respond to different therapeutic approaches.
Proctor, Ian, Stoeber, Kai, Williams, Gareth   +2 more
openaire   +5 more sources

Unlocking the Potential of MXene‐Based Electrochemical Biosensors: A Review of Biofunctionalization Strategies and Biosensing Principles

Advanced Materials Technologies, EarlyView.
ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali, Sharat Chandra Barman, Isobel Steer, Aya H. Alshareef, Dana Alsulaiman   +4 more
wiley   +1 more source

Enfortumab vedotin–related cutaneous toxicity correlates with overall survival in patients with urothelial cancer: a retrospective experience

Frontiers in Oncology
IntroductionEnfortumab vedotin (EV) is an antibody drug conjugate approved for advanced urothelial cancer, consisting of a monomethyl auristatin E payload linked to a human monoclonal antibody targeting nectin-4.
Evangelia Vlachou, Evangelia Vlachou, Burles Avner Johnson, Burles Avner Johnson, David McConkey, David McConkey, Yuezhou Jing, Andres Matoso, Andres Matoso, Andres Matoso, Andres Matoso, Noah M. Hahn, Noah M. Hahn, Noah M. Hahn, Jean Hoffman-Censits, Jean Hoffman-Censits, Jean Hoffman-Censits   +16 more
doaj   +1 more source

Single Arm Phase I/II Study of Everolimus and Intravesical Gemcitabine in Patients with Primary or Secondary Carcinoma of the Bladder who failed Bacillus Calmette Guerin (NCT01259063)

Bladder Cancer, 2017
Background: Standard treatment for BCG-refractory urothelial cancer is radical cystectomy. Identification of active agents is clearly warranted. Objective: To determine a safe dose of oral everolimus in combination with standard intravesical gemcitabine ...
Guido Dalbagni, Nicole Benfante, Daniel D. Sjoberg, Bernard H. Bochner, S. Machele Donat, Harry W. Herr, Asia S. Mc Coy, Alicia J. Fahrner, Caitlyn Retinger, Jonathan E. Rosenberg, Dean F. Bajorin   +10 more
doaj   +1 more source

A cell line derived from BBN (N-butyl-N-[4-hydroxybutyl]-nitrosamine)-induced rat bladder cancer: establishment and scanning electron microscopic cell surface characteristics

, 1978
This research was performed to establish a cell line from experimental bladder tumor and to discuss the biological characteristics of the cell line so established. Tissue cultures of epithelial cells were derived from a rat bladder cancer induced by BBN.
Nishi, Mitsuo
core   +1 more source

Toward Wireless Implantable Robotic Systems Driven by Magnetic Field for Personalized Therapy

Advanced Robotics Research, EarlyView.
Robotic materials are playing an increasingly vital role in enabling sensing and actuation at small scales. This perspective highlights recent advances in magnetic materials and magnetically actuated devices for wireless sensing, actuation, and energy harvesting toward implantable robotic systems for closed‐loop therapy.
Yusheng Wang, Ruijian Ge, Xiaoguang Dong
wiley   +1 more source